A5001805249- Cancer-related molecular mechanisms research
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Pharmacological Effects of Natural Compounds
- Immune cells in cancer
- Circular RNAs in diseases
- Phytochemicals and Medicinal Plants
- MicroRNA in disease regulation
- Infective Endocarditis Diagnosis and Management
- Ginseng Biological Effects and Applications
Qingdao University
2021-2023
Yuhuangding Hospital
2021-2023
Beijing Anzhen Hospital
2022
Capital Medical University
2022
Myocardial hypoxia is an important factor causing myocardial infarction (MI). Interestingly, many unknown factors in the molecular mechanism of MI remain unclear. Our study explored role lncRNA growth arrest-specific 5 (GAS5) cell injury under hypoxia.
Hesperetin (HES), whose main pharmacological effects are anti-inflammatory and cardioprotective properties. In our study, we investigated the role of HES in lipopolysaccharide (LPS)-induced inflammation apoptosis H9c2 cells.
In the present study, mitral valve tissues from three stenosis patients with RHD by replacement and two healthy donors were harvested conducted DNA methylation signature on PRKCA MeDIP-qPCR. The presence of hypomethylated CpG islands at promoter 5ʹ terminal was observed in accompanied highly expressed down-regulated antisense long non-coding RNA (lncRNA) PRKCA-AS1 compared to health control. Furthermore, enrichments DNMT1/3A/3B detected ChIP-qPCR assay vivo human cardiomyocyte AC16 RL-14...
Abstract Objective: Current studies have suggested that fetal congenital heart diseases (CHDs) are caused by various factors. However, few data is available with respect to the aspect in China. This study aimed detect associated maternal and factors of CHD a large sample Study Design: Pregnant women who underwent echocardiography (N=5024) were recruited our hospital between May 2018 September 2019. Of these, 875 pregnant had fetuses CHD. The sociodemographic lifestyle characteristics some...
Abstract Objective Current studies have suggested that fetal congenital heart diseases (CHDs) are caused by various factors. However, few data is available with respect to the aspect in China. This study aimed detect associated maternal and factors of CHD a large sample Study Design: Pregnant women who underwent echocardiography (N = 5024) were recruited our hospital between May 2018 September 2019. Of these, 875 pregnant had fetuses CHD. The sociodemographic lifestyle characteristics some...