Fernando L. Sanchez

ORCID: 0000-0003-1996-4304
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Total Knee Arthroplasty Outcomes
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Injury Epidemiology and Prevention
  • Traffic and Road Safety
  • Neuroscience of respiration and sleep
  • Pharmaceutical studies and practices
  • Poisoning and overdose treatments
  • Healthcare Decision-Making and Restraints
  • Immune cells in cancer
  • Antimicrobial Resistance in Staphylococcus
  • Single-cell and spatial transcriptomics
  • Lower Extremity Biomechanics and Pathologies
  • Spinal Cord Injury Research
  • Histiocytic Disorders and Treatments
  • Sarcoma Diagnosis and Treatment
  • Musculoskeletal synovial abnormalities and treatments
  • Soft tissue tumor case studies
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Periodontal Regeneration and Treatments
  • Sleep and Work-Related Fatigue
  • Mesenchymal stem cell research
  • Vascular Malformations Diagnosis and Treatment
  • Neurofibromatosis and Schwannoma Cases
  • Soft tissue tumors and treatment

Tulane University
2020-2025

University of Nebraska Medical Center
2024

National Institute of Traumatology & Orthopaedic Rehabilitation
2023

Hospital Sírio-Libanês
2023

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2023

University of the Incarnate Word
2022

University of Almería
2014-2015

Hospital Universitario Virgen de las Nieves
1999

University of Alabama at Birmingham
1995

Abstract Bone is a multifaceted tissue requiring orchestrated interplays of diverse cells within specialized microenvironments. Although significant progress has been made in understanding cellular and molecular mechanisms component bone, revealing their spatial organization interactions native bone microenvironment crucial for advancing precision medicine, as they govern fundamental signaling pathways functional dependencies among various cells. In this study, we present the first...

10.1093/nar/gkae1298 article EN cc-by-nc Nucleic Acids Research 2025-01-11

Abstract Background Patients with a patient-reported penicillin allergy may be at greater risk for postoperative prosthetic joint infection (PJI) after total arthroplasty of the hip, knee, or shoulder. The increased PJI in these patients has been attributed to receiving less-effective perioperative antibiotic. However, prior reports did not fully address clinical characteristics unique patients, who inherently having PJI, which confound findings. Questions/purposes After controlling factors...

10.1097/corr.0000000000001497 article EN Clinical Orthopaedics and Related Research 2020-10-05

Abstract Background Arthrofibrosis remains one of the leading causes for revision in primary total knee arthroplasty (TKA). Similar nature to arthrofibrosis, hypertrophic scars and keloid formation are a result excessive collagen formation. There is paucity literature on whether there an association between development arthrofibrosis following TKA. Therefore, purpose this study was utilize large nationwide database identify compare rates postoperative complications related after TKA patients...

10.1186/s10195-020-00563-7 article EN cc-by Journal of Orthopaedics and Traumatology 2021-01-05

BACKGROUND: Air traffic controllers (ATC) work shifts and their schedules vary according to the characteristics of each airport. The human body adapts shiftwork differently. These adjustments affect health-disease process, predisposing ATC risk conditions associated with sleep deprivation lack night sleep, which can lead such as cardiovascular diseases, mood disorders, anxiety, obesity. This study investigated health, quality life exposed 8-h alternate 6-h rotational shifts. METHODS: was...

10.3357/amhp.4325.2015 article EN Aerospace Medicine and Human Performance 2015-09-21

Every year there are seven million new lawn mowers purchased in the United States, each of which is capable injuring young children, especially those > 14 years age. A total 33 children injured by a mower were reviewed to identify mechanism injury, determine factors responsible for accident, an effective treatment regime, and evaluate permanent impairment these patients. Classified according their as bystanders, 13 riders, six operators. Categorized anatomical location eight head eye...

10.1097/01241398-199501000-00018 article EN Journal of Pediatric Orthopaedics 1995-01-01

Drug-induced thrombocytopenia secondary to antibiotic exposure is a rare complication more commonly associated with other medications. In this review, we present case of antibiotic-induced and discuss the clinical picture approach identifying complication. With increasing use antibiotics that may be drug-induced in perioperative prophylaxis protocols, surgeons need cognizant cause postoperative patient. A delay recognition discontinuation offending agent can result significant complications...

10.1016/j.artd.2020.03.006 article EN cc-by-nc-nd Arthroplasty Today 2020-04-22

Iatrogenic intraoperative fractures are preventable complications in total knee arthroplasty. As press-fit fixation becomes more popular, further investigation into risk factors is needed. Some authors have suggested that smaller femurs may be at higher posterior-stabilized constructs owing to industry designs trending toward larger, constant box sizes increase the amount of bone resection relative stock.Finite element analysis (FEA) was used investigate effect insertion femoral components...

