A5032155586- Surfactants and Colloidal Systems
- RNA Interference and Gene Delivery
- Virus-based gene therapy research
- Proteins in Food Systems
- Rheology and Fluid Dynamics Studies
- Polysaccharides Composition and Applications
- DNA and Nucleic Acid Chemistry
- Polymer Surface Interaction Studies
- CRISPR and Genetic Engineering
- Pickering emulsions and particle stabilization
- Drug Solubulity and Delivery Systems
- Hydrogels: synthesis, properties, applications
- Electrospun Nanofibers in Biomedical Applications
- Protein purification and stability
- CAR-T cell therapy research
Roche (Switzerland)
2023
FHNW University of Applied Sciences and Arts
2014-2017
Lund University
2012-2013
University of Coimbra
2010-2013
A procedure for the preparation of calcium alginate nanoparticles in aqueous phase water-in-oil (W/O) nanoemulsions was developed. The emulsions were produced from mixtures nonionic surfactant tetraethylene glycol monododecyl ether (C12E4), decane, and solutions up to 2 wt % sodium by means inversion temperature (PIT) emulsification method. This method allows finely dispersed without a large input mechanical energy. With concentrations 1–2 phase, showed good stability against Ostwald...
Calcium alginate beads, which are biodegradable and biocompatible, have been widely employed as delivery matrices for biomacromolecules. In the present work, feasibility of encapsulation DNA (which is used a model biomacromolecule) in calcium nanobeads (sub-200 nm size), prepared using recently developed protocol based on phase inversion temperature (PIT) emulsification method [Machado et al. Langmuir 2012, 28, 4131-4141], was assessed. The properties were compared to those corresponding...
In the present work, interactions between double-stranded (ds) or single-stranded (ss) DNA and nonionic ethylene oxide (EO) surfactants, with special attention to possible contributions from hydrophobic interactions, have been investigated using a multitechnique approach. It was found that presence of ss as well dsDNA induces slight decrease cloud point pentaethylene glycol monododecyl ether (C12E5). Assessment partitioning surfactant-rich surfactant-poor phases formed above showed polymer...