Guanbin Zhang

ORCID: 0000-0003-2037-343X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Advanced Fiber Optic Sensors
  • Photonic and Optical Devices
  • Semiconductor Lasers and Optical Devices
  • Hepatitis B Virus Studies
  • HIV, Drug Use, Sexual Risk
  • Biosensors and Analytical Detection
  • HIV/AIDS Research and Interventions
  • Hepatitis C virus research
  • Advanced Photonic Communication Systems
  • Advanced biosensing and bioanalysis techniques
  • Bacteriophages and microbial interactions
  • Hearing, Cochlea, Tinnitus, Genetics
  • Analytical Chemistry and Sensors
  • Optical Network Technologies
  • HIV Research and Treatment
  • Immune cells in cancer
  • SARS-CoV-2 detection and testing
  • Gene expression and cancer classification
  • Advanced Computational Techniques and Applications
  • Connexins and lens biology
  • Photonic Crystal and Fiber Optics
  • Microfluidic and Capillary Electrophoresis Applications
  • Cancer Immunotherapy and Biomarkers
  • Viral gastroenteritis research and epidemiology
  • Gas Sensing Nanomaterials and Sensors

Fujian Medical University
2023-2024

Mianyang Third People's Hospital
2022-2024

Chengdu Medical College
2024

Sichuan Mianyang 404 Hospital
2021-2022

South China Normal University
2010-2021

Tsinghua University
2007-2018

Beijing Biocytogen (China)
2007

ObjectiveThe aim of this study is to comprehensively investigate the prevalence and distribution patterns three common genetic variants associated with hearing loss (HL) in Chinese neonatal population. Methods: Prior June 30, 2023, an extensive search screening process was conducted across multiple literature databases. R software utilized for conducting meta-analyses, cartography, correlation analyses. Results: Firstly, our identified a total 99 studies meeting inclusion criteria. Notably,...

10.1016/j.heliyon.2024.e24850 article EN cc-by-nc-nd Heliyon 2024-01-28

A single core-offset Mach-Zehnder interferometer (MZI) coated with polyvinyl alcohol (PVA) for simultaneous measurement of relative humidity (RH) and temperature is proposed in this paper. The sensing structure fabricated by splicing dispersion compensating fiber (DCF) no-core (NCF) two single-mode fibers (SMF) at both ends, where the located SMF DCF. part cladding DCF etched to excite high-order mode (LP 10 ), PVA on area. refractive index varies due adsorption water molecules. Therefore,...

10.1364/oe.430367 article EN cc-by Optics Express 2021-07-03

Background Hepatitis B poses a significant global public health challenge, with mother-to-child transmission (MTCT) being the primary method of hepatitis virus (HBV) transmission. The prevalence HBV infection in China is highest Asia, and it carries greatest burden globally. Objective This study aims to critically evaluate existing local strategies for preventing MTCT proposed potential enhancements by analyzing among pregnant women their neonates Yinchuan. Methods From January 2017 December...

10.2196/60021 article EN cc-by JMIR Public Health and Surveillance 2024-09-04

We have manufactured an intensity modulated optical fiber SMDMS sensor with hydroxyethyl cellulose (HEC) hydrogel coating for simultaneous measurement of RH and temperature. The was by splicing single-mode (SMF), multi-mode (MMF), dispersion compensation (DCF), MMF, SMF in sequence to form a structure + MMF DCF (SMDMS). cladding MMFs were corroded hydrofluoric acid (HF) coated HEC excite strong evanescent field increase the sensitivity sensor. adsorption water molecules will cause change...

10.1364/oe.442377 article EN cc-by Optics Express 2021-12-23

A simple fiber-optic displacement sensor based on reflective intensity modulated technology is demonstrated using a fiber collimator. The sensing range over 30 cm, which 100 times that of the conventional normal single-mode fiber. measured data are fitted into linear equation very well and values R-square more than 0.995. sensitivity device achieves 0.426 dB/cm 5–30 cm. By applying relative technique, errors resulted from fluctuation light source influences environment effectively...

10.1063/1.3518971 article EN Review of Scientific Instruments 2010-12-01

Research has shown that hepatitis B virus (HBV) genotypes are closely linked to the clinical manifestations, treatment, and prognosis of disease. To study association between genotype drug-resistant HBV mutations in 620 Chinese patients with chronic infection. DNA levels were determined using real-time quantitative PCR plasma samples. Microarrays performed for simultaneous detection (HBV/B, C, D) drug-resistance-related hotspot mutations. A portion samples analyzed microarrays was selected...

