A5102738074- Microfluidic and Bio-sensing Technologies
- Neuroscience and Neural Engineering
- 3D Printing in Biomedical Research
- GaN-based semiconductor devices and materials
- Microfluidic and Capillary Electrophoresis Applications
- Photonic and Optical Devices
- Lymphoma Diagnosis and Treatment
- Ga2O3 and related materials
- Advanced Fiber Optic Sensors
- Semiconductor Quantum Structures and Devices
- Plasmonic and Surface Plasmon Research
- Chronic Lymphocytic Leukemia Research
- Nanowire Synthesis and Applications
- Advanced Photocatalysis Techniques
- Viral Infections and Immunology Research
- T-cell and Retrovirus Studies
- Biosensors and Analytical Detection
- Semiconductor Lasers and Optical Devices
- Gold and Silver Nanoparticles Synthesis and Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Animal Virus Infections Studies
- Metal and Thin Film Mechanics
- Analytical Chemistry and Sensors
- ZnO doping and properties
- Solid State Laser Technologies
Chinese Academy of Sciences
2016-2025
Institute of Microelectronics
2011-2025
Chongqing Cancer Hospital
2022-2024
Chongqing University
2022-2024
Tianjin University of Commerce
2024
Fuzhou University
2021-2024
Guangzhou College of Commerce
2023
Yichun University
2019-2021
Institute of Modern Physics
2018-2019
University of Chinese Academy of Sciences
2019
A microsphere mediated exosome isolation and ultra-sensitive detection ExoDEP-chip was developed. limit of 193 exosomes per mL obtained by dispersing PS microspheres into microwells to reduce the fluorescence interference.
We designed a 3D cell impedance sensor for nanotoxicology: it integrates PVEA chip with multi-channel system dynamic monitoring of metal nanoparticle toxicity, enhancing accuracy in toxicity detection.
Wide-field inspection, nano detection, and real-time observation are essential for investigating biomolecular interaction processes. Surface plasmon resonance microscopy (SPRM) is a label-free, real-time, nano-imaging method that widely employed the dynamic detection of nanoscale biomolecules. The field view (FOV) SPRM limited by usage high NA objectives, scanning required to obtain large FOV. However, during scanning, focus drift introduced mechanical vibrations blurs imaging quality SPRM,...
In the recent wake of Sustainable Development Goals introduced by United Nations, topic green innovation has achieved much attention. This study aims to explore impact on trade credit activities. The empirical analysis was conducted sampling ten years financial data (2010–2019) publicly listed enterprises in Brazil, Russia, India, China, and South Africa. To overcome endogeneity, we utilize system generalized method moments technique for regression analysis. reveals that a positive...
Abstract Simultaneously achieving high sensitivity and detection speed with traditional solid-state biosensors is usually limited since the target molecules must passively diffuse to sensor surface before they can be detected. Microfluidic techniques have been applied shorten diffusion time by continuously moving through biosensing regions. However, binding efficiencies of biomolecules are still inherent laminar flow inside microscale channels. In this study, focused traveling acoustic waves...
Self-assembly at the air/water interface (AWI) has proven to be an efficient strategy for fabricating two-dimensional (2D) colloidal monolayers, which was widely used as template nanosphere lithography in nanophononics, optofluidics, and solar cell studies. However, monolayers fabricated AWI usually suffer from a small domain area quasi-double layer structure caused by submerged particles. To overcome this, we proposed improved protocol prepare 2D free of overlapping nanospheres AWI....
A series of samples with varying growth pressure are grown and their optical structural properties investigated. It is found that the residual carbon concentration decreases when reactor increases from 80 to 450 Torr during InGaN/GaN multiple quantum well growth. results in an enhanced peak intensity electroluminescence because impurities can induce deep energy levels act as non-radiative recombination centers InGaN layers.
Non-specific adsorption (NSA) of proteins on surface is a critical issue in polydimethylsiloxane (PDMS)-based microfluidics, which may either considerably decrease the efficiency continuous flow reaction or cause large background noise heterogeneous sensing. This work introduced new method to restrain NSA protein by caulking PDMS with Parylene C, i.e., forming C-caulked (pcPDMS) surface. The depth C inside matrix was characterized laser scanning confocal microscopy based detectable...
