A5006907582- Orbital Angular Momentum in Optics
- Microfluidic and Bio-sensing Technologies
- Diffusion and Search Dynamics
- Digital Holography and Microscopy
- Advanced Thermodynamics and Statistical Mechanics
- Cellular Mechanics and Interactions
- Advanced Fluorescence Microscopy Techniques
- stochastic dynamics and bifurcation
- Micro and Nano Robotics
- Near-Field Optical Microscopy
- Material Dynamics and Properties
- Photonic Crystals and Applications
- Force Microscopy Techniques and Applications
- Photonic and Optical Devices
- Neural dynamics and brain function
- Cold Atom Physics and Bose-Einstein Condensates
- Lipid Membrane Structure and Behavior
- Blood properties and coagulation
- Rheology and Fluid Dynamics Studies
- Plasmonic and Surface Plasmon Research
- Advanced Electron Microscopy Techniques and Applications
- Cardiomyopathy and Myosin Studies
- Supramolecular Self-Assembly in Materials
- Pickering emulsions and particle stabilization
- Ecosystem dynamics and resilience
Tel Aviv University
2016-2025
Arthur M. Sackler Gallery
2019-2020
New York Proton Center
2011
New York University
2005-2009
Technion – Israel Institute of Technology
1999-2004
Stochastic resetting is prevalent in natural and man-made systems, giving rise to a long series of nonequilibrium phenomena. Diffusion with stochastic serves as paradigmatic model study these phenomena, but the lack well-controlled platform by which this process can be studied experimentally has been major impediment research field. Here, we report experimental realization colloidal particle diffusion via holographic optical tweezers. We provide first corroboration central theoretical...
We present a new tomographic phase microscopy (TPM) approach that allows capturing the three-dimensional refractive index structure of single cells in suspension without labeling, using 180° rotation cells. This is obtained by integrating an external off-axis interferometer for wide-field wave front acquisition with holographic optical tweezers (HOTs) trapping and micro-rotation suspended In contrast to existing TPM approaches cell imaging, our does not require anchoring sample rotating...
Abstract Optical tweezers are tools made of light that enable contactless pushing, trapping, and manipulation objects, ranging from atoms to space sails. Since the pioneering work by Arthur Ashkin in 1970s, optical have evolved into sophisticated instruments been employed a broad range applications life sciences, physics, engineering. These include accurate force torque measurement at femtonewton level, microrheology complex fluids, single micro- nano-particle spectroscopy, single-cell...
Stochastic resetting, a method for accelerating target search in random processes, often incurs temporal and energetic costs. For diffusing particle, lower bound exists the cost of reaching target, which is attained at low resetting rates equals direct linear transportation against fluid drag. Here, we study smart strategy that aims to beat this bound. By strategically particle only when benefits its progress toward leverages information minimize energy consumption. We analytically calculate...
We demonstrate that semiconductor nanowires can be translated, rotated, cut, fused and organized into nontrivial structures using holographic optical traps. The approach to nano-assembly allows for simultaneous independent manipulation of multiple nanowires, including relative translation rotation.
We demonstrate both theoretically and experimentally that phase gradients in a light field can be used to create new category of optical traps complementary the more familiar intensity-gradient known as tweezers. further show work done by phase-gradient forces is path dependent briefly discuss some ramifications this nonconservativity.
Holographic optical tweezers use computer-generated holograms to create arbitrary three-dimensional configurations of single-beam traps that are useful for capturing, moving, and transforming mesoscopic objects. Through a combination beam-splitting, mode-forming, adaptive wavefront correction, holographic can exert precisely specified characterized forces torques on objects ranging in size from few nanometers hundreds micrometers. Offering nanometer-scale spatial resolution real-time...
Holographic optical traps use the forces exerted by computer-generated holograms to trap, move and otherwise transform mesoscopically textured materials. This article introduces methods for optimizing holographic traps' efficiency accuracy, an optimal statistical approach characterizing their performance. combination makes possible real-time adaptive optimization.
The diffraction limited resolution of light focused by a lens was derived in 1873 Ernst Abbe. Later 1952, method to reach sub-diffraction spots proposed modulating the wavefront beam. In related development, super-oscillating functions, i.e. band functions that locally oscillate faster than their highest Fourier component, were introduced and experimentally applied for super-resolution microscopy. Up till now, only simple Gaussian-like used. Here we show amplitude phase profile these can be...
Search processes in the natural world are often punctuated by home returns that reset position of foraging animals, birds, and insects. Many theoretical, numerical, experimental studies have now demonstrated this strategy can drastically facilitate search, which could explain its prevalence. To further foragers also work as a group: modifying their surroundings highly sophisticated ways, e.g., leaving chemical scent trails imprint memory previous excursions. Here, we design controlled...