10.1016/j.bjid.2015.03.012 article EN cc-by-nc-nd The Brazilian Journal of Infectious Diseases 2015-05-01

Background Since the introduction of HIV self-testing by UNAIDS in 2014, practice has been extensively implemented around world. (HIVST) was developed China 2015, and online purchase HIVST kits through e-commerce platforms since become most important delivery method for self-testing, with advantages such as user-friendliness, speed, better privacy protection. Objective Understanding spatiotemporal characteristics kit purchasing behavior identifying potential impacting factors will help...

10.2196/37922 article EN cc-by JMIR Public Health and Surveillance 2022-08-03

Abstract Cancer cells evolve various mechanisms to overcome cellular stresses and maintain progression. Protein kinase R (PKR) its protein activator (PACT) are the initial responders in monitoring diverse stress signals lead inhibition of cell proliferation apoptosis consequence. However, regulation PACT-PKR pathway cancer remains largely unknown. Herein, we identify that long non-coding RNA (lncRNA) aspartyl-tRNA synthetase antisense 1 ( DARS-AS1 ) is directly involved promotes cells. Using...

10.1038/s42003-022-03778-y article EN cc-by Communications Biology 2022-08-15

The clamshell isothermal nucleic acid amplification analyzer RTisochip-S, a next-generation instrument featuring improved structural design, enhanced functional integration, reduced cost, and increased portability, was assessed for its suitability in clinical respiratory pathogens detection.

10.1016/j.plabm.2024.e00394 article EN cc-by-nc-nd Practical Laboratory Medicine 2024-04-16

<sec> <title>BACKGROUND</title> Hepatitis B poses a significant global public health challenge, with mother-to-child transmission (MTCT) being the primary method of hepatitis virus (HBV) transmission. The prevalence HBV infection in China is highest Asia, and it carries greatest burden globally. </sec> <title>OBJECTIVE</title> This study aims to critically evaluate existing local strategies for preventing MTCT proposed potential enhancements by analyzing among pregnant women their neonates...

10.2196/preprints.60021 preprint EN 2024-04-29

Abstract Infiltration of myeloid-derived suppressor cells (MDSCs) leads to Immunosuppressive tumor microenvironment (TME), which is one the major causes for low objective response rates immune checkpoint blockade (ICB) therapy. Here, we report that chemical inhibition p38α reverses this MDSC-induced immunosuppressive TME and improves immunotherapy efficacy in triple negative breast cancer (TNBC). Firstly, by combining immunological phenotype (TIP) gene signature high throughput sequencing...

10.1101/2023.03.31.535102 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-04-03

The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2) has swept the world and poses a serious threat to human health. In post-pandemic-era, we must remain vigilant against co-infection of SARS-CoV-2 other viruses. More accurate convenient detection methods are required for diagnosis due its prolonged existence. this study, application value novel lyophilized-pellet-based 2019-nCoV nucleic acid diagnostic kit (PCoV-Kit) was evaluated comparing it...

10.1371/journal.pone.0292902 article EN cc-by PLoS ONE 2023-10-25

Numerous epidemic outbreaks related to cold chains have occurred since the coronavirus disease 2019 (COVID-19) outbreak, suggesting potential danger of severe acute respiratory syndrome 2 (SARS-CoV-2) transmission through chain foods (CCFs). By analyzing SARS-CoV-2 RNA contamination CCFs imported from Fuzhou ports, this study evaluated and via maritime chains, with aim provide suggestions for supervision public health management. The statistical analysis included 131,385 samples. majority...

10.1016/j.heliyon.2023.e21954 article EN cc-by-nc-nd Heliyon 2023-11-01

A relative humidity (RH) sensor based on a seven-core fiber (SCF) coated with graphene oxide (GO) is proposed. The sensing structure consists of part the SCF sandwiched between two parts no-core fibers (NCFs). was corroded by hydrofluoric acid until six outer cores were exposed to air and then layer GO. NCFs play splitting coupling roles because core diameter mismatch. center acts as reference arm, act arm construct Mach–Zehnder interferometer. When GO absorbs water molecules, its refractive...

10.1117/1.oe.60.11.117105 article EN Optical Engineering 2021-11-19

Abstract The lasing wavelength shift characteristics of amplified spontaneous emission (ASE)‐injected wavelength‐locked Fabry‐Perot laser‐diodes used in the division multiplexed passive optical network are studied. at different injected‐ASE powers and bias currents experimentally evaluated. saturation effect has been found as current increases. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett, 2011; View this article online wileyonlinelibrary.com. DOI 10.1002/mop.26088

10.1002/mop.26088 article EN Microwave and Optical Technology Letters 2011-04-22
Coming Soon ...