A5065535915- EEG and Brain-Computer Interfaces
- Face Recognition and Perception
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Epilepsy research and treatment
- Neurological disorders and treatments
- Visual perception and processing mechanisms
- Neuroscience and Neural Engineering
- Neuroscience and Neuropharmacology Research
- Parkinson's Disease Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Neurobiology of Language and Bilingualism
- Advanced MRI Techniques and Applications
- Balance, Gait, and Falls Prevention
- Neurosurgical Procedures and Complications
- Advanced Neuroimaging Techniques and Applications
- Pharmacological Effects and Toxicity Studies
- Cerebral Palsy and Movement Disorders
- Facial Nerve Paralysis Treatment and Research
- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- Fetal and Pediatric Neurological Disorders
- Face recognition and analysis
- Neurofibromatosis and Schwannoma Cases
- Intracranial Aneurysms: Treatment and Complications
Université de Lorraine
2014-2025
Centre National de la Recherche Scientifique
2009-2025
Centre Hospitalier Régional et Universitaire de Nancy
2015-2024
Ingénierie Moléculaire et Physiopathologie Articulaire
2024
Centre de Recherche en Automatique de Nancy
2009-2023
Inserm
2010-2023
Développement, Adaptation et Handicap
2013-2022
Centre de Médecine Préventive
2017-2020
Evolution des Régulations Endocriniennes
2013-2015
Montreal Neurological Institute and Hospital
2009-2010
Significance Understanding the neural basis of face perception, arguably most important visual function for human social ecology, is utmost importance. With an original fast periodic stimulation approach, we provide a comprehensive quantification selective brain responses to faces throughout ventral stream with direct recordings in gray matter. Selective are distributed whole occipito-temporal cortex, right hemispheric and regional specialization supporting two decades indirect activity...
Significance The left ventral occipito-temporal cortex (VOTC) is a critical part of the reading circuitry. We made measurements with intracerebral electrodes in 37 participants to understand whether this region contains functionally separated brain loci for processing letters and words. Letter-selective responses are found much VOTC. Responses word forms absent posterior VOTC but present intermingled letter-specific anterior results inconsistent hierarchical model which regions uniquely...
In-vivo measurements of human brain tissue conductivity at body temperature were conducted using focal electrical currents injected through intracerebral multicontact electrodes. A total 1,421 in 15 epileptic patients (age: 28 ± 10) a radiofrequency generator (50 kHz current injection) analyzed. Each contact pair was classified as being from healthy (gray matter, n = 696; white 530) or pathological (epileptogenic zone, 195) neuroimaging analysis the local environment and EEG recordings....
Summary Objective Delineation of the epileptogenic zone ( EZ ) in refractory epilepsy related to malformations cortical development MCDs often requires intracranial electroencephalography EEG) recordings, especially cases negative magnetic resonance imaging MRI) or discordant MRI and video‐ EEG findings. It is therefore crucial promote noninvasive methods such as electrical source ESI ). We aimed (1) analyze localization concordance derived from interictal discharges estimated by stereo‐EEG...
Parkinson's disease (PD), the most common basal ganglia degenerative disease, affects balance control, especially when patients change strategy during postural tasks. Bilateral chronic stimulation of subthalamic nucleus (STN) is therapeutically useful in advanced PD, and reduces motor signs patients. Nevertheless, effects STN on control are still debatable.To assess impact bilateral PD to determine how related sensorimotor modifications act neurosensorial organisation programming.Twelve...
Background Occipital nerve stimulation (ONS) has been proposed to treat chronic medically-intractable cluster headache (iCCH) in small series of cases without evaluation its functional and emotional impacts. Methods We report the multidimensional outcome a large observational study iCCH patients, treated by ONS within nationwide multidisciplinary network ( https://clinicaltrials.gov NCT01842763), with one-year follow-up. Prospective was performed before surgery, then three 12 months after....
