A5033665514- Cardiac electrophysiology and arrhythmias
- Natural Language Processing Techniques
- Ion channel regulation and function
- Topic Modeling
- Protein Structure and Dynamics
- Nonlinear Dynamics and Pattern Formation
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Lung Cancer Research Studies
- Government, Law, and Information Management
- Lung Cancer Diagnosis and Treatment
- Speech and dialogue systems
- Reading and Literacy Development
- Brain Metastases and Treatment
- Statistical Methods in Clinical Trials
- Gene expression and cancer classification
- Molecular Biology Techniques and Applications
- Text Readability and Simplification
- Advanced Radiotherapy Techniques
- Semantic Web and Ontologies
- Smart Cities and Technologies
- Handwritten Text Recognition Techniques
- Single-cell and spatial transcriptomics
- Cardiovascular Function and Risk Factors
- Image Processing and 3D Reconstruction
Vrije Universiteit Brussel
2019-2020
CrossLang (Belgium)
2019
Ghent University
2013-2016
Rotors occurring in the heart underlie mechanisms of cardiac arrhythmias. Answering question whether or not location rotors is related to local properties tissue has important practical applications. This because ablation been shown be an effective way fight In this study, we investigate, silico, dynamics two-dimensional and anatomical model human ventricles using a Ten Tusscher-Noble-Noble-Panfilov (TNNP) for ventricular cells. We study effect small size ionic heterogeneities, similar those...
In relation to cardiac arrhythmias, heterogeneity of tissue is one the most important factors underlying onset spiral waves and determining their type. this paper, we numerically model realistic size value study formation dynamics around such heterogeneity. We find that only sustained pattern obtained a single wave anchored Dynamics an depend on extent heterogeneity, for certain size, abrupt regional increase in period excitation occurring as bifurcation. spatial distribution periods discuss...
Action potential duration (APD) heterogeneity of cardiac tissue is one the most important factors underlying initiation deadly arrhythmias. In many cases such can be measured at level only, while it originates from differences between individual cells. The extent and single cell differ substantially in to know relation them. Here we study effects coupling on APD numerical simulations using ionic TP06 model for human tissue. We show that effect described mathematically a Gaussian Green's...
Abstract The main mechanism of formation reentrant cardiac arrhythmias is via waveblocks at heterogeneities tissue. We report that heterogeneity and the area waveblock can extend itself in space result new additional sources, or termination existing sources arrhythmias. This effect based on a form instability, which we coin as global alternans instability (GAI). GAI closely related to so-called (discordant) however its onset determined by properties APD-restitution curve not slope. relates...
Abstract Current spatial transcriptomics technologies are increasingly able to measure large gene panels at subcellular resolution, but a major bottleneck in this rapidly advancing field is the computational analysis and interpretation of data. To bridge gap, here we present SPArrOW, flexible, modular scalable pipeline for processing SPArrOW improves cell segmentation leads better overall data quality, resulting more accurate annotations single-cell level. Furthermore, it provides users with...
To build state-of-the-art Neural Machine Translation (NMT) systems, high-quality parallel sentences are needed. Typically, large amounts of data scraped from multilingual web sites and aligned into datasets for training. Many tools exist automatic alignment such datasets. However, the quality resulting corpus can be disappointing. In this paper, we present a tool misalignment detection (MAD). We treated task determining whether pair constitutes genuine translation as supervised regression...
ESTRO 37 S489 preferred over PTV-based IMPT.Finally, as this work evaluated only a limited set of parameters, more is needed to evaluate other aspects IMPT for the treatment oropharynx cancer.