Isabela Sanches Pompeo da Silva

ORCID: 0000-0003-2000-2671
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Research Areas
  • Dental materials and restorations
  • Bone Tissue Engineering Materials
  • Advanced Drug Delivery Systems
  • Orthodontics and Dentofacial Orthopedics
  • Additive Manufacturing and 3D Printing Technologies
  • Electrospun Nanofibers in Biomedical Applications
  • Endodontics and Root Canal Treatments
  • Bone and Dental Protein Studies
  • Anatomy and Medical Technology
  • Periodontal Regeneration and Treatments
  • Tissue Engineering and Regenerative Medicine
  • Oral microbiology and periodontitis research
  • 3D Printing in Biomedical Research

Universidade de São Paulo
2019-2025

ABSTRACT In the present study, chitosan microspheres (MSCH) loaded with different concentrations of simvastatin (2%, 5%, and 10%) were synthesized as a biomaterial for dentin tissue engineering. The prepared by emulsion crosslinking method, was incorporated during process. then physicochemically morphologically characterized. Scanning electron microscopy infrared spectroscopy confirmed spherical morphology chemical incorporation into MSCH, respectively. UV–visible absorption controlled...

10.1002/jbm.b.35536 article EN Journal of Biomedical Materials Research Part B Applied Biomaterials 2025-01-29

Abstract This study analyzed the properties of three-dimensional (3D)-printed resins designed for interim restorations and subjected to different printing post-curing protocols. Specimens were manufactured with two 3D-printed at varying exposure times per layer, in accordance manufacturer’s recommendations (Tm) or using a calibrator (Tc). Subsequently, specimens post-cured 5, 10, 15 min. Trueness, surface roughness, color analyses performed. For biological characterization, incubated up 72 h...

10.1590/1807-3107bor-2025.vol39.019 article EN cc-by Brazilian Oral Research 2025-01-01

The development of biomaterials based on the combination biopolymers with bioactive compounds to develop delivery systems capable modulating dentin regeneration mediated by resident cells is goal current biology-based strategies for regenerative dentistry. In this article, potential a simvastatin (SV)–releasing chitosan-calcium-hydroxide (CH-Ca) scaffold was assessed. After incorporation SV into CH-Ca, characterization performed. Dental pulp (DPCs) were seeded onto scaffolds assessment...

10.1177/00220345211024207 article EN Journal of Dental Research 2021-07-27

The objective of this study was to create injectable photo-crosslinkable biomaterials, using gelatin methacryloyl (GelMA) hydrogel, combined with a decellularized bone matrix (BMdc) and deproteinized (BMdp) bovine matrix. These were intended serve as bioactive scaffolds for dentin regeneration. parameters GelMA hydrogel fabrication initially selected, followed by the incorporation BMdc BMdp at 1% (w/v) ratio. Nano-hydroxyapatite (nHA) also included control. A physicochemical characterization...

10.1002/jbm.a.37777 article EN Journal of Biomedical Materials Research Part A 2024-07-17
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