A5055654523- Clinical Nutrition and Gastroenterology
- Childhood Cancer Survivors' Quality of Life
- Musculoskeletal pain and rehabilitation
- Suicide and Self-Harm Studies
- Banking stability, regulation, efficiency
- Nutrition and Health in Aging
- Child and Adolescent Psychosocial and Emotional Development
- Osteoarthritis Treatment and Mechanisms
- Health Systems, Economic Evaluations, Quality of Life
- Knee injuries and reconstruction techniques
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Financial Literacy, Pension, Retirement Analysis
- Housing, Finance, and Neoliberalism
- Fiscal Policy and Economic Growth
- Bone fractures and treatments
- Plant Diversity and Evolution
- Food Security and Health in Diverse Populations
- Advanced MRI Techniques and Applications
- Botany, Ecology, and Taxonomy Studies
- Substance Abuse Treatment and Outcomes
- Global Maternal and Child Health
- Pain Management and Opioid Use
- Shoulder Injury and Treatment
- Islamic Finance and Banking Studies
- Local Government Finance and Decentralization
Hospital for Special Surgery
2021-2024
Boston Children's Hospital
2024
Great Ormond Street Hospital
2020-2024
University College London
2006-2024
Aston University
2022-2024
New Mexico Department of Health
2010-2024
NIHR Great Ormond Street Hospital Biomedical Research Centre
2024
University of Sheffield
2020-2023
Community Link
2023
Sheffield Hallam University
2023
ABSTRACT Portfolio allocation decisions increasingly incorporate social values. We develop a tractable framework to study how competition between investors own socially valuable assets affects welfare. Relative the most common social‐investing strategies, we identify alternative strategies that result in higher impact and financial returns. for have when is difficult measure. From firm's perspective, increasing profitability can greater than directly value. present new empirical evidence on...
Cancer patients receiving chemotherapy have a high risk of malnutrition secondary to the disease and treatment, 40–80 % cancer suffer from different degrees malnutrition, depending on tumour subtype, location, staging treatment strategy. Malnutrition in affects patient's overall condition, it increases number complications, adverse effects reduces quality life. The aim present study was evaluate weight-loss prevalence site gastrointestinal (GI) symptoms oncology chemotherapy. We included 191...
Opioid prescription at baseline was significantly associated with greater self-reported disability in back pain patients 6 months after adjusting for confounders. prescribing chronic noncancer is increasing, but there limited knowledge about longer-term outcomes of people receiving opioids conditions such as pain. This study aimed to explore the relationship between prescribed and among consulting primary care A total 715 participants from a prospective cohort study, who gave consent review...
Portfolio allocation decisions increasingly incorporate social values. The most common of these strategies are misguided. We develop a tractable framework in which commercial and investors compete, identify alternative for that result higher welfare financial returns. From the enterprise perspective, increasing profitability can have greater impact than directly value creation. Whether firms exhibit positive or negative assortative matching depends on nature preferences. present empirical...
To prospectively study the value of adjuvant chemotherapy in pediatric patients with surgically resected nonrhabdomyosarcomatous soft tissue sarcomas (NRSTS).From June 1986 to May 1992, after complete surgical resection (+/-radiotherapy) their NRSTS, 81 eligible either received comprising vincristine, dactinomycin, cyclophosphamide, and doxorubicin or were observed. Only 30 accepted randomization, 15 assigned each regimen. Of remaining 51 patients, 19 elected 32 observation.Patients...
Abstract Background Previous research has identified similar prognostic factors in patients with musculoskeletal ( MSK ) conditions regardless of pain presentation, generating opportunities for management based on prognosis rather than specific presentation. Methods Data from seven RCT s (2483 participants) evaluating a range primary care interventions different were used to investigate the course symptoms and explore similarities differences predictors outcome. The value site predicting...
