Tianfu Wen

ORCID: 0000-0003-1979-9775
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Research Areas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver Disease Diagnosis and Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Liver Disease and Transplantation
  • Cancer Mechanisms and Therapy
  • Organ Transplantation Techniques and Outcomes
  • Pancreatic and Hepatic Oncology Research
  • Inflammatory Biomarkers in Disease Prognosis
  • Renal cell carcinoma treatment
  • Congenital Anomalies and Fetal Surgery
  • Lung Cancer Research Studies
  • Parasitic infections in humans and animals
  • Cancer, Lipids, and Metabolism
  • Hepatitis B Virus Studies
  • Parasitic Infections and Diagnostics
  • Liver physiology and pathology
  • MRI in cancer diagnosis
  • Healthcare cost, quality, practices
  • Ferroptosis and cancer prognosis
  • Biliary and Gastrointestinal Fistulas
  • Healthcare Systems and Challenges
  • Antifungal resistance and susceptibility
  • Posttraumatic Stress Disorder Research
  • Aortic Disease and Treatment Approaches
  • Transplantation: Methods and Outcomes

West China Hospital of Sichuan University
2014-2025

Sichuan University
2014-2025

Endocrinology Research Center
2017

National Natural Science Foundation of China
2015

Central South University
2009

Second Xiangya Hospital of Central South University
2009

Ex vivo liver resection combined with autotransplantation is a recently introduced approach to cure end-stage hepatic alveolar echinococcosis (HAE), which considered unresectable by conventional radical due echinococcal dissemination into the crucial intrahepatic conduits and adjacent structures. This article aims discuss manipulation details propose reasonable indications for this promising technique. All patients successfully underwent no intraoperative mortality. The median weight of...

10.1111/ajt.14621 article EN cc-by-nc American Journal of Transplantation 2017-12-12

According to the Barcelona Clinic Liver Cancer (BCLC) guidelines, transarterial chemoembolization (TACE) is recommended for BCLC stage B hepatocellular carcinoma (HCC). However, an investigation of use resection needed. Therefore, we compared efficacy and safety hepatic (HR) with that TACE in treating intermediate HCC. We retrospectively enrolled 923 patients HCC who underwent (490 cases) or HR (433 cases). The baseline characteristics, postoperative recoveries, long-term overall survival...

10.1097/md.0000000000000180 article EN cc-by-nc Medicine 2014-12-01

Objective The aim of this study was to investigate appropriate treatment strategies for recurrent intrahepatic hepatocellular carcinoma (HCC) in patients who fulfilled the Milan criteria at primary hepatectomy. Patients and methods A total 124 underwent curative-intent resection HCC our center between January 2007 March 2014 were retrospectively enrolled; had initially criteria, but developed recurrence. Seventy-four transarterial chemoembolization (TACE) another 50 repeat (RR) or...

10.1097/meg.0000000000000383 article EN European Journal of Gastroenterology & Hepatology 2015-05-01

Combinations of transarterial chemoembolization (TACE) and radical therapies (pretransplantation, resection radiofrequency ablation) for hepatocellular carcinoma (HCC) have been reported as controversial issues in recent years. A consecutive sample 1560 patients with Barcelona Clinic Liver Cancer (BCLC) stage A/B HCC who underwent solitary Radiofrequency ablation (RFA), or liver transplantation (LT) adjuvant pre-operative TACE were included. The 1-, 3- 5-year overall survival rates...

10.1038/srep41624 article EN cc-by Scientific Reports 2017-02-03

ABSTRACT Background Hepatocellular carcinoma (HCC) is the second leading cause of cancer‐related death in China. The rapid progress systemic therapies has led to approval many therapeutic methods that have quickly changed clinical guidelines and practices. Because high heterogeneity HCC, there are still some gaps between real‐world practice. present study surveyed experts China investigate current treatment concepts practice regarding HCC. Methods A questionnaire survey on HCC was...

