Marcia Avello

ORCID: 0000-0003-2004-5487
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Natural Antidiabetic Agents Studies
  • Antioxidant Activity and Oxidative Stress
  • Microbial Metabolites in Food Biotechnology
  • Essential Oils and Antimicrobial Activity
  • Natural Products and Biological Research
  • Phytochemistry and Biological Activities
  • Psidium guajava Extracts and Applications
  • Fungal Biology and Applications
  • Sphingolipid Metabolism and Signaling
  • Chromatography in Natural Products
  • Biochemical Analysis and Sensing Techniques
  • Free Radicals and Antioxidants
  • Lipid Membrane Structure and Behavior
  • Vitamin C and Antioxidants Research
  • Medicinal Plants and Neuroprotection
  • Phytochemical and Pharmacological Studies
  • Mesoporous Materials and Catalysis
  • GABA and Rice Research
  • Garlic and Onion Studies
  • Plant Toxicity and Pharmacological Properties
  • Bioactive Compounds and Antitumor Agents
  • Phytochemistry Medicinal Plant Applications
  • Fermentation and Sensory Analysis
  • Phytochemical compounds biological activities

University of Concepción
2008-2023

In this work, the anti‐ Helicobacter pylori effect of an aqueous extract from dried leaves Peumus boldus Mol. (Monimiaceae) was evaluated. This displayed high inhibitory activity against H . urease. Therefore, in order to clarify type substances responsible for such effect, a bioassay‐guided fractionation strategy carried out. The active compounds fractions were characterized through different chromatographic methods (RP‐HPLC; HILIC‐HPLC). fraction named F5 (mDP = 7.8) most urease with IC 50...

10.1002/ptr.5176 article EN Phytotherapy Research 2014-05-23

II Sem.2006 place constantly in the cells and they are necessary for human health, but process must be controlled with an adequate antioxidant protection.Among antioxidants that ingested diet, vitamins phenolic compounds prominent because neutralize radical species through several mechanisms.These can found plasma may stabilize reactive oxygen species, preventing reactions generate more deleterious molecules.Ingestion of diet is special importance, as well to avoid risk factors induce...

10.4067/s0718-04622006000200010 article EN cc-by-nc Atenea 2006-01-01

In the present work we carried out a comparative study of total phenolic contents and antioxidant capacity aqueous leaf extracts Ugni molinae Turcz., Myrtaceae (infusion Soxhlet extracted) prepared from continent Juan Fernández Island samples. The results revealed that phenol content (TPC), tannins (TTC) flavonoids (TFC) for U. extracts) island leaves were 38.5, 56.7 37.5% higher than those obtained with continent, respectively. Also, HPLC profiles showed important differences between...

10.1590/s0102-695x2012005000122 article EN cc-by-nc-nd Revista Brasileira de Farmacognosia 2012-10-10

Abstract Background Gunnera tinctoria has been collected by Mapuche-Pewenche people for food and medicinal purposes. The high polyphenol content of methanolic extract from G. leaves with chemical constituents such as ellagic acid quercetin derivatives suggests its application to prevent endothelial dysfunction oxidative stress. aim this study was provide evidence the protective effect on function reducing stress induced d -glucose H 2 O , well stimulating nitric oxide (NO) levels in human...

10.1186/s40659-020-00322-2 article EN cc-by Biological Research 2020-11-23

Maqui (Aristotelia chilensis) is an edible berry native to Southern Chile.The anthocyanin profiles and concentrations of this fruit have been widely studied.The high concentration anthocyanins confers a deep colour the skin pulp maqui berries, biological activity has attributed these compounds.However, other compounds such as flavonols hydroxycinnamic acid derivatives in not studied date.The objective was determine flavonol berries order expand knowledge base for fruit.Two extraction...

10.4067/s0717-97072016000100010 article EN Journal of the Chilean Chemical Society 2016-03-01

Avocado peels were used to extract proanthocyanidins (PACs) as starting material prepare semi-synthetic derivatives of epicatechin by nucleophilic attack with pyrogallol and resorcinol. One-step isolation both was successfully performed through centrifugal partition chromatography (CPC), identified TLC LC-MS/MS. The effect upon adherence Helicobacter pylori ATCC 43504 AGS cells the subsequent induction pro-inflammatory IL-8 release tested for these two derivatives. Bacterial synthesis...

10.4067/s0717-97072018000404222 article EN Journal of the Chilean Chemical Society 2018-12-01

Abstract In the present study, an RP high performance liquid chromatographic method was developed and validated for determination of allicin in garlic powder tablets. Chromatographic separation carried out on RP‐18 e column (125 mm×4 mm), using a mobile phase, consisting methanol–water (50:50 v/v), at flow rate 0.5 mL/min UV detection 220 nm. Ethylparaben used as internal standard. The assay linear concentrations 5.0–60.0 μg/mL. RSD precision <6.14%. accuracy above 89.11%. quantification...

10.1002/jssc.200700161 article EN Journal of Separation Science 2007-08-31

Pediculicide effect of a Eucaliptus globulus L formulationIntroduction: Pediculosis capitis is public health problem with high prevalence.The emergence parasite resistance to conventional pediculicide great concern worldwide.Objective: To develop alternatives pediculicide, effective and safe, based on the essential oil globulus.Method: Through bioassays active concentrations ranges were established, proceeded standardized, stable, pharmaceutical form, evaluating its effects our...

10.4067/s0716-10182016000400008 article EN Revista chilena de infectología 2016-08-01

Philesia magellanica (P.magellanica) is a plant collected in the Chilean Patagonia.Its antioxidant properties were assessed human erythrocytes exposed vitro to oxidative stress induced by HClO.Scanning electron microscopy (SEM) observations showed that HClO morphological alteration red blood cells from normal discoid spherocytic form, and of unequal size.However, concentration as low 1 mM gallic acid equivalents (GAE) P. aqueous extract neutralized change effects 50 µM HClO.On other hand, 20...

10.4067/s0717-97072015000200016 article EN Journal of the Chilean Chemical Society 2015-06-01
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