The incidence of meniscus tears and ACL in pediatric patients continues to rise, bringing question the risk factors associated with these injuries. As are commonly repaired populations, epidemiology repairable is an important for consideration surgeons evaluating treatment options.To describe meniscal tear patterns adolescent who underwent repair across multiple institutions surgeons, as well evaluate relationship between age, sex, body mass index (BMI) their effect on prevalence, type,...
Gastric cancer is the most frequent tumor of digestive tract in Mexico. Most patients are diagnosed at advanced stages, and fatal outcome expected. One hundred fifty patient charts were retrospectively reviewed. Univariate multivariate analyses performed to evaluate impact clinicopathologic treatment variables on survival. (75%) harboring poorly differentiated tumors. Surgery, mostly palliative, was 114 patients. Chemotherapy administered 47 On univariate analysis, significant prognostic...
The purpose of this study was to evaluate the role ethanol in deaths due heroin intoxication. Over a 12 month period, all cases investigated by Office Chief Medical Examiner, State Maryland where blood screen Roche Abuscreen radioimmunoassay (RIA) positive at cutoff 100 ng/mL were included study. Free morphine quantitated using Coat-A-Count RIA and head space gas chromatography. All presumptive confirmed chromatography/mass spectrometry. Seventy 119 death attributed narcotic or alcohol...
The in vivo rat model is a workhorse neuroscience research, preclinical studies and drug development. A repertoire of MR tools has been developed for its investigation; however, high levels B 0 magnetic field homogeneity are required meaningful results. homogenization fields the brain, i.e. shimming, difficult task because multitude complex, susceptibility‐induced distortions. Conventional shimming with spherical harmonic (SH) functions capable compensating shallow distortions limited areas,...
How valuable are restrictive debt covenants in reducing the agency costs of debt? I exploit revealed preference decision to refinance fixed-coupon bonds, which weighs observable interest rate savings against unobservable a change covenants. Variation this trade-off reveals that firms require higher when it would add structurally estimate model refinancing and find high-yield bond's covenant package increases value speculative-grade by 2.4 percent. This suggests essential for allowing tax...
Background This study aimed to evaluate whether prompting general practitioners (GPs) routinely assess and manage anxiety depression in patients consulting with osteoarthritis (OA) improves pain outcomes. Methods findings We conducted a cluster randomised controlled trial involving 45 English practices. In intervention practices, aged ≥45 y OA received point-of-care screening by the GP, prompted an automated electronic template comprising five questions (a two-item Patient Health...
We study whether exit policies by financial institutions are an effective tool to address climate change, using bank targeting the coal industry around world as a laboratory. In contrast theories predicting divestment be ineffective because capital is highly substitutable, we find large effects of these policies. first develop comprehensive set measures policy strength, and document heterogeneity along this dimension. Using shift-share instrument combining bank-level strength timing with...
ABSTRACT BACKGROUND Youth suicide is a serious public health problem in the United States. School environments, and attention of school adults, are promising but minimally studied avenues for promoting mental among students. METHODS The 2013 New Mexico Risk Resiliency Survey data were analyzed to identify ways which environment influences attempts sample Hispanic Factors examined were: relationships with speaking language other than English at home, being born outside States not having...
Abstract Purpose: Pathologic angiogenesis has been correlated with tumor growth, dissemination, metastasis, and prognosis in solid tumors including breast cancer. Angiogenesis also implicated the pathophysiology of, shown to be a therapeutic target arising bone marrow. The status of marrow cancer patients is unknown. aim this study was estimate extent subset patients. Experimental Design: We studied 42 women whom biopsy done. Bone samples were sorted according their infiltration by cells. In...
Objectives The study investigated (1) the association between comorbidity and multidrug prescribing compared with index condition, (2) vascular non-vascular condition key drug prescribing. Design Cross-sectional linking anonymised computer consultations prescription records for a 2-year time period. Setting 11 general practices in North Staffordshire, England. Participants Study groups aged 40 years over (N=12 875). Within six conditions, comorbid group other five conditions was an ‘alone’...