A5032801974- Glioma Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Epilepsy research and treatment
- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Fetal and Pediatric Neurological Disorders
- Neurological disorders and treatments
- Pharmacological Effects and Toxicity Studies
- Neurofibromatosis and Schwannoma Cases
- Spinal Dysraphism and Malformations
- Traumatic Brain Injury and Neurovascular Disturbances
- Spinal Fractures and Fixation Techniques
- Vagus Nerve Stimulation Research
- Neonatal and fetal brain pathology
- EEG and Brain-Computer Interfaces
- Cancer, Hypoxia, and Metabolism
- Pituitary Gland Disorders and Treatments
- Neurogenesis and neuroplasticity mechanisms
- Neural dynamics and brain function
- Neuroblastoma Research and Treatments
- Cervical and Thoracic Myelopathy
- Teratomas and Epidermoid Cysts
- Central Venous Catheters and Hemodialysis
- Brain Metastases and Treatment
UCSF Benioff Children's Hospital
2015-2025
University of California, San Francisco
2015-2025
Neurological Surgery
2015-2025
Statistical Research (United States)
2024
Creative Commons
2021
Barrow Neurological Institute
2020
University of California San Francisco Medical Center
2017
Life Extension Foundation
2016
Epilepsy Foundation
2014
Boston Children's Hospital
2011-2014
We reported previously that astroglia cultured from aquaporin-4-deficient (AQP4-/-) mice migrate more slowly in vitro than those wild-type (AQP4+/+) (J. Cell Sci. 2005;118, 5691-5698). Here, we investigate the migration of fluorescently labeled AQP4+/+ and AQP4-/- after implantation into mouse brains which directional movement was stimulated by a planar stab wound 3 mm away axis injection needle. Two days cell determined location, elongation ratio, orientation cells. Migration but not cells...
Hydrocephalus is caused by an imbalance in cerebrospinal fluid (CSF) production and absorption, resulting excess ventricular accumulation neurologic impairment. Current therapy for hydrocephalus involves surgical diversion of fluid. The water-transporting protein aquaporin-4 (AQP4) expressed at the brain-CSF blood-brain barriers. Here, we provide evidence AQP4-facilitated CSF absorption a transparenchymal pathway into cerebral vasculature. A mouse model obstructive was created injecting...
Attention is a core cognitive mechanism that allows the brain to allocate limited resources depending on current task demands. A number of frontal and posterior parietal cortical areas, referred collectively as fronto-parietal attentional control network, are engaged during allocation in both humans non-human primates. Numerous studies have examined this network human using various neuroimaging scalp electrophysiological techniques. However, little known about how these areas interact...
<h3>BACKGROUND AND PURPOSE:</h3> Cerebral and cervical arterial abnormalities are the most common non-cutaneous anomaly in PHACE syndrome, but location type of lesions that occur have not been systematically assessed a large cohort. Our aim was to characterize phenotypic spectrum arteriopathy, assess frequency with which different arteries involved, evaluate spatial relationships between brain structural lesions, hemangiomas syndrome. <h3>MATERIALS METHODS:</h3> Intracranial MRA and/or CTA...
Abstract Neuromodulation via Responsive Neurostimulation (RNS) or Deep Brain Stimulation (DBS) is an emerging treatment strategy for pediatric drug‐resistant epilepsy (DRE). Knowledge gaps exist in patient selection, surgical technique, and perioperative care. Here, we use expert survey to clarify practices. Thirty‐two members of the Pediatric Epilepsy Research Consortium were surveyed using REDCap. Respondents from 17 centers (missing data one): Four implant RNS only while 13 both DBS....
Treatment of spinal and peripheral nerve lesions relies on localization the pathology by use neurological examination, MR imaging electromyography (EMG)/nerve conduction studies (NCSs). Magnetic resonance neurography (MRN) is a novel technique recently developed for direct nerves. In this study, authors analyzed role MRN in evaluation lesions.Imaging studies, medical records, EMG/NCS results were retrospectively consecutive series 191 patients who underwent disorders at University...
Malformations of cortical development (MCDs) are a major cause medically refractory epilepsy. Our aim was to examine surgical series patients with malformations determine the prognostic factors associated long-term seizure control.We conducted retrospective review 143 MCD who underwent resective surgery for Demographic, imaging, histopathologic, and variables were analyzed potential association freedom. Preoperative magnetic resonance imaging (MRI) evaluated in blind fashion classified...
Intraoperative dorsal column mapping, transcranial motor evoked potentials (TcMEPs), and somatosensory (SSEPs) have been used in adults to assist with the resection of intramedullary spinal cord tumors (IMSCTs) predict postoperative deficits. The authors sought determine whether changes MEP SSEP waveforms would similarly deficits children.The reviewed charts intraoperative records for children who had undergone IMSCTs as well mapping TcMEP monitoring. Motor potential data were supplemented...
Word retrieval is core to language production and relies on complementary processes: the rapid activation of lexical conceptual representations word selection, which chooses correct among semantically related competitors. Lexical measured by semantic priming. In contrast, selection indexed interference hampered in homogeneous (HOM) contexts. We examined spatiotemporal dynamics these processes a picture naming task with blocks heterogeneous (HET) or HOM stimuli. used electrocorticography data...
1Department of Neurological Surgery, Saint Louis University, St. Louis, Missouri; 2Division Pediatric Goryeb Children’s Hospital, Morristown, New Jersey; 3Department Neurosurgery, University Tennessee Health Science Center, and 4Le Bonheur Memphis, Tennessee; 5De part ment Massachusetts General Hos pital, Boston, Massachusetts; 6Department Sur gery, Oregon & Portland, Oregon; 7De Hos pital Pittsburgh, Pennsylvania; 8Division Department Washington School Medicine, Mis souri; 9Department...
OBJECTIVE In children, the repair of skull defects arising from decompressive craniectomy presents a unique set challenges. Single-center studies have identified different risk factors for common complications cranioplasty resorption and infection. The goal present study was to determine bone infection after pediatric cranioplasty. METHODS authors conducted multicenter retrospective case that included all patients who underwent correct defect at 13 centers between 2000 2011 were less than 19...