Parylene C is a widely used polymer material in microfabrication because of its excellent properties such as chemical inertness, biocompatibility and flexibility. It has been commonly adopted structural for variety microfluidics bio-MEMS (micro-electro-mechanical system) applications. However, it still difficult to achieve controllable pattern, especially on film thicker than couple micrometers. Here, we proposed an SF₆ optimized O₂ plasma etching (SOOE) C, with titanium the mask. Without...
The electroporation system can serve as a tool for the intracellular delivery of foreign cargos. However, this technique is presently limited by inaccurate electric field applied to single cells and lack real-time metrics subsystem. Here, we reported microfluidic precise rapid single-cell simultaneous impedance monitoring in constriction microchannel. When (A549) were continuously passing through microchannel, localized high was on cell membrane, which resulted highly efficient (up 96.6%)...
Abstract Real-time transformation was important for the practical implementation of impedance flow cytometry. The major obstacle time-consuming step translating raw data to cellular intrinsic electrical properties (e.g., specific membrane capacitance C sm and cytoplasm conductivity σ cyto ). Although optimization strategies such as neural network-aided were recently reported provide an impressive boost translation process, simultaneously achieving high speed, accuracy, generalization...
The photocatalytic conversion of CO2 into hydrocarbon fuel holds immense potential for achieving a carbon closed loop and neutrality. Developing efficient photocatalysts plays pivotal role in enabling the widespread application reduction on large scale. Herein, novel S-scheme MnWO4/LaTiO2N heterojunction composite is successfully synthesized by hydrothermal method. This catalyst demonstrates excellent activity to CO CH4 using water molecules as electron donors under visible light...
A t-CVD Parylene technique was advanced to caulk the molecular network of PDMS while retaining its original surface properties.
Abstract Three series of samples with different NH 3 flow rate are grown and the optical structural properties investigated. It is found that apart from a positive effect on keeping high partial pressure nitrogen to enhance indium incorporation, may also play negative incorporation during InGaN growth. Especially, when temperature relatively high, hydrogen generated dissociation suppress chemical reaction which produces InN, leading reduced efficiency layer
The trans-epithelial electrical resistance (TEER) is widely used to quantitatively evaluate cellular barrier function at the organ level in vitro. measurement of TEER organ-on-chips (organ chips) plays a significant role medical and pharmacological research. However, due limitation equivalent model for chips, existing measurements usually neglect changes during cell proliferation, resulting low accuracy measurements. Here, we proposed new whole-region developed real-time system that contains...
Micro-structural characteristics and electrical properties of an n-type GaN epilayer on Al2O3 irradiated by 290-MeV 238U32+ ions to various fluences were investigated using atomic force microscopy (AFM), scanning electron (SEM), high-resolution X-ray diffraction (HRXRD), Raman scattering spectroscopy. AFM images show that the nano-hillocks generated, diameter density nano-hillocks, increase obviously with increasing ion fluence, accompanied in surface roughness. SEM display Al, O, C elements...
Conventionally, Porcine teschovirus (PTV) consists of 13 genotypes (PTV 1-13, which belong to Teschovirus A); however, several novel members including PTV 14-22 have been discovered recently. 21 was identified as a species named B. In this study, almost all 22 reported except 6, 7, 12 and 20 were in the pig populations western Jiangxi, China, reflects high genotype diversity. Moreover, best our knowledge, nearly complete genome 22-JiangX1 first sequenced present study. The homology...
With the development of advanced nanofabrication techniques over past decades, different nanostructure-based plasmonic fiber-optic sensors have been developed and presented a low limit detection for various biomolecules. However, owing to both dependence on complex equipment trade-off between fabrication cost sensing performance, nanostructured are rarely used outside laboratories. To facilitate wider application sensors, parylene-mediated hybrid plasmonic-photonic cavity-based sensor was...