Human face perception requires a network of brain regions distributed throughout the occipital and temporal lobes with right hemisphere advantage. Present theories consider this as either processing hierarchy beginning inferior gyrus (occipital area; IOG-faces/OFA) or multiple-route nonhierarchical components. The former predicts that removing IOG-faces/OFA will detrimentally affect downstream stages, whereas latter does not. We tested prediction in human patient (Patient S.P.) requiring...
Abstract The sudden onset of a face image leads to prominent face‐selective response in human scalp electroencephalographic (EEG) recordings, peaking 170 ms after stimulus at occipito–temporal (OT) sites: the N170 (or M170 magnetoencephalography). According widely held view, main cortical source lies fusiform gyrus (FG), whereas posteriorly located inferior occipital (IOG) would rather generate earlier responses. Here, we report neural responses upright and inverted faces recorded unique...
Abstract BACKGROUND The exploration of the insula in pre-surgical evaluation epilepsy is considered to be associated with a high vascular risk resulting an incomplete insular cortex. OBJECTIVE To report retrospective observational study using stereoelectroencephalography (sEEG) transopercular and parasagittal oblique intracerebral electrodes from January 2008 2016. first purpose this was evaluate surgical risks cortex sEEG exploration. second define ability placing contacts whole METHODS...
Brain regions located between the right fusiform face area (FFA) in middle gyrus and temporal pole may play a critical role human identity recognition but their investigation is limited by large signal drop-out functional magnetic resonance imaging (fMRI). Here we report an original case who suddenly unable to recognize of faces when electrically stimulated on focal location inside this intermediate region anterior gyrus. The reliable transient deficit occurs without any change percept, even...
Abstract Intracranial EEG (iEEG) is increasingly used in many fields of human cognitive neuroscience since it offers a unique opportunity to directly record brain activity from awake humans at high spatial and temporal resolution. However, little known about the influence reference montage on characteristics iEEG activity. Here, we compare profiles neural for five montages (scalp reference, common average, zero local Bipolar Laplacian) applied large dataset depth electrodes...
The relationship between Blood-Oxygen-Level-Dependent (BOLD) responses in functional magnetic resonance imaging (fMRI) and increases or decreases neural firing rate across human brain regions, especially the association cortex, remains largely unknown. Here, we contrast direct measures of neuronal activity two adjacent regions fusiform gyrus (FG) associated with fMRI (lateral FG portion) (medial same category-selective activity. In both individual brains tested multiple recording sessions, a...
The relationship between Blood-Oxygen-Level-Dependent (BOLD) responses in functional magnetic resonance imaging (fMRI) and increases or decreases neural firing rate across human brain regions, especially the association cortex, remains largely unknown. Here, we contrast direct measures of neuronal activity two adjacent regions fusiform gyrus (FG) associated with fMRI (lateral FG portion) (medial same category-selective activity. In both individual brains tested multiple recording sessions, a...
Abstract
The relationship between Blood-Oxygen-Level-Dependent (BOLD) responses in functional magnetic resonance imaging (fMRI) and increases or decreases neural firing rate across human brain regions, especially the association cortex, remains largely unknown. Here, we contrast direct measures of neuronal activity two adjacent regions fusiform gyrus (FG) associated with fMRI (lateral FG portion) (medial same category-selective activity. In both individual brains tested multiple recording sessions, a...
To define the relationship between epileptogenic zone and polymicrogyric area using intracranial electroencephalography (EEG) recordings in patients with structural epilepsy associated regional infrasylvian polymicrogyria (PMG).We retrospectively reviewed medical charts, scalp, video-EEG recordings, neuroimaging findings, neuropsychological evaluations of four refractory temporal lobe related to PMG who consequently underwent resective surgery.High-resolution magnetic resonance imaging (MRI)...
Electrical brain stimulation can provide important information about the functional organization of human visual cortex. Here, we report phenomena evoked by a large number (562) intracerebral electrical stimulations performed at low-intensity with depth electrodes implanted in occipito-parieto-temporal cortex 22 epileptic patients. Focal primarily hallucinations various complexities: simple (spot or blob), intermediary (geometric forms), complex meaningful shapes (faces); illusions and...