A5048190391- Spine and Intervertebral Disc Pathology
- Traumatic Brain Injury Research
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Fetal and Pediatric Neurological Disorders
- Cerebrospinal fluid and hydrocephalus
- Sports injuries and prevention
- Diversity and Career in Medicine
- Health and Medical Research Impacts
- Traumatic Brain Injury and Neurovascular Disturbances
- Spinal Dysraphism and Malformations
- Cerebral Venous Sinus Thrombosis
- Thermal Regulation in Medicine
- Craniofacial Disorders and Treatments
- Caveolin-1 and cellular processes
- Surgical Simulation and Training
- Neonatal Respiratory Health Research
- Child Abuse and Related Trauma
- Heat shock proteins research
- Mass Spectrometry Techniques and Applications
- Meta-analysis and systematic reviews
- Nerve injury and regeneration
- Spinal Cord Injury Research
- Intracranial Aneurysms: Treatment and Complications
- IL-33, ST2, and ILC Pathways
University Health Network
2019-2021
Krembil Research Institute
2021
University of Toronto
2021
Augusta University
2019-2020
Icahn School of Medicine at Mount Sinai
2009-2019
Toronto General Hospital
2019
Montefiore Medical Center
2018
Sports Concussion Institute
2018
University of Pittsburgh Medical Center
2018
Touro College
2018
1Department of Neurological Surgery, Saint Louis University, St. Louis, Missouri; 2Division Pediatric Goryeb Children’s Hospital, Morristown, New Jersey; 3Department Neurosurgery, University Tennessee Health Science Center, and 4Le Bonheur Memphis, Tennessee; 5De part ment Massachusetts General Hos pital, Boston, Massachusetts; 6Department Sur gery, Oregon & Portland, Oregon; 7De Hos pital Pittsburgh, Pennsylvania; 8Division Department Washington School Medicine, Mis souri; 9Department...
The CNS is regarded as an immunoprivileged organ, evading routine immune surveillance; however, the coordinated development of responses profoundly influences outcomes after brain injury. Innate lymphoid cells (ILCs) are cytokine-producing that critical for initiation, modulation, and resolution inflammation, but functional relevance mechanistic regulation ILCs unexplored acute We demonstrate increased proliferation all ILC subtypes within meninges up to 1 year experimental traumatic injury...
Matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry (MALDI-MSI) allows us to investigate the distribution of lipid molecules within tissues. We used MALDI-MSI identify prognostic gangliosides in tissue sections rat intracranial allografts glioma and mouse xenografts human medulloblastoma. In healthy adult rodent brain, GM1 GD1 were main types glycolipids. Both absent both transplants. The ganglioside GM3 was not present brain but highly expressed allografts....
Background: Increasing efforts have been made to reduce the incidence and severity of concussion in high-contact sports. Despite these efforts, a relative lack knowledge is available regarding modulating factors affecting injury. Purpose: To analyze potential influence game characteristics outcomes on professional football. Study Design: Descriptive epidemiology study. Methods: PBS Frontline Concussion Watch was used collect injury data from regular-season games 32 National Football League...
Abstract XB130 is an adaptor protein that functions as a mediator of multiple tyrosine kinases important for regulating cell proliferation, survival, migration and invasion. Formerly predicted oncogene, alterations its expression are documented in various human cancers. However, the exact role tumorigenesis unknown. To address function skin tumorigenesis, two-stage dimethylbenzanthracene (DMBA)/12-O-tetradecanoylphorbol 13-acetate (TPA) study was performed on knockout (KO), heterozygous (HZ)...
Introduction In the past few years, there has been a rising interest in both prevalence and short- long-term consequences of concussions. While main focus concussion-based research revolves around National Football League (NFL), attention is now shifting to other high contact leagues like Hockey (NHL), where constant player-to-player as well collisions with perimeter boards. body evidence surrounding injury concussion rates NHL substantially grown size over previous still void pertaining...
Background Sports-related concussion is a major cause of mild traumatic brain injury (mTBI). It possible that environmental factors, such as temperature, humidity, and stadium's altitude, may influence the overall incidence concussions during game. Purpose To examine impact barometric pressure, dew point, on incidence. Methods Public Broadcasting Service (PBS) FRONTLINE Concussion Watch was used to collect data 32 NFL teams regular season games from 2012 2015. Weather points were collected...
Thoracic spine fracture-dislocations due to motor vehicle accidents (MVAs) rarely involve double- level, noncontiguous lesions.A 19-year-old male following an MVA was paraplegic; he exhibited full motor/sensory loss below the T4 level (i.e., ASIA scale Grade A). The chest X-ray, magnetic resonance, and computed tomography studies confirmed T3-T5 T11-12 fractures, warranting T3-L3 thoracolumbar decompression fusion. Despite surgical intervention, patient's neurological status remained...
✓ The authors report on the management of occipital neuralgia secondary to an abnormality atlas in which posterior arch was separated by a fibrous band from lateral masses, resulting C-2 nerve root compression. causes and treatments as well development are reviewed.
Autofusion of spinal vertebrae is uncommon, but it can occur due to advanced degenerative processes and infection. Post-operative spontaneous fusion following non-fusion surgery (autofusion) also generally has been reported after laminoplasty, disc arthroplasty with without heterotopic ossification, histiocytosis biopsy. To the best our knowledge, post-operative autofusion in lumbar spine decompressive alone not previously. The authors present an occurrence a 29-year-old woman who underwent...
Neural progenitor cell (NPC) transplants are a promising therapy for treating spinal cord injury (SCI), however, their long-term role after engraftment and the relative contribution to ongoing functional recovery remains key knowledge gap. Selective human ablation techniques, currently being developed improve safety of transplant therapies in patients, may also be used as tools probe regenerative effects attributable individual grafted populations. The Herpes Simplex Virus Thymidine Kinase...
Introduction The increasing awareness and popularization of concussions in the research realm over last few years have begun to shed more light on detrimental effects associated with repetitive head trauma. While majority current literature focuses National Football League (NFL) Hockey (NHL), several other high-impact sports been implementing concussion management protocols protect their players. Australian (AFL) is a prime example major contact sport that has undertaken recent changes its...
Author-level metrics for assessing academic productivity have a significant impact on career advancement in academia. This study determined if 1-year growth rates author-level among New York (NY) metropolitan area neurosurgeons were associated with rank and/or years practice since graduating residency. H-index, document number, and citation number recorded monthly from March 2018 to 2019 eight NY training programs using the Scopus® abstract database. Subjects decrease any metric or an...
Amniotic band sequence (ABS) is a condition in which rupture of the amniotic sac leads to development broad spectrum fetal anomalies. A newborn male presented at term with multiple craniofacial and skeletal anomalies, including attachment placenta head, paramedian facial cleft, The patient has undergone several operations date. initial operation was performed remove attached off underlying dura, collagen matrix bound silicone membrane. subsequently underwent split-thickness skin grafting...
Flexion-extension magnetic resonance imaging (MRI) in the cervical spine is not universally used surgery. However, flexion-extension MRIs can identify previously undetected spinal stenosis, improve surgical decision-making, and maybe a better tool to evaluate postoperative outcomes. One uncommon complication after laminectomy, treat muscle weakness due subsequent dynamic cord compression by posterior paraspinal musculature. We present case of 41-year-old male who underwent decompression...