We report on a ternary isothermal system consisting of poly(ethylene oxide)/poly(propylene oxide) (PEO/PPO) amphiphilic block copolymer, “water”, and “oil” (where “water” are selective solvents for the different blocks), which exhibits richest structural polymorphism ever observed (in equilibrium) in mixtures containing amphiphiles (such as copolymers, surfactants, or lipids). The microstructure resulting from self-assembly PEO/PPO copolymer can vary normal (oil-in-water) micelles solution,...

The binary phase diagram of water–C12E5 has been studied with emphasis on the L3 and dilute lamellar phases, which were found to swell approximately 99.5 98.8 wt % water, respectively, much further than reported previously. Focusing these two we have carried out static light small-angle neutron scattering electrical conductivity measurements. repeat distance in was exceed 3000 Å. A small, but significant deviation from ideal one-dimensional swelling observed. This may be explained terms...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSelf-Assembly of Amphiphilic Block Copolymers: The (EO)13(PO)30(EO)13-Water-p-Xylene SystemPaschalis Alexandridis, Ulf Olsson, and Bjoern LindmanCite this: Macromolecules 1995, 28, 23, 7700–7710Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/ma00127a016https://doi.org/10.1021/ma00127a016research-articleACS PublicationsRequest reuse...

Amorphous drug nanosuspensions are prone to particle growth due Ostwald ripening. By incorporating a second component of extremely low aqueous solubility, ripening can be inhibited. These studies indicate that inhibit ripening, the drug/inhibitor mixture (in particles) must form single phase. The characterized by interaction parameter χ using Bragg-Williams theory, in which phase mixtures obtained for < 2. calculated from (crystalline) solubility inhibitor, provided inhibitor is liquid, and...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChange of the structure microemulsions with hydrophile-lipophile balance nonionic surfactant as revealed by NMR self-diffusion studiesUlf Olsson, Kozo Shinoda, and Bjoern LindmanCite this: J. Phys. Chem. 1986, 90, 17, 4083–4088Publication Date (Print):August 1, 1986Publication History Published online1 May 2002Published inissue 1 August 1986https://pubs.acs.org/doi/10.1021/j100408a050https://doi.org/10.1021/j100408a050research-articleACS...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsotropic bicontinuous solutions in surfactant-Solvent systems: the L3 phaseDavid Anderson, Haakan Wennerstroem, and Ulf OlssonCite this: J. Phys. Chem. 1989, 93, 10, 4243–4253Publication Date (Print):May 1, 1989Publication History Published online1 May 2002Published inissue 1 1989https://pubs.acs.org/doi/10.1021/j100347a067https://doi.org/10.1021/j100347a067research-articleACS PublicationsRequest reuse permissionsArticle...

A procedure for the preparation of calcium alginate nanoparticles in aqueous phase water-in-oil (W/O) nanoemulsions was developed. The emulsions were produced from mixtures nonionic surfactant tetraethylene glycol monododecyl ether (C12E4), decane, and solutions up to 2 wt % sodium by means inversion temperature (PIT) emulsification method. This method allows finely dispersed without a large input mechanical energy. With concentrations 1–2 phase, showed good stability against Ostwald...

We here develop stable bidimensional magnetic nanoclusters (2D-MNCs) of iron oxide nanocubes (IONCs) arranged in thin nanosheets closed-packed nanocubes. The assembly occurs by means a two-step approach: in...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSalt Effects on Nonionic Microemulsions Are Driven by Adsorption/Depletion at the Surfactant MonolayerAlexey Kabalnov, Ulf Olsson, and Hkan WennerstroemCite this: J. Phys. Chem. 1995, 99, 16, 6220–6230Publication Date (Print):April 1, 1995Publication History Published online1 May 2002Published inissue 1 April 1995https://doi.org/10.1021/j100016a068RIGHTS & PERMISSIONSArticle Views923Altmetric-Citations144LEARN ABOUT THESE METRICSArticle Views are...

Six lyotropic liquid crystalline and two solution (equilibrium) phases can be formed (at 25 °C) by an amphiphilic diblock copolymer composed of poly(ethylene oxide) poly(butylene in the presence water (selective solvent for PEO) "oil" (p-xylene, a selective PBO). Oil-in-water ("normal") micellar (L1), cubic crystals (I1), hexagonal (H1), lamellar structure (Lα) are with increase concentration along oil-lean side ternary phase diagram. A (L2), (I2), (H2), bicontinuous (V2), all water-in-oil...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCharacterization of micellar aggregates in viscoelastic surfactant solutions. A nuclear magnetic resonance and light scattering studyUlf Olsson, Olle Soederman, Paul GueringCite this: J. Phys. Chem. 1986, 90, 21, 5223–5232Publication Date (Print):October 1, 1986Publication History Published online1 May 2002Published inissue 1 October 1986https://pubs.acs.org/doi/10.1021/j100412a066https://doi.org/10.1021/j100412a066research-articleACS...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure, interactions, and diffusion in a ternary nonionic microemulsion near emulsification failureU. Olsson P. SchurtenbergerCite this: Langmuir 1993, 9, 12, 3389–3394Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/la00036a011https://doi.org/10.1021/la00036a011research-articleACS PublicationsRequest reuse permissionsArticle...

