A5068961095- Phytochemistry and Biological Activities
- Multicomponent Synthesis of Heterocycles
- Natural Antidiabetic Agents Studies
- Essential Oils and Antimicrobial Activity
- Synthesis and biological activity
- Natural product bioactivities and synthesis
- Chemical Synthesis and Analysis
- Synthesis and Reactions of Organic Compounds
- Bioactive natural compounds
- Phytochemicals and Antioxidant Activities
- Synthesis of Organic Compounds
- Synthesis of heterocyclic compounds
- Synthesis and Biological Evaluation
- Ethnobotanical and Medicinal Plants Studies
- Inorganic and Organometallic Chemistry
- Nanoparticles: synthesis and applications
- Fungal Biology and Applications
- Natural Products and Biological Research
- Plant chemical constituents analysis
- Chemical synthesis and alkaloids
- Click Chemistry and Applications
- Chemical Synthesis and Reactions
- Carbon and Quantum Dots Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Computational Drug Discovery Methods
Tishk International University
2018-2025
Salahaddin University-Erbil
2003-2017
University of Manchester
1985
AbstractThe major enzyme responsible for the hydrolytic breakdown of neurotransmitter acetylcholine (ACh) is acetylcholinesterase (AChE). Acetylcholinesterase inhibitors (AChEIs) are most prescribed class medications treatment Alzheimer's disease (AD) and dementia. The limitations available therapy, like side effects, drug tolerance, inefficacy in halting progression, drive need better, more efficacious, safer drugs. In this study, a series fourteen novel chalcone-coumarin derivatives (8a-n)...
In this work, zinc oxide (ZnO) thin film has been assembled through the spin‐coating method and accumulated on p‐type silicon (100) wafer. The ZnO nanoparticles (NPs) prepared via an entirely green procedure using Punica granatum (pomegranate) juice extract as efficient chelating capping agent. coated NPs exhibited a homogeneous over crystal structure, surface morphology, alignment, optical characteristics of were studied X‐ray diffraction, field‐emission scanning electron microscopy, EDX...
In this work, a series of novel 3-amino-4H-thieno[3,2-c]coumarins were designed and synthesized by one-pot, catalyst-free, three-component reaction 3-acetylcoumarins with amines elemental sulfur. Readily available starting materials, simple heating conditions, facile installation sulfur atom into the molecule using S8 as source, acceptable functional group tolerance, synthetically useful yields are some highlighted benefits process.
This article aims to contribute the limited literature on traditional gastronomic knowledge concerning acorn-based bread by ethnographically documenting ingredients, preparation techniques and consumption practices of baked goods made from acorn seeds flour that are still used today or at least present in living memory. A qualitative comparative case method was adopted, ethnographic data were gathered 67 people six selected Mediterranean, Central Asian Middle Eastern countries. The analysis...
In this investigation, the extract of Rhus coriaria utilized for preparation Fe3O4 nanoparticle using a green approach. This method is clean, non-toxic and eco-friendly. The synthesized nano-catalyst was described by means SEM, EDX, elemental-mapping point exploration, X-ray diffraction, FT-IR, UV-Vis analysis methods. biosynthesized magnetite nanoparticles are affordable reusable. Accordingly, allows catalyst to be in synthesizing some new 2-naphthol bis-Betti bases condensation substituted...
ABSTRACT Biebersteinia multifida DC. is a wild therapeutic plant, traditionally used for various medicinal applications. The aim of the present study to extract bioactive constituents from plants' roots and synthesize copper nanoparticles (CuNPs). Ethanolic extraction plant's yielded 19 compounds, recognized through gas chromatography–mass spectroscopy (GC‐MS), mainly including citraconic anhydride, γ‐sitosterol, 2‐furancarboxaldehyde. prepared CuNPs have been fully characterized. biological...
Background and objective: Isoxazoles are significant heterocyclic products that used in various applications the field of medicinal chemistry. Along with prescription drugs, a variety bioactive pharmaceutical substances, such as valdecoxib, leflunomide, danazol, include isoxazole core. The present work aimed to synthesize test antibacterial, antioxidant, antifungal activities combined theoretical investigations. Methods: Various 2,4-disubstituted isoxazoles have been synthesized through...
Herein, we present an efficient method for the synthesis of functionalized 1,6-dihydropyridine derivatives. Readily available precursors, operational simplicity, and synthetically useful yields are some highlighted advantages this transformation.
In remote villages of Kurdistan-Iraq, such as in those on Safeen Mountain, decoctions, potions, and oils from the local herbal tradition have provided only medicinal remedies for centuries, up to today. A variety diseases are treated with different plant preparations, ranging simple rheumatism diarrhea, skin diseases, highly complicated kidney heart problems. This survey describes, first time, mostly used plants, resulting several interviews healers. The bioactivity some isolated compounds...
