José Becerra

ORCID: 0000-0002-1444-1814
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About
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Research Areas
  • Fungal Biology and Applications
  • Chemical synthesis and alkaloids
  • Natural product bioactivities and synthesis
  • Biological Activity of Diterpenoids and Biflavonoids
  • Plant Pathogens and Fungal Diseases
  • Phytochemistry and Biological Activities
  • Essential Oils and Antimicrobial Activity
  • Sesquiterpenes and Asteraceae Studies
  • Mercury impact and mitigation studies
  • Plant biochemistry and biosynthesis
  • Allelopathy and phytotoxic interactions
  • Plant and animal studies
  • Forest Insect Ecology and Management
  • Mycorrhizal Fungi and Plant Interactions
  • Steroid Chemistry and Biochemistry
  • Cholinesterase and Neurodegenerative Diseases
  • Natural Compounds in Disease Treatment
  • Phytochemical compounds biological activities
  • Microbial Natural Products and Biosynthesis
  • Botanical Research and Chemistry
  • Insect-Plant Interactions and Control
  • Botany, Ecology, and Taxonomy Studies
  • Hymenoptera taxonomy and phylogeny
  • Marine Bivalve and Aquaculture Studies
  • Diatoms and Algae Research

University of Concepción
2015-2024

Instituto de Astrofísica de Canarias
2024

Universidad de La Laguna
2024

Asociación Colombiana de Facultades de Ingeniería
2024

Instituto Interamericano de Derechos Humanos
2023

Asociación por los Derechos Civiles
2023

National University of Trujillo
2021

Universidad de La Frontera
2020

Universidad Laica Eloy Alfaro de Manabí
2019

University of Alicante
2017

Abstract Five lignans (secoisolariciresinol, pinoresinol, eudesmin, lariciresinol, and lariciresinol-4- methyl ether) were isolated from an MeOH extract Araucaria araucana (Mol.) K. Koch wood for the first time in this species their structures determined with spectroscopic methods. The antimicrobial activities of these compounds bacteria Citrobacter sp., Bacillus subtilis, Escherichia coli, Micrococcus luteus, Staphylococcus aureus, Pseudomonas aeruginosa, white rooting staining fungi Mucor...

10.1515/znc-2006-1-207 article EN cc-by-nc-nd Zeitschrift für Naturforschung C 2006-02-01

The antifungal activity of molecular identified Chilean saprobiontic fungi, Trichoderma viride, Schizophyllum commune and Trametes versicolor, on the fungal plant pathogens Botrytis cinerea Fusarium oxysporum, saprotrophic mould Mucor miehei was investigated using two types inhibition bioassay: (1) bi-compartmented Petri dishes (2) Erlenmeyer flasks connected by their upper parts. chemical composition volatile organic compounds (VOCs) released fungi also headspace solid-phase microextraction...

10.1080/02757540.2011.596832 article EN Chemistry and Ecology 2011-08-17

Ten sesquiterpenes (a-cubebene, copaene, a-caryophyllene, caryophyllene-4,5-epoxide, d-cadinene, cubenol, epicubenol, torreyol, humulene-1,2-epoxide, 15-copaenol) and six diterpenes (hinokione, hinokiol, ferruginol, 6,7-dehydroferruginol, totarol, sugiol) were isolated identified from Pilgerodendron uviferum (D. Don) Florin wood bark. The molecular structures elucidated by spectroscopic methods. Twelve pure compounds tested for antimicrobial activity against standard bacterial...

10.4067/s0717-97072004000200010 article EN Journal of the Chilean Chemical Society 2004-06-01

Abstract The potential neuroprotective properties of fruits have been widely recognized. In this study, we evaluated the protective a blueberry extract (BB‐4), rich in polyphenols, neurodegenerative model induced by amyloid‐β peptide (Aβ). Chronic treatment with Aβ drastically reduced synaptic transmission and extent secretory vesicles, which were recovered partially BB‐4. Also, Ca 2+ transients hippocampal neurons preincubated (0.5 5 μM) about 25% ± 3% 30% 2, respectively. work, demonstrate...

10.1002/jnr.22679 article EN Journal of Neuroscience Research 2011-06-06

The invasion process of Acacia dealbata is partially mediated by releasing allelochemicals that affect native plants and soil microbes. However, non-volatile chemical compounds responsible for the allelopathic effect remain unknown, even though potential this species has been studied under Europe conditions. We examined aqueous extracts obtained from different plant materials A. dealbata: litter leaf, flowers, pods seeds fresh leaves also extract's phytotoxicity evolution on germination...

10.1080/02757540.2015.1050004 article EN Chemistry and Ecology 2015-07-03

Plant species that growth close to or under the canopy of Acacia dealbata Link (Fabaceae, subfamily: Mimosoideae) within its non-native range, survive with difficulty not at all, especially if they are native.This phenomenon has been attributed allelopathy; one strategies used by A. trigger an invasion process.Native Quillaja saponaria Molina (tree) and Helenium aromaticum (Hook.)H.L. Bailey (herb), share dealbata's range in South-central Chile.This study was performed on Mediterranean...