In the present paper, we have studied particle dissolution and crystal growth of poorly water soluble drug felodipine, using fluorescence as a probe for amount crystalline material. Dissolution kinetics is essentially diffusion-controlled, while rate significantly slower compared to diffusion-controlled limit. The deviation from diffusion control was characterized by effective length, λ, related surface integration process. Amorphous nanoparticles may be highly unstable in presence small...

The solvent-induced transition between self-assembled structures formed by the peptide AAKLVFF is studied via electron microscopy, light scattering, and spectroscopic techniques. based on a core fragment of amyloid beta-peptide, KLVFF, extended two alanine residues. exhibits distinct twisted fibrils in water or nanotubes methanol. For intermediate water/methanol compositions, these are disrupted replaced wide filamentous tapes that appear to be lateral aggregates thin protofilaments....

Aqueous dispersions of pure sodium and calcium smectite clays with platelet sizes on the order a few hundred nanometers were characterized using combination cryo-transmission electron microscopy (cryo-TEM) small-angle X-ray scattering (SAXS). With monovalent counterions clay is dispersed as individual platelets, seen by cryo-TEM, that into nematic phase. From SAXS one-dimensional swelling in water observed characteristic spacing hs = δ/ϕc, where separation between δ 1 nm effective thickness,...

The macro- and micro-features of bone can be assessed by using imaging methods. However, nano- molecular features require more detailed characterization, such as use e.g., vibrational spectroscopy X-ray scattering. Nano- also affect the mechanical competence tissue. aim present study was to reveal effects mineralization its alterations on mineral crystal scale, investigating spatial variation composition structure across cross-section femur diaphyses in young rats, healthy osteoporotic...

A rich phase behavior with lamellar, normal hexagonal, reverse and bicontinuous cubic liquid crystalline regions, as well water-rich (L1) oil-rich (L2) solutions, was observed at 25 °C in a ternary system composed of water, p-xylene, Pluronic 25R4, an amphiphilic block copolymer ethylene oxide (EO) propylene (PO) the structure (PO)19(EO)33(PO)19. The boundaries were identified using 2H-NMR inspection under polarized light. Small angle X-ray scattering employed to ascertain various phases...

The isothermal quasi-ternary-phase diagram of the lecithin−cyclohexane−water system was determined at 25 °C using a combination polarizing microscopy, small-angle X-ray diffraction, and NMR techniques. contains four lyotropic liquid-crystalline phases two isotropic liquid phases. Apart from lamellar (Lα) phase, there are only reverse-type aggregates with water interior, in addition to an essentially pure whose relative locations phase follow sequence (from oil corner surfactant corner):...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReversible Thermal Gelation in Polymer/Surfactant Systems. Control of the TemperatureK. Loyen, I. Iliopoulos, R. Audebert, and U. OlssonCite this: Langmuir 1995, 11, 4, 1053–1056Publication Date (Print):April 1, 1995Publication History Published online1 May 2002Published inissue 1 April 1995https://pubs.acs.org/doi/10.1021/la00004a002https://doi.org/10.1021/la00004a002research-articleACS PublicationsRequest reuse permissionsArticle...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAssociation and Thermal Gelation in Mixtures of Hydrophobically Modified Polyelectrolytes Nonionic SurfactantsAnne Sarrazin-Cartalas, Ilias Iliopoulos, Roland Audebert, Ulf OlssonCite this: Langmuir 1994, 10, 5, 1421–1426Publication Date (Print):May 1, 1994Publication History Published online1 May 2002Published inissue 1 1994https://pubs.acs.org/doi/10.1021/la00017a018https://doi.org/10.1021/la00017a018research-articleACS PublicationsRequest reuse...

A simple turbidimetric method was developed to measure the bulk concentration of drug in nanosuspensions. The concentrations measured were range from 1 μM mM. accuracy checked by determination crystalline nanosuspensions, i.e., solubility, which compared favorably solubilities a conventional method. Results obtained for amorphous nanosuspensions agreed with predictions using theory describing relative solubility between supercooled liquid and crystal. Further, it found that Ostwald ripening...