10.1002/cai2.70006 article EN cc-by Cancer Innovation 2025-04-07

The prognosis of patients with hepatocellular carcinoma (HCC) after curative resection varies greatly. Few studies had investigated the risk factors for early recurrence (recurrence-free time ≤ 1 year) hepatitis B virus (HBV)-related HCCs meeting Milan criteria.A retrospective analysis was performed on 224 HCC criteria who underwent liver in our center between February 2007 and March 2012. overall survival (OS) rate, recurrence-free (RFS) rate were analyzed.After a median follow-up 33.3...

10.7314/apjcp.2013.14.12.7101 article EN cc-by Asian Pacific Journal of Cancer Prevention 2013-12-31

Aim: As high gamma-glutamyltransferase level or low albumin had negative impact on the prognosis of hepatocellular carcinoma (HCC), prognostic role to ratio (AGR) in patients underwent hepatectomy remains unclear. Methods: Between January 2007 and December 2015, 1143 HCC after were reviewed from a prospectively maintained database West China Hospital. All qualified patients(n=959) classified as training set (year 2007-2012, n=480) validation 2012-2017, n=479). Time‐dependent receiver...

10.3389/fonc.2019.00817 article EN cc-by Frontiers in Oncology 2019-09-04

The effect of preoperative transcatheter arterial chemoembolization (TACE) on the short- and long-term outcome resectable hepatocellular carcinoma (HCC) is controversial. We conducted a retrospective evaluation this aspect using data from our center.A total 656 consecutive patients who underwent curative resection HCC were divided into two groups based TACE: liver (LR) group (405 cases) TACE-LR (183 cases). Overall disease-free survival curves constructed Kaplan-Meier method compared with...

10.1016/s1665-2681(19)30846-4 article EN cc-by-nc-nd Annals of Hepatology 2014-07-01

Abstract There is little information concerning the predictive ability of preoperative platelet to albumin ratio (PAR) in hepatocellular carcinoma (HCC) patients after liver resection. In current study, we aimed assess prognostic power PAR HCC without portal hypertension (PH) following Approximately 628 were included this study. A receiver operating characteristic (ROC) curve analysis was performed evaluate value for both recurrence-free survival (RFS) and overall (OS). Univariate...

10.1097/md.0000000000017920 article EN cc-by-nc Medicine 2019-11-01

Background. Living donor liver transplantation (LDLT) for patients with high model end-stage disease (MELD) scores is controversial due to its poor outcome. However, there little information regarding which factor would negatively impact the outcome of MELD scores. The aim this study was identify factors associated in-hospital mortality after LDLT. Material and methods. All an ≥ 20 who received LDLT from 2005 2011 were recruited present study. Pre-and intra-operative variables...

10.1016/s1665-2681(19)31460-7 article EN cc-by-nc-nd Annals of Hepatology 2012-07-01

Background: This retrospective study aimed to validate the safety and effectiveness of hepatectomy for huge hepatocellular carcinoma (HCC). Materials Methods: Data patients who underwent HCC between January 2006 December 2012 were reviewed. The divided into three groups: HCC(<TEX>${\geq}10cm$</TEX> in diameter), large HCC(<TEX>${\geq}5$</TEX> but<10 cm diameter) small HCC(<5cm diameter). Results: Characteristics pre-operative all groups homogeneously distributed except alpha fetal protein...

10.7314/apjcp.2014.15.17.7069 article EN cc-by Asian Pacific Journal of Cancer Prevention 2014-09-15

Treatments about small hepatocellular carcinoma (HCC) and hypersplenism associated with good hepatic reserve are not well established. The aim of this study was to investigate the outcome synchronous hepatectomy splenectomy for those patients.Splenomegaly were defined as a pathological spleen. Seven hundred fifty-six patients HCC (381 spleen, 375 without spleen) divided into three groups. One ten 381 underwent (group A), 271 alone (Group B) spleen C).The influence different treatments...

10.18632/oncotarget.17758 article EN Oncotarget 2017-05-10
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