A dozen Iris species (Iridaceae) are considered traditional remedies in Kurdistan, especially for treating inflammations. Phytochemical studies still scarce. The information reported the literature about growing Kurdistan has been summarized first part of this paper, although, except persica, investigations have performed on vegetal samples collected countries different from Kurdistan. In second work, we investigated, time, contents methanolic extracts postii aerial parts and rhizomes that...
Abstract This work demonstrates the design and straightforward syntheses of several novel probe-based on rhodamine B 2-mercaptoquinoline-3-carbaldehydes as a naked-eye colorimetric probe, indicating sensitive selective recognition towards nickel (II) with limit detection 0.30 μmol L −1 (0.02 mg ). Further, by employing oxidation property hypochlorite (OCl − ), this probe parallelly has been deployed to detect in laboratory conditions 0.19 mL living cells. Regarded negligible cell toxicity...
The majority of Kurds inhabit a region that includes adjacent parts Iran, Iraq, Syria and Turkey. This review shows the traditional medicine is still used by Kurdish peoples underlines medicinal value great number plants locally. uses include treatment variety diseases, ranging from simple stomach-ache to highly complicate male female disorders; even sexual weakness kidney stones are treated plants. for curing gastro-intestinal disorders inflammation, followed urinary tract disorders, skin...
Abstract Alzheimer is a deadly neurodegenerative disease that commonly attacks elderly people around the world. Therefore, this has drawn attention among researchers to find new potent drugs treat (AD) more efficiently. Coumarin containing scaffold potential AD agent. hybrids are frequently used as template design novel therapeutic agent for treatment of AD, which designed based on using molecular docking. As result docking studies shown coumarin cores can occupy PAS by making extensive...
An organized biofunctional characterization of red, black, and white ginseng root extracts fractions was performed. To assess antioxidant, antiglycation, enzyme inhibitory, antiamnestic, cytotoxic, thrombolytic, antibiofilm potentials in roots three Panax preparations (red, white), powdered material extracted fractionated into different solvents. Antioxidant activity, phenolic flavonoids contents were assessed by using free radical scavenging, Folin–Ciocalteu reagent aluminum chloride...
Traditional medicine is still widely practiced in Iraqi Kurdistan, especially by people living villages on mountainous regions; medicinal plants are also sold the markets of large towns, such as at Erbil, capital Kurdistan Autonomous Region. About a dozen Verbascum species (Scrophulariaceae) commonly employed Kurdish traditional medicine, for treating burns and other skin diseases. However, isolation bioactive secondary metabolites from these has not been subject intense scientific...
Abstract The volatile fractions isolated from Prangos peucedanifolia Fenzl leaves and flowers were investigated for their phytochemical composition biological properties. Flower leaf hydrodistillation afforded 3.14 0.49 g of yellowish oils in 1.25 0.41% yields, respectively, dry vegetable materials. According to the GC‐FID GC/MS analyses, 36 (99.35% total oil composition) 26 compounds (89.12%) identified two oils, respectively. major constituents flower fraction β ‐pinene (35.58%), α...
In this research, we synthesized new pyrimidine fused quinoline derivatives in high yields using multicomponent reaction of the 2-amino-4-hydroxyacetophenone, isopropenylacetylene, aldehydes, malononitrile or ethyl cyanoacetate, acetaldehyde and dimethylacetylene dicarboxylate presence catalytic amounts Fe3O4/KF/Clinoptilolite@MWCNTs magnetic nanocomposites ionic liquid as green solvent at room temperature. Also, activity MNCs was evaluated reduction organic pollutants such 4-nitrophenol...
The secondary metabolites produced by Tricholoma ustaloides Romagn., a mushroom species belonging to the large genus (Basidiomycota, Tricholomataceae), are unknown. Therefore, encouraged interesting results obtained in our previous chemical analyses of few collected Italian woods, we aimed investigate ustaloides. analysis involved isolation and characterization through an extensive chromatographic study. structures isolated metabolites, including absolute configuration, were established...
Abstract Amorphous nitrogen‐doped carbon dots (a‐N‐CDs) have been obtained under hydrothermal conditions from citric acid and diethylenetriamine (DETA) as the nitrogen source, respectively. Such materials exhibit a significant absorption in visible light region successfully employed photoredox catalyst violet LED irradiation for 1,2‐difunctionalization of olefins via an atom transfer radical addition (ATRA) process. The reported approach occurs smoothly metal‐free aqueous medium, showcasing...
Produced zinc oxide nanoparticles utilizing Anethum graveolens extract has used for the preparation of 1 H -pyrazolo[1,2- a ]pyridazine-5,8-diones under solvent-free conditions and at 70 °C through three-component condensation reaction.