A5021288610- Reproductive Biology and Fertility
- Animal Genetics and Reproduction
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Spectroscopy and Quantum Chemical Studies
- Conducting polymers and applications
- Molecular Junctions and Nanostructures
- Tissue Engineering and Regenerative Medicine
- Porphyrin and Phthalocyanine Chemistry
- dental development and anomalies
- Advanced Chemical Physics Studies
- Lipid Membrane Structure and Behavior
- Pluripotent Stem Cells Research
- Organic and Molecular Conductors Research
- Electron and X-Ray Spectroscopy Techniques
- Organic Electronics and Photovoltaics
- Dental materials and restorations
- Polydiacetylene-based materials and applications
- Laser Applications in Dentistry and Medicine
- Polymer composites and self-healing
- Sexual Differentiation and Disorders
- Hypothalamic control of reproductive hormones
- Advancements in Photolithography Techniques
- Supramolecular Self-Assembly in Materials
- Dental Radiography and Imaging
- Phosphorus and nutrient management
National Institute of Genetics
2015-2021
The Graduate University for Advanced Studies, SOKENDAI
2015-2021
Saitama University
1983-2001
Urawa University
1983-1999
Fukuda Denshi (Japan)
1996-1997
Hammersmith Hospital
1997
Ladies College
1996
Tokyo Metropolitan University
1996
Okazaki National Research Institutes
1990
We investigated a possible relationship between the Kobe earthquake (January 17, 1995) and quality of semen. assessed sperm concentration motility 27 male patients who had more than 30 million/ ml >40% within 5 months before earthquake. Twelve from districts with magnitude <4 on Richter scale showed no difference in after Of 15 >6, five whose houses received damage distinct changes motility. In contrast, 10 were partially or completely destroyed significantly (P < 0.001) lower before,...
Ultraviolet photoelectron spectroscopy (UPS) has been applied to the investigation of electronic structure oligothiophenes with 4–8 thiophene rings. In a series α-linked oligomers (αn n being number rings), systematic evolution π band is observed. Several peaks which correspond are observed in region 0.7–3 eV below Fermi level (EF), and bandwidth becomes broader increasing n. The nonbonding at 3.5 EF its energy almost independent units. UPS spectra α7 α8 fairly similar polythiophene, showing...
The sex of primordial germ cells (PGCs) is determined in developing gonads on the basis cues from somatic cells. In XY gonads, sex-determining region Y (SRY) triggers fibroblast growth factor 9 (FGF9) expression FGF signaling, together with downstream nodal/activin promotes male differentiation by suppressing retinoic acid (RA)-dependent meiotic entry and inducing male-specific genes. However, mechanism which signaling regulates PGC fate unknown. We uncovered roles SMAD2/3 p38 MAPK, putative...
The differential programming of sperm and eggs in gonads is a fundamental topic reproductive biology. Although the sexual fate germ cells believed to be determined by signaling factors from sexually differentiated somatic fetal gonads, molecular mechanism that determines cell poorly understood. Herein, we show mothers against decapentaplegic homolog 4 (SMAD4) required for female-type differentiation. Germ Smad4-deficient ovaries respond retinoic acid but fail undergo meiotic prophase I,...
Functional oocytes are produced through complex molecular and cellular processes. In particular, the contribution of post-transcriptional gene regulation mediated by RNA-binding proteins (RBPs) is crucial for controlling proper expression during this process. DAZL (deleted in azoospermia-like) one RBPs required sexual differentiation primordial germ cells progression meiosis ovulated oocytes. However, involvement development follicular still unknown. Here, we show that Dazl translationally...
Abstract Primordial follicles, a finite reservoir of eggs in mammalian ovaries, are composed single oocyte and its supporting somatic cells, termed granulosa cells. Although their formation may require reciprocal interplay between oocytes pre-granulosa precursors little is known about the underlying mechanisms. We addressed this issue by decoding transcriptome cells during primordial follicles. found that marked gene expression changes, including extracellular matrix, cell adhesion, several...
Monolayer assemblies ofsome phthalocyanine derivatives with a central conjugated system surrounded by an insulating region of eight alkyl substituents have been produced, and their molecular orientation electrical behaviour studied. Polarized visible IR spectra for the multilayers deposited horizontal lifting method showed that macrocycles were nearly parallel to surface hydrocarbon chains oriented almost vertically. The perpendicular conductivity was ca. 10–13 S cm–1, while value 10–7 cm–1....
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Ultraviolet photoelectron spectroscopy (UPS) has been applied to the investigation of electronic structure oligothiophenes with 4-8 thiophene ring. In a series α-linked oligomers (αn, number rings n = 4-8), systematic evolution π band forming levels are observed in region 0.7-3eV below Fermi level (EF) and bandwidth becomes broader n. The non-bonding is at 3.5eV EF its energy almost independent UPS spectra α7 α8 fairly similar polythiophene, showing that these good model compounds polymer....
Effects of metal surfaces, such as aluminium, silver and gold, on the melting behavior thermal polymerization long-chain diynoic acids having a diacetylene group at different positions were investigated by analyses using DSC, TG other methods. The surface effects metals significant in order Ag, Al Au. These are attributable to anchoring carboxyl chemisorption, which leads unfavorable condition for heptadeca-2,4-diynoic acid. In case tricosa-10,12-diynoic acid, containing flexible methylene...
ABSTRACT Monolayers of europium complexes on water surface have been directly visualized in the gas-liquid expanded region at different temperatures using Brewster angle microscopy (BAM). The film texture with network patterns complex (C18)2 Eu(DBM)4 and hs evolution time temperature subphase were examined. average linear cell dimension polygon areas analyzed as a function temperature. mechanism domain growth is qualitatively discussed.