10.1016/j.artd.2020.03.014 article EN cc-by-nc-nd Arthroplasty Today 2020-05-11

Background and purpose - The increasing prevalence of total hip arthroplasty (THA) knee (TKA) within the growing elderly population is translating into a larger number patients with neuromuscular conditions such as myasthenia gravis (MG) receiving arthroplasty. We compared systemic joint complications following THA or TKA between MG without MG.Patients methods Patient records were queried from PearlDiver (Pearl Diver Inc, Fort Wayne, IN, USA), an administrative claims database, using...

10.1080/17453674.2020.1865031 article EN cc-by Acta Orthopaedica 2021-01-04

BackgroundTotal knee arthroplasty (TKA) is a successful treatment for patients with late stage osteoarthritis, yet arthrofibrosis remains consistent cause of TKA failure. Dupuytren's, Ledderhose and Peyronie's Diseases are related conditions increased fibroblast proliferation. The aim this study was to identify whether an association exists between these following TKA.MethodsPatient records were queried from 2010 2016 using administrative claims database compare the rates arthrofibrosis,...

10.1016/j.knee.2021.02.009 article EN cc-by-nc-nd The Knee 2021-02-25

Cryptococcus neoformans is a microscopic fungus that despite its pervasiveness in the environment rarely causes infection immunocompetent patients. In immunosuppressed patients, infections involving central nervous system (CNS) usually present as meningitis or meningoencephalitis. Cryptococcal are known to cause significant morbidity and mortality patients it difficult eradicate even with adequate antifungal treatment. A 44-year-old Hispanic male presented hospital headache, progressive...

10.1155/2022/2000246 article EN cc-by Case Reports in Infectious Diseases 2022-02-21

A 60-year-old Hispanic female was admitted with recurrent fevers, altered mental status, lymphadenopathy, hepatosplenomegaly, and pancytopenia. Initially, sepsis presumed because of urinary tract infection extended-spectrum beta-lactamase Escherichia coli. Despite appropriate therapy, her clinical condition continued to decline. An extensive workup obtained determine the source ailments. Bone marrow biopsy negative for leukemia, lymphoma, myelodysplastic syndrome; fluorescence in situ...

10.1016/j.ijid.2022.07.046 article EN cc-by-nc-nd International Journal of Infectious Diseases 2022-07-22

While osteoimmunology interactions between the immune and skeletal systems are known to play an important role in osteoblast development, differentiation bone metabolism related disease like osteoporosis, such either microenvironment or peripheral circulation vivo at single-cell resolution have not yet been characterized. We explored communications cells osteoblastic lineage (OBCs) by performing CellphoneDB CellChat analyses with RNA sequencing (scRNA-seq) data from human femoral head. also...

10.3389/fendo.2023.1107511 article EN cc-by Frontiers in Endocrinology 2023-03-27

<h2>Abstract</h2><h3>Background</h3> The impact of femoral nerve blocks (FNBs) during primary total knee arthroplasty (TKA) on clinical outcomes and pain management remains unclear. present research investigates the that continuous single-shot FNBs TKA have postoperative opioid claims short-term outcomes. <h3>Methods</h3> An administrative database was queried to identify patients who underwent with a FNB, or no FNB. More than 300,000 were analyzed from database. Rates compared via...

10.1016/j.artd.2020.10.001 article EN cc-by-nc-nd Arthroplasty Today 2020-11-21

Migrant families face challenges to health and well-being from COVID-19. We deployed Mobile Health for (mHealth-4-Mhealth) migrant families, a household-based program with mHealth-assisted at-home testing linkages community resources. assessed the reach, adoption, implementation of among rural enrolled in Title IC Nebraska Education Program February 2022 July 2023. describe successful adoption longitudinal use mHealth screening tools severe acute respiratory syndrome coronavirus 2 infection...

10.2105/ajph.2024.307746 article EN American Journal of Public Health 2024-08-22

Aseptic loosening of the acetabular component remains one leading causes early failure total hip arthroplasty. Poor apposition bone onto implant surface can be due to inaccurate reaming and osteonecrosis heat generated while reaming.New used reamers were tested on an MTS system using a clinically relevant force 87.6 N. A thermal profile depth achieved by analyzed compared between 2 cohorts. Heat required for community achieve same as new subsequently analyzed.The 3.4 mm deeper than (P <...

10.1016/j.artd.2020.12.002 article EN cc-by-nc-nd Arthroplasty Today 2021-01-14
Coming Soon ...