10.4067/s0717-66432015000200007 article EN Gayana. Botánica 2015-12-01

The Chilean Sepedonium aff. chalcipori strain KSH 883, isolated from the endemic Boletus loyo Philippi, was studied in a polythetic approach based on chemical, molecular, and biological data. A taxonomic study of using molecular data ITS, EF1-α, RPB2 barcoding genes confirmed position within S. clade, but also suggested separation this clade into three different species. Two new linear 15-residue peptaibols, named chilenopeptins (1) B (2), together with known peptaibols tylopeptins (3) (4)...

10.1021/acs.jnatprod.5b01018 article EN Journal of Natural Products 2016-03-08

Acetylcholinesterase is an important target for control of neurodegenerative diseases causing cholinergic signaling deficit. Traditionally, galanthamine has been used as Amaryllidaceae-derived acetylcholinesterase inhibitor, although new Amaryllidaceae plants could serve source better inhibitors. Therefore, the objective this study was to characterize alkaloid composition from bulbs Rhodolirium andicola (Poepp.) Traub, a native Chilean specie, and assess their inhibitory activity on by in...

10.1016/j.bjp.2017.11.009 article EN cc-by-nc-nd Revista Brasileira de Farmacognosia 2018-01-01

Essential oils obtained from Gomortega keule, Laurelia sempervirens, Origanum vulgare, Eucalyptus globulus, and Thymus vulgaris were analyzed by gas chromatography chromatography-mass spectrometry evaluated for their toxicity against adults of Sitophilus zeamais (Motschulky) Acanthoscelides obtectus (Say) (Coleoptera).Contact was assayed impregnating filter paper discs with the oils.The amount essential applied in each desiccator (4 l capacity) 4, 8, 16, or 32 µl, corresponding to 1, 2, 8...

10.4067/s0717-97072008000100026 article EN Journal of the Chilean Chemical Society 2008-03-01

Components of essential oils from the Chilean Monimiaceae, boldo (Peumus boldus Mol.), tepa (Laureliopsis philippiana (Looser) Schodde), and laurel (Laurelia sempervirens (Ruiz & Pav.) Tul.) were determined using Gas Chromatography-Mass Spectrometry (GCMS) fungistatic activity was tested against Rhizoctonia solani Kühn (Donk), Pythium irregulare Buisman, Ceratocystis pilifera (Fr.) C. Moreau, Phragmidium violaceum (Schultz) G. Winter, Fusarium oxysporum Schltdl.The Monimiaceae species shared...

10.4067/s0718-58392009000100004 article EN Chilean journal of agricultural research 2009-03-01

Alzheimer's disease (AD) is characterized by the presence of different types extracellular and neurotoxic aggregates amyloid-β (Aβ). Recently, bioactive compounds extracted from natural sources showing neuroprotective properties have become

10.3233/jad-2012-120229 article EN Journal of Alzheimer s Disease 2012-09-11

From the fruiting body of ectomycorrhizal fungi Cortinarius xiphidipus, sterols were identified from crude extract and cytotoxic effect ergosta-4, 6, 8(14), 22-tetraen-3-one (ergone) was evaluated. Ten including ergosta-3,5,7,9(11),22-pentaene, (22E)-ergosta-5,7,9(11),22-tetraen-3b-ol, (3β,22E)-ergosta-5,7,22-trien-3-ol, (22E)-ergosta-7,22-dien-3-ol, neoergosterol, (3β)-ergosta-5,8-dien-3-ol, (3β)-ergosta-7-en-3-ol, stigmasterol, stigmasterol 22,23-dihydro...

10.1080/14786419.2016.1185717 article EN Natural Product Research 2016-05-19

From the aerial parts of Maytenus disticha, we have isolated 9β-benzoyloxy-1α,2α,6β,8α,15- penta-acetoxy-dihydro-β-agarofuran (1) and from seeds boaria 9β-furoyloxy-1α, 6β, 8α-triacetoxy-dihydro-β-agarofuran (2). These compounds their MeOH hexane/ethyl acetate (1:1 v/v) extracts were evaluated for effects on fall armyworm (Spodoptera frugiperda). Toosendanin, a commercial insecticide derived Melia azedarach was used as positive control. When tested activity using neonate larvae in nochoice...

10.1515/znc-2001-7-821 article EN Zeitschrift für Naturforschung C 2001-08-01

In the present work we carried out a comparative study of total phenolic contents and antioxidant capacity aqueous leaf extracts Ugni molinae Turcz., Myrtaceae (infusion Soxhlet extracted) prepared from continent Juan Fernández Island samples. The results revealed that phenol content (TPC), tannins (TTC) flavonoids (TFC) for U. extracts) island leaves were 38.5, 56.7 37.5% higher than those obtained with continent, respectively. Also, HPLC profiles showed important differences between...

10.1590/s0102-695x2012005000122 article EN cc-by-nc-nd Revista Brasileira de Farmacognosia 2012-10-10

Due to the increasing emergence of resistance bacterial pathogens current antibiotics, we have examined marine fungi present in sea sediments obtained 200 m offshore discover new antibacterial compounds active against multidrug-resistant bacteria. One strain, identified as Emericellopsis minima, was isolated from Talcahuano Bay (Chile). From liquid culture E. Emerimicin IV, a unique fungal peptaibol that exhibited activity. The structure this compound assigned by interpretation 1H NMR and...

10.1080/14786419.2017.1344655 article EN Natural Product Research 2017-07-03
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