A5035549790- Prostate Cancer Treatment and Research
- Cancer, Lipids, and Metabolism
- Prostate Cancer Diagnosis and Treatment
- Sexual function and dysfunction studies
- Urinary Bladder and Prostate Research
- Nutritional Studies and Diet
- Hormonal and reproductive studies
- Genital Health and Disease
- Urinary and Genital Oncology Studies
- Cancer, Hypoxia, and Metabolism
- Bladder and Urothelial Cancer Treatments
- Consumer Attitudes and Food Labeling
- Sperm and Testicular Function
- Sexuality, Behavior, and Technology
- Dietary Effects on Health
- Obesity, Physical Activity, Diet
- Phytoestrogen effects and research
- Urologic and reproductive health conditions
- Reproductive Biology and Fertility
- COVID-19 and healthcare impacts
- Sex and Gender in Healthcare
- Sexual Differentiation and Disorders
- Urological Disorders and Treatments
- Cancer Risks and Factors
- COVID-19 Clinical Research Studies
University of Catania
2017-2025
Sapienza University of Rome
2024
European Institute of Oncology
2021-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2023
Zealand University Hospital
2023
Group Health Cooperative
2023
Magna Graecia University
2011
Purpose This study aimed to investigate the effects of ejaculatory abstinence on sperm parameters. Methods analysis was registered in PROSPERO (CRD42023472124). We performed a search PubMed using following text terms: ((“sperm parameters” OR “sperm analysis” [Mesh]) AND (“sperm DNA fragmentation” “DNA (“sexual abstinence” [Mesh] “abstinence”)) and an advanced Scopus terms fragmentation”) (“abstinence”). The parameters that were investigated volume, total motility, progressive concentration,...
Abstract Objective To study the association between insulin receptors (isoforms α and β), growth factor‐1 (IGF1) serine/arginine splicing factor 1 (SRSF‐1) in patients with prostate cancer (PC) diabetes. Materials Methods We retrospectively analyzed data from 368 who underwent surgery for PC or benign prostatic hyperplasia (BPH) 2010 2020 at Department of Urology, University Catania. Tissue microarray slides were constructed they stained androgen receptor (AR), receptor‐α ‐β, IGF1 (IGF1‐R),...
Premature ejaculation is a sexual dysfunction that can impact both men and women. This study aimed to shed light on this condition within cohort as extensive possible. We conducted an online open survey, distributed via social media, proposing questionnaire regarding various aspects including the duration of ejaculatory latency, perceptions premature or delayed ejaculation, well lifestyle psychological sexuality. The comprised 77 questions for male participants 16 female participants, with...
Introduction Historically, medical therapy of BPH has had its foundations in alpha-blockers monotherapy or combination with 5 alpha reductase inhibitors (5-ARIs); particular, two important trials (COMBAT and MTOPS) have demonstrated the pivotal role instead individuated which patients are most likely to benefit from alpha-blockers, 5-ARIs, their combination. However different side effects these drugs, such erectile dysfunction, ejaculatory disorders, loss libido, could affect adherence...
Prostate Cancer (PCa) is still ranked as the first cancer in male population and evidences have suggested an alteration of glycemic lipidic metabolism that are related to its progression prognosis. The aim study investigate associations between enzymes’ expression, especially involved pathway, PCa aggressiveness. We retrospectively analyzed data from 390 patients with or benign prostatic hyperplasia (BPH) at Department Urology, University Catania. Immunohistochemical slides were evaluated...
In this study we aimed to investigate the association between dietary phytoestrogen consumption and prostate cancer in a sample of southern Italian individuals.A population-based case-control on factors was conducted from January 2015 December 2016 single institution municipality Catania, Italy (Registration number: 41/2015). A total 118 histopathological-verified (PCa) cases 222 controls were collected. Dietary data collected by using two food frequency questionnaires.Patients with PCa...
In patients affected by high-risk nonmuscle invasive bladder cancer (HR-NMIBC) progression to muscle status is considered as the main indicator of local treatment failure. We aimed investigate effect and time on overall survival (OS) their validity surrogate endpoints.
Prostate cancer (PCa) is a disease with wide range of clinical manifestations. Up to the present date, genetic understanding patients favorable or unfavorable prognosis gaining interest for giving appropriate tailored treatment. We aimed investigate changes associated lymph node metastasis in cohort hormone-naïve Pca patients.We retrospectively analyzed data from 470 who underwent surgery PCa between 2010 and 2020 at Department Urology, University Catania. Inclusion criteria were extra...
BACKGROUND: Prostate cancer (PCa) is a significant health concern, and its incidence prevalence are influenced by various lifestyle factors, including diet. In recent years, the Mediterranean diet has gained popularity due to potential benefits associations with reduced risk for diseases. However, impact of on PCa remains topic debate. OBJECTIVE: The aim this study was test association between adherence severity. METHODS: Background, clinical dietary information (from food frequency...
Augmented adiposity may negatively impact sexual sphere through its metabolic effects and detrimental on reproductive hormones. Moreover, a dysregulated pathway promote apoptosis among spermatogenic cells. Based these premises, relation between weights loss ameliorate semen parameters seems beneficial. To investigate if physical activity affect fertility rate, systematic literature search major dataset has been performed.
Objective: The management of chronic prostatitis/ pelvic pain syndrome type III (CP/CPPS) has been always considered complex due to several biopsychological factors underlying the disease. In this clinical study, we aimed evaluate efficacy treatment with Palmitoylethanolamide, Epilobium and Calendula extract in patients CP/CPPS III.Materials methods: From June 2023 July 2023, enrolled 45 consecutive affected by three different institution. We included aged between 18 75 years symptoms for 3...
In this study, we aimed to identify prognostic factors of cancer mortality in patients who received radical cystectomy and genomic alterations a sub-cohort with locally advanced (pT3-4) and/or positive lymph nodes bladder (BC).We collected 101 BC samples from 2010 2018 previously cystectomy. Immunohistochemical slides were evaluated for PPAR, cAMP, IMP3, Ki67, CDK4, POU5F1, Cyclin E MDM2, p65, CD3, CD4, CD8, CD20, CD68, CD163, FOXP3, PD-1 PD-L1 expression. We calculated score (PS) based on...
We aimed to analyze the association between CYP7B1 and prostate cancer, along with its proteins involved in cancer metabolic processes. A retrospective analysis was performed on 390 patients (PC) or benign prostatic hyperplasia (BPH). investigated interactions expression associated PC processes, followed by an of risk biochemical recurrence based expression. Of 139 elevated expression, 92.8% had cancer. Overall, no increased However, a non-diabetic subgroup analysis, higher indicated...