- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Gastric Cancer Management and Outcomes
- Assisted Reproductive Technology and Twin Pregnancy
- Demographic Trends and Gender Preferences
- Historical Economic and Social Studies
- Birth, Development, and Health
- Family Dynamics and Relationships
- Gastrointestinal Tumor Research and Treatment
- Advanced Causal Inference Techniques
- Colorectal Cancer Screening and Detection
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Colorectal Cancer Surgical Treatments
- Cognitive Abilities and Testing
- Global Maternal and Child Health
- Trauma and Emergency Care Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Global Maritime and Colonial Histories
- Radiation Dose and Imaging
Lund University
2012-2025
Helsingborgs lasarett
2018-2024
Skaraborg Hospital
2022
University of Gothenburg
2011-2021
Skåne University Hospital
2018
Foundation for Human Potential
2007
University of Southern California
1996-2003
Universidad de Granada
1998
Harvard University
1935
Massachusetts General Hospital
1935
Objective The purpose of the study was to test hypothesis that cardiac mucosa, carditis, and specialized intestinal metaplasia at an endoscopically normal-appearing cardia are manifestations gastroesophageal reflux disease. Summary Background Data In absence esophageal mucosal injury, diagnosis disease currently rests on 24-hour pH monitoring. Histologic examination esophagus is not useful. recent identification cardia, along with observation it occurs in inflamed led authors focus type...
To evaluate prospectively the outcome of laparoscopic fundoplication in a large cohort patients with typical symptoms gastroesophageal reflux.The development over past several years has resulted renewed interest surgical treatment reflux disease (GERD).One hundred GERD were studied. The study was limited to positive 24-hour pH studies and "typical" GERD. Laparoscopic performed when clinical assessment suggested adequate esophageal motility length. Outcome measures included relief primary...
Hemospray TM (TC-325) is a novel hemostatic agent licensed for use in nonvariceal upper gastrointestinal bleeding (NVUGIB) Europe.We present the operating characteristics and performance of TC-325 largest registry to date patients presenting with NVUGIB everyday clinical practice.Prospective anonymized data device outcomes were collected from 10 European centers using multicentre SEAL survey (Survey Evaluate Application Luminal tract). was used as monotherapy or second-line therapy...
A series of 71 patients with multiple measured biopsies the gastroesophageal junctional region permitting assessment presence and length different glandular epithelial types is presented. All but nine 53 in whom a 24-hour pH study was performed had abnormal reflux, suggesting that endoscopic recognition an columnar mucosa at junction sufficient to precipitate multiple-level indicates high probability reflux. cardiac (CM) or oxyntocardiac (OCM). CM present 68 patients. The prevalence...
To quantify the occurrence of intestinal metaplasia in columnar-lined esophagus (CLE) during endoscopic surveillance and to evaluate impact antireflux surgery on development metaplasia.The malignant potential segments CLE is mainly restricted those containing metaplasia. Patients with which no can be detected are rarely enrolled a program but may still at increased risk developing esophageal adenocarcinoma because missed or develop time.The biopsy samples was determined repeated endoscopies...
To evaluate the pathogenesis of metaplastic processes within esophagus using a human model in which exact duration reflux was known.The Barrett's (BE) is incompletely understood. Patients undergoing esophagectomy and gastric tube reconstruction represent good for studying pathophysiology columnar cell metaplasia because cervical rarely or never exposed to contents before surgical procedure.Thirty-two patients underwent manometry, simultaneous 24-hour pH bilirubin monitoring, endoscopy with...
Risk factors for the presence and extent of Barrett esophagus (BE) can be identified in patients with gastroesophageal reflux disease (GERD).Case-comparison study.University tertiary referral center.Five hundred two consecutive GERD documented by 24-hour esophageal pH monitoring complete demographic, endoscopic, physiological evaluation, divided groups according to BE (328 without 174 [67 short-segment 107 long-segment BE]).Clinical, data, studied multivariate analysis, identify independent...
To evaluate risk factors for dysplasia and adenocarcinoma development in nondysplastic Barrett mucosa.The patients with esophagus to develop esophageal is low, most undergoing surveillance will not malignancy. Identification of may allow more rational programs which are stratified according their individual progressing invasive adenocarcinoma.The was studied during long-term endoscopic histologic 140 free from dysplasia. Risk progression were evaluated.Median follow-up 5.8 years. Forty-four...
Heller's esophagomyotomy relieves dysphagia but does not restore esophageal peristalsis. The myotomy may induce reflux and the addition of a 360° fundoplication be hazardous with regard to remaining aperistaltic esophagus. aim this prospectively randomized clinical trial was compare outcome for patients uncomplicated achalasia who underwent an anterior (H group) or without additional floppy Nissen + N group). Between 1984 1995, 20 were one other performed operations, 10 per group....
OBJECTIVES Esophageal pH monitoring using a wireless capsule has been suggested to generate less adverse symptoms resulting in improved patient acceptance compared with the catheter-based method although evidence support this assumption is lacking. The aim of study was evaluate and compare subjective experience patients undergoing both techniques for esophageal monitoring. METHODS Using randomized design, referred testing underwent traditional 24-h recording 7-day interval. placed during...
Background: The impact of surgical specialization on long-term survival in patients undergoing emergent colon cancer resections remains unclear. Method: A retrospective analysis was conducted all who underwent at a secondary care hospital between 2010 and 2020. most senior surgeon performing the procedures classified as colorectal (CS) or non-colorectal (NCS). NCS further divided into acute surgeons (ACSs) general (GSs). Overall (OS) cancer-free (CFS) were compared operated by with different...
A new wireless technique for oesophageal pH monitoring has recently been introduced (Bravo®). To implement this in clinical practice, values of normal acid exposure need to be defined a large age- and gender-matched healthy population. The aims study were investigate the feasibility safety establish exposure.
This special issue contains a collection of papers that study how children are affected by their sibship size, using anthropometric data. The varied results provide wealth new knowledge and show this influence is context-specific. In paper I discuss the methodological challenges we will encounter continuing research on resource dilution in families. most important challenge plausible endogeneity size thus biased estimates effect. problem can be made worse through residual confounding caused...