A5090252384- Fullerene Chemistry and Applications
- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- RNA Research and Splicing
- Neurotransmitter Receptor Influence on Behavior
- Graphene research and applications
- Boron and Carbon Nanomaterials Research
- Synthesis and Properties of Aromatic Compounds
- RNA modifications and cancer
- COVID-19 and healthcare impacts
- RNA regulation and disease
- Advanced biosensing and bioanalysis techniques
- Porphyrin and Phthalocyanine Chemistry
- Telemedicine and Telehealth Implementation
- Supercapacitor Materials and Fabrication
- Histone Deacetylase Inhibitors Research
- RNA and protein synthesis mechanisms
- Carbon Nanotubes in Composites
- Forensic Toxicology and Drug Analysis
- Memory and Neural Mechanisms
- Advancements in Battery Materials
- Treatment of Major Depression
- Advanced Nanomaterials in Catalysis
- Multiferroics and related materials
- Dendrimers and Hyperbranched Polymers
Peking University
2007-2025
Beijing National Laboratory for Molecular Sciences
2020-2024
Xinjiang University
2024
Huzhou University
2024
Western University
2020-2023
National Institutes for Food and Drug Control
2015-2022
Wuhan University of Technology
2019-2021
Affiliated Hospital of North Sichuan Medical College
2021
University of Florida
2019
Florey Institute of Neuroscience and Mental Health
2015
4-Methylethcathinone is a drug that belongs to the second generation of synthetic cathinones, and recently it has been ranked among most popular "legal highs". Although similar in vitro neurochemical actions other drugs such as cocaine, behavioral effects 4-methylethcathinone remain be determined.The addictive potential locomotor potentiation by were investigated rats using conditioned place preference sensitization paradigm. Methamphetamine was used positive control. Because cathinones can...
An intriguing intermediate state is revealed as a bridge between conventional antiferroelectric and ferroelectric states in PbZrO<sub>3</sub>-based perovskites
The effects of nanoconfined water and the charge storage mechanism are crucial to achieving ultrahigh electrochemical performance two-dimensional transition metal carbides (MXenes). We propose a facile method manipulate through surface chemistry modification. By introducing oxygen nitrogen groups, more active sites were created for Ti3C2 MXene, interlayer spacing was significantly increased by accommodating three-layer water. Exceptionally high capacitance 550 F g-1 (2000 cm-3) obtained with...
One amino group of o‐phenylenediamine undergoes nucleophilic addition to the carbonyl moiety an open‐cage fullerene containing a 9‐membered ring orifice. Subsequent intramolecular cyclization under mild conditions generated novel derivative featuring enlarged 12‐membered The unreacted in this adduct could be selectively oxidized form nitroso group, which was subsequently reduced back using hydrochloric acid. This reduction process simultaneously induced dichlorination on adjacent aromatic ring.
A 19-membered open-cage fullerene derivative was prepared from C60 in 7 steps and 5.5 % yield through the peroxide-mediate pathway. There are four carbonyl groups, an ether oxygen a quinoxaline moiety on rim of orifice. chloride anion could be inserted into its cavity by heating with hydrochloric acid at 60 °C for 4 h. Encapsulation fluoride, bromide iodide anions also achieved slightly more forcing conditions, 90 14 Single crystal X-ray structures sodium salt encapsulated derivatives were...
Background In recent years, amphetamine-type stimulants (ATS) have increased dramatically in East-south Asia, especially China. Most ATS users suffered from psychosis comorbidity, and depression is the main syndrome users. Methodology A cross-sectional study of depressive symptoms associated factors among was conducted compulsory voluntary drug detoxification rehabilitation centers Beijing Guangdong Province March, 2010 to August, 2010. Total 402 eligible participants were recruited...
Abstract Aminoacyl-tRNA synthetases are essential enzymes responsible for charging amino acids onto cognate tRNAs during protein synthesis. In histidyl-tRNA synthetase (HARS), autosomal dominant mutations V133F, V155G, Y330C and S356N in the HARS catalytic domain cause Charcot–Marie–Tooth disease type 2 W (CMT2W), while tRNA-binding mutation Y454S causes recessive Usher syndrome IIIB. a yeast model, all human variants complemented genomic deletion of ortholog HTS1 at high expression levels....
Abstract Background Telemedicine is increasingly utilized as an alternative to in person consultation. Current pandemic conditions are providing additional impetus virtual care delivery. We compared both adolescent and caregiver (parent or guardian) attitudes towards telemedicine (here tertiary center remote health location) a crucial determinant of longer-term effectiveness. Methods This qualitative research study analyzed transcribed structured telephone interviews with 11–18 year-old...
Objective: To explore the prevalence of human immunodeficiency virus (HIV) and hepatitis C (HCV) risk factors among opiate drug users in Beijing. Methods: The enrolled methadone maintenance treatment clinics Beijing from 30 November 2004 to 31 March 2008 were investigated. blood samples collected tested for HIV HCV infection questionnaires used all subjects admitted. Results: Among 1211 eligible subjects, 12 713 HCV-positive observed; prevalences .99% 58.88%, respectively. Young age,...
Derangements of trace elements often occur in patients with renal failure and play a crucial role chronic kidney disease. The natural history element deposition worsening disease has been poorly described. Some essential may get wasted (e.g., selenium, zinc, manganese) while other accumulate cobalt, lead, molybdenum, vanadium). Data are most readily available relating to hemodialysis patients. Continuous replacement therapies (for the treatment acute injury) without need for therapy remain...
When a stabilized memory is recalled or reactivated, it becomes labile and sensitive to disruptors such as protein-synthesis inhibitors. Previous evidence demonstrates that stress modulates different aspects of memory. The role during reactivation on rewarding aversive not known, however. This study examines the effects using conditioned place preference aversion paradigm. Rats were trained acquire sucrose cocaine-conditioned naloxone-conditioned aversion. Subsequently, rats reexposed...
Open-cage fullerenes with a quinoxaline moiety on the rim of orifice showed evident π-system extension effect NMR and UV-Vis spectra.
Comprehensive Summary Most of the known open‐cage fullerene derivatives contain carbonyl and other relatively inert groups on rim orifice. It is difficult to rationally design further reactions attach functional these derivatives. In present work, two molecules difunctional 1,4‐benzenediamine have been incorporated into an C 60 derivative through one amino group leaving free for functionalization. The 4‐aminophenol reacted analogously form with a OH each phenyl rings. hydroxyl ring above...
Telemedicine use increased during the COVID-19 pandemic. We compared both adolescent/caregiver attitudes towards telemedicine pre- and intra-pandemic.In a tertiary care setting with large remote catchment area, we conducted qualitative analysis of structured interviews dyads 11 to 18-year-old patients their caregivers using NVivo pandemic findings our previous research [1].We enrolled 14 (35 ± 27 in-person visits 4 3 per participant) these before Adolescents' mean age was 15.2 2.1 years...
Benzylamine selectively adds to one of the two carbonyl groups on 9-membered orifice form an N , O -aminal moiety. Subsequent oxidation and hydrogen atom transfer lead a decarboxylation process formation nor [59]fullerene derivative.
Abstract The chemical reactivity of a 10‐membered diketo open‐cage fullerene C 60 (O) 2 (OO t Bu) 4 was investigated in an effort to reveal the unique reaction pattern derivatives. Selective cleavage peroxo O−O bonds observed under thermolysis presence iodine form epoxy groups around orifice. Opening leads vicinal diol moiety, oxidation which resulted new keto‐lactone derivative. Single crystal X‐ray diffraction analysis showed that size rectangular orifice is 2.96×4.66 Å.