We present and characterize a method to accelerate the relaxation of Brownian object between two distinct equilibrium states. Instead relying on deterministic time-dependent control parameter, we use stochastic resetting guide transient evolution. The protocol is investigated theoretically, its thermodynamic cost evaluated with tools thermodynamics. Remarkably, show that significantly accelerates final state. This exhibits energetic temporal characteristics align scales observed in...
Azoles are the most commonly used class of antifungal drugs, yet where they localize within fungal cells and how imported remain poorly understood. Azole antifungals target lanosterol 14α-demethylase, a cytochrome P450, encoded by ERG11 in Candida albicans, prevalent pathogen. We report synthesis fluorescent probes that permit visualization azoles live cells. Probe 1 is dansyl dye-conjugated azole, probe 2 Cy5-conjugated azole. Docking computations indicated each can occupy active site P450....
This paper shows how disorder in the arrangement of obstacles induces Fickian yet non-Gaussian diffusion tracer particles. The authors show that superstatistical behavior, arising from spatial heterogeneity, leads to non-Gaussianity via two coupled physical mechanisms.
Quasicrystals have a higher degree of rotational and point-reflection symmetry than conventional crystals. As result, quasicrystalline heterostructures fabricated from dielectric materials with micrometer-scale features exhibit interesting useful optical properties including large photonic bandgaps in two-dimensional systems. We demonstrate the holographic assembly three-dimensional heterostructures, structures specifically engineered defects. The highly uniform quasiperiodic arrays traps...
We assess the influence of geometric aberrations on in-plane performance optical traps by studying dynamics trapped colloidal spheres in deliberately distorted holographic tweezers. The lateral stiffness turns out to be insensitive moderate amounts coma, astigmatism, and spherical aberration. Moreover aberration correction enables us compensate inherent shortcomings train, thereby adaptively improving its performance. also demonstrate effects intensity profiles vortices, whose readily...
Inspired by many examples in nature, stochastic resetting of random processes has been studied extensively the past decade. In particular, various models particle motion were considered where, upon resetting, is returned to its initial position. Here we generalize model diffusion with account for situations where a only fraction distance origin, e.g., half way. We show that this always attains steady-state distribution which can be written as an infinite sum independent, but not identical,...
Viscously damped particles driven past an evenly spaced array of potential energy wells or barriers may become kinetically locked in to the array, else escape from array. The transition between locked-in and free-running states has been predicted depend sensitively on ratio particles' size separation wells. This prediction is confirmed by measurements monodisperse colloidal spheres through arrays holographic optical traps.
Colloidal spheres driven through water along a circular path by an optical ring trap display unexpected dynamical correlations. We use Stokesian dynamics simulations and simple analytical model to demonstrate that the path's curvature breaks symmetry of two-body hydrodynamic interaction, resulting in particle pairing. The influence this effective nonequilibrium attraction diminishes as either temperature or stiffness radial confinement increases. find well-defined set dynamically paired...
Eukaryotic cells rely on their cytoskeleton to carry out coordinated motion, transport materials within them, and interact mechanically with environment. To adapt the changing requirements, cell's constantly remodels through action of myosin II motor clusters that numerous actin filaments simultaneously. Here we study various roles in formation evolution vitro actomyosin networks as a model system for cytoskeleton. In our experiments can vary size between 14 144 molecules apply forces...
We experimentally realize a Maxwell's demon that converts information gained by measurements to work. Our setup is composed of colloidal particle in channel filled with flowing fluid. A barrier made light prevents the from being carried away flow. The then performs biased Brownian motion vicinity barrier. particle's position measured periodically. When found be far enough barrier, feedback applied moving upstream while maintaining given minimal distance particle. At steady state, net effect...
Trapping and manipulation of particles using laser beams has become an important tool in diverse fields research. In recent years, particular interest been devoted to the problem conveying optically trapped over extended distances either downstream or upstream direction photon momentum flow. Here, we propose experimentally demonstrate optical analog famous Archimedes’ screw where rotation a helical-intensity beam is transferred axial motion micrometer-scale, airborne, carbon-based particles....
We experimentally determine the conditions under which a fluctuation-dissipation relation holds for tracer particle in an active bath of self-propelled walkers, yielding effective temperature that coincides with particle’s potential energy.
Particle-tracking microrheology probes the rheology of soft materials by accurately tracking an ensemble embedded colloidal tracer particles. One-particle analysis, which focuses on trajectory individual tracers is ideal for homogeneous that do not interact with By contrast, characterization heterogeneous, micro-structured or those where particles directly medium requires a two-particle analysis characterizes correlations between trajectories distinct particle pairs. Here, we propose...