A5021095366- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Visual perception and processing mechanisms
- EEG and Brain-Computer Interfaces
- Memory and Neural Mechanisms
- Photoreceptor and optogenetics research
- Visual Attention and Saliency Detection
- Neuroscience, Education and Cognitive Function
- Cognitive and developmental aspects of mathematical skills
- Glioma Diagnosis and Treatment
- Epilepsy research and treatment
- Behavioral Health and Interventions
- Motor Control and Adaptation
- Global Health Workforce Issues
- Diversity and Career in Medicine
- Mind wandering and attention
- Morphological variations and asymmetry
- Neurobiology of Language and Bilingualism
- Mathematics Education and Teaching Techniques
- Neural and Behavioral Psychology Studies
- COVID-19 and healthcare impacts
- Muscle activation and electromyography studies
- Neuroscience and Music Perception
- Traumatic Brain Injury and Neurovascular Disturbances
- Neural Networks and Applications
University of Toronto
2023-2024
University Health Network
2023-2024
Krembil Research Institute
2023-2024
Toronto Western Hospital
2023
Hertie Institute for Clinical Brain Research
2021-2022
Senckenberg Centre for Human Evolution and Palaeoenvironment
2021
University of Iowa Hospitals and Clinics
2020
University of Iowa
2020
University of Tübingen
2016-2019
Bernstein Center for Computational Neuroscience Tübingen
2017
Humans have the remarkable cognitive capacity to rapidly adapt changing environments. Central this is ability form high-level, abstract representations that take advantage of regularities in world support generalization1. However, little known about how these are encoded populations neurons, they emerge through learning and relate behaviour2,3. Here we characterized representational geometry neurons (single units) recorded hippocampus, amygdala, medial frontal cortex ventral temporal...
Despite strong evidence to the contrary in literature, microsaccades are overwhelmingly described as involuntary eye movements. Here we show both human subjects and monkeys that individual of any direction can easily be triggered: (1) on demand, based an arbitrary instruction, (2) without special training, (3) visual guidance by a stimulus, (4) spatially temporally accurate manner. Subjects voluntarily generated instructed "memory-guided" readily, similarly how they made normal...
Abstract Humans have the remarkable cognitive capacity to rapidly adapt changing environments. Central this is ability form high-level, abstract representations that take advantage of regularities in world support generalization 1 . However, little known about how these are encoded populations neurons, they emerge through learning, and relate behavior 2,3 Here we characterized representational geometry neurons (single-units) recorded hippocampus, amygdala, medial frontal cortex, ventral...
The foveal visual image region provides the human system with highest acuity. However, it is unclear whether such a high fidelity representational advantage maintained when locations are committed to short-term memory. Here, we describe paradoxically large distortion in target location recall by humans. We briefly presented small, but contrast, points of light at eccentricities ranging from 0.1 12°, while subjects their line sight on stable target. After brief memory period, indicated...
Abstract Physical exercise acutely improves hippocampal-based learning and memory in rodents humans. While animal studies have mainly offered cellular- synaptic-level accounts of these effects, human neuroimaging show that hippocampal-cortical connectivity at the macroscale level. However, neurophysiological basis for exercise-induced effects on circuits remains unknown. A growing body evidence supports critical role hippocampal sharp wave-ripples (SWRs) memory. Moreover, recent suggest...
Abstract Microsaccades are overwhelmingly described as involuntary eye movements. Here we show in both human subjects and monkeys that individual microsaccades of any direction can easily be triggered: (1) “on demand”, based on an arbitrary instruction, (2) without special training, (3) visual guidance by a stimulus, (4) spatially temporally accurate manner. Subjects voluntarily generated instructed “memory-guided” readily, similarly to how they made normal visually-guided ones. In two...
Microsaccades are commonly described as "involuntary". However, under a variety of task conditions, microsaccade directions, amplitudes, and frequencies can be systematically modulated. While these results hint at voluntary control, they primarily derived from likelihood measures rather than "at will" triggering individual movements. Here we asked whether movements in the amplitude range triggered: (1) "on demand" based on an arbitrary instruction, (2) without special training, (3) visual...
ABSTRACT Objective Electrical cortical stimulation (ECS) has been the gold standard for intraoperative functional mapping in neurosurgery, yet it carries risk of induced seizures. Here we assess safety focal cooling (CC) as a potential alternative to ECS brain mapping. Methods We retrospectively reviewed 40 consecutive subjects (n=13 tumor, 27 mesial temporal lobe epilepsy (MTLE) resection) who underwent CC during craniotomy at University Iowa Hospital and Clinics from 2007 through 2019 (CC...
Abstract Speech motor control requires integration of sensory and information. Bidirectional communication between frontal auditory cortices is crucial for speech production, self-monitoring control. We used cortical direct electrical stimulation (DES) to functionally dissect audio-motor interactions underlying production Eleven neurosurgical patients performed a visually cued vocal task in which short feedback perturbation was introduced during vocalization. evaluated the effect DES on...
Recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic represents an important negative impact on global training of neurosurgery residents. Even before the pandemic, discrimination is a challenge that neurosurgical residents have consistently faced. In present study, we evaluated discriminatory conditions experienced by during their in Mexico SARS-CoV-2 pandemic.An electronic survey 18 questions was sent among registered Mexican Society Neurological Surgery (MSNS),...
Abstract The foveal visual image region provides the human system with highest acuity. However, it is unclear whether such a high fidelity representational advantage maintained when locations are committed to short term memory. Here we describe paradoxically large distortion in target location recall by humans. We briefly presented small, but contrast, points of light at eccentricities ranging from 0.1 12 deg, while subjects their line sight on stable target. After brief memory period,...