A5030586813- Vascular Malformations and Hemangiomas
- Tumors and Oncological Cases
- Vascular Malformations Diagnosis and Treatment
- Cancer and Skin Lesions
- Vascular Tumors and Angiosarcomas
- Parvovirus B19 Infection Studies
- Ear and Head Tumors
- Genetic and rare skin diseases.
- Teratomas and Epidermoid Cysts
- Autoimmune Bullous Skin Diseases
- Soft tissue tumor case studies
- Histiocytic Disorders and Treatments
- Oral and Maxillofacial Pathology
- Eosinophilic Disorders and Syndromes
- Congenital Ear and Nasal Anomalies
- Urologic and reproductive health conditions
- Drug-Induced Adverse Reactions
- Immunodeficiency and Autoimmune Disorders
- Sarcoma Diagnosis and Treatment
- Nail Diseases and Treatments
- Autoimmune and Inflammatory Disorders
- Central Venous Catheters and Hemodialysis
- Urticaria and Related Conditions
- Spinal Hematomas and Complications
- Spinal Dysraphism and Malformations
Driscoll Children's Hospital
2025
Texas Children's Hospital
2011-2024
Baylor College of Medicine
2013-2024
UCLouvain
2017
de Duve Institute
2017
Center for Human Genetics
2017
Boston Children's Hospital
2014-2015
Medical College of Wisconsin
2012
University of Kansas Medical Center
2012
Garrahan Hospital
2012
OBJECTIVES. Infantile hemangiomas often are inapparent at birth and have a period of rapid growth during early infancy followed by gradual involution. More precise information on could help predict short-term outcomes make decisions about when referral or intervention, if needed, should be initiated. The objective this study was to describe characteristics infantile hemangioma compare with patterns. METHODS. A prospective cohort involving 7 tertiary care pediatric dermatology practices...
OBJECTIVES. Infantile hemangiomas are the most common tumor of infancy. Risk factors for complications and need treatment have not been studied previously in a large prospective study. This study aims to identify clinical characteristics associated with therapeutic intervention. PATIENTS AND METHODS. We conducted cohort at 7 US pediatric dermatology clinics consecutive sample 1058 children, aged ≤12 years, infantile enrolled between September 2002 October 2003. A standardized questionnaire...
A subgroup of patients with infantile hemangiomas have associated structural anomalies the brain, cerebral vasculature, eyes, sternum, and/or aorta in neurocutaneous disorder known as PHACE syndrome. The diagnosis has been broadly inclusive by using a case definition facial hemangioma plus >or=1 extracutaneous features, leading to numerous reports potential disease many uncertain significance. This consensus statement was thus developed establish diagnostic criteria for syndrome.A...
Infantile hemangiomas (IHs) are the most common tumors of childhood. Unlike other tumors, they have unique ability to involute after proliferation, often leading primary care providers assume will resolve without intervention or consequence. Unfortunately, a subset IHs rapidly develop complications, resulting in pain, functional impairment, permanent disfigurement. As result, clinician has task determining which lesions require early consultation with specialist. Although several recent...
Most arteriovenous malformations (AVMs) are localized and occur sporadically. However, they also can be multifocal in autosomal-dominant disorders, such as hereditary hemorrhagic telangiectasia capillary malformation (CM)-AVM. Previously, we identified RASA1 mutations 50% of patients with CM-AVM. Herein studied non-RASA1 to further elucidate the pathogenicity CMs AVMs.We conducted a genome-wide linkage study on CM-AVM family. Whole-exome sequencing was performed 9 unrelated families. We...
PHACE (OMIM no. 606519) is a neurocutaneous syndrome that refers to the association of large, plaque-like, "segmental" hemangiomas face, with one or more following anomalies: posterior fossa brain malformations, arterial cerebrovascular anomalies, cardiovascular eye and ventral developmental defects, specifically sternal defects and/or supraumbilical raphe. The etiology pathogenesis unknown, potential risk factors for have not been systematically studied. purpose this study was thus...
This study was conducted to determine the prevalence of posterior fossae brain, arterial anomalies, cardiac and eye anomalies (PHACE) in infants with large facial hemangiomas. The extracutaneous manifestations PHACE may be associated significant morbidity, patients hemangiomas has not previously been reported.A multicenter prospective 108 who had were systematically evaluated for PHACE. its this cohort calculated. relationship between hemangioma distribution analyzed.Thirty-three (31%)...
<h3>BACKGROUND AND PURPOSE:</h3> Cerebral and cervical arterial abnormalities are the most common non-cutaneous anomaly in PHACE syndrome, but location type of lesions that occur have not been systematically assessed a large cohort. Our aim was to characterize phenotypic spectrum arteriopathy, assess frequency with which different arteries involved, evaluate spatial relationships between brain structural lesions, hemangiomas syndrome. <h3>MATERIALS METHODS:</h3> Intracranial MRA and/or CTA...
Abstract Propranolol is a non‐selective beta‐adrenergic antagonist successfully used in case of kaposiform hemangioendothelioma (KHE) associated with Kasabach–Merritt phenomenon (KMP). We report 11 patients treated propranolol for KHE and the related variant tufted angioma (TA), six whom also had KMP. The varied responses to treatment, only 36% responding our series, demonstrate need further study this medication before routine use these indications. Pediatr Blood Cancer 2012; 59: 934–938. ©...
Abstract: Multiple cutaneous infantile hemangiomas have been associated with hepatic hemangiomas. Screening of infants five or more abdominal ultrasound is often recommended. The aim this study was to determine the frequency which occur in compared those one four and characterize clinical features these A multicenter prospective children conducted at pediatric dermatology clinics Hemangioma Investigator Groups sites United States, Canada, Spain between October 2005 December 2008. Data were...
Abstract The objective of this retrospective study patients evaluated between J uly 2008 and O ctober 2011 in seven pediatric dermatology centers was to combine collective clinical experience using oral propranolol therapy 32 infants with PHACE syndrome ( P osterior fossa [brain malformations present at birth], H emangioma [usually covering a large area the skin head or neck >5 cm]; A rterial lesions [abnormalities blood vessels head]; C ardiac abnormalities aortic coarctation heart that...
ObjectiveTo develop consensus on diagnostic criteria for LUMBAR syndrome, the association of segmental infantile hemangiomas that affect Lower body with Urogenital anomalies, Ulceration, spinal cord Malformations, Bony defects, Anorectal malformations, Arterial anomalies and/or Renal anomalies.Study designThese were developed by an expert multidisciplinary and multi-institutional team based analysis peer-reviewed data, followed electronic-Delphi a panel 61 international pediatric...