Alan Roger Santos‐Silva

ORCID: 0000-0003-2040-6617
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About
Contact & Profiles
Research Areas
  • Head and Neck Cancer Studies
  • Oral and Maxillofacial Pathology
  • Oral Health Pathology and Treatment
  • Oral health in cancer treatment
  • Salivary Gland Tumors Diagnosis and Treatment
  • Cancer Diagnosis and Treatment
  • Tumors and Oncological Cases
  • Laser Applications in Dentistry and Medicine
  • Bone Tumor Diagnosis and Treatments
  • Oral and gingival health research
  • Ear and Head Tumors
  • Salivary Gland Disorders and Functions
  • Dental Implant Techniques and Outcomes
  • Bone health and treatments
  • Sarcoma Diagnosis and Treatment
  • Head and Neck Surgical Oncology
  • Viral-associated cancers and disorders
  • AI in cancer detection
  • Cancer and Skin Lesions
  • Dental Radiography and Imaging
  • Dermatological and COVID-19 studies
  • Oral and Craniofacial Lesions
  • Dental Research and COVID-19
  • Patient-Provider Communication in Healthcare
  • Soft tissue tumor case studies

Universidade Estadual de Campinas (UNICAMP)
2016-2025

Methodist University of Piracicaba
2016-2025

Informatics Institute of Technology
2025

Forest Science and Research Institute
2017-2024

RELX Group (United States)
2023-2024

Universidade Federal de Minas Gerais
2023

Universidad de Los Andes, Chile
2023

Fundação Faculdade de Odontologia
2014-2023

University of Talca
2022

Catholic University of the Maule
2022

Some oral manifestations have been observed in patients with coronavirus disease 2019 (COVID-19). However, there is still a question about whether these lesions are due to infection or secondary resulting from the patient's systemic condition. Thus, this article aims report an additional case of condition patient diagnosed COVID-19. Our patient, sixty-seven-year-old Caucasian man, tested positive and presented such as recurrent herpes simplex, candidiasis, geographic tongue. We support...

10.1016/j.ijid.2020.06.012 article EN cc-by-nc-nd International Journal of Infectious Diseases 2020-06-09

Abstract Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological and molecular characteristics limiting the standard tumor−node−metastasis prognosis classification. Therefore, defining biological signatures that allow assessing prognostic outcomes for OSCC patients would be great clinical significance. Using histopathology-guided discovery proteomics, we analyze neoplastic islands stroma from invasive tumor front (ITF) inner to identify differentially...

10.1038/s41467-018-05696-2 article EN cc-by Nature Communications 2018-08-30

Abstract Background Salivary gland tumours (SGT) are a relatively rare group of neoplasms with wide range histopathological appearance and clinical features. To date, most the epidemiological studies on salivary limited for variety reason including being out extrapolated from either single centre or country studies, investigating major minor glands only. Methods This study aimed to mitigate these shortcomings by analysing data demographic, anatomical location histological diagnoses SGT...

10.1007/s12105-022-01459-0 article EN cc-by Head and Neck Pathology 2022-05-27

Abstract The development and progression of oral cavity squamous cell carcinoma (OSCC) involves complex cellular mechanisms that contribute to the low five-year survival rate approximately 20% among diagnosed patients. However, biological processes essential tumor are not completely understood. Therefore, detecting alterations in salivary proteome may assist elucidating modulated OSCC improve clinical prognosis disease. whole saliva extracellular vesicles (EVs) from patients with healthy...

10.1038/srep16305 article EN cc-by Scientific Reports 2015-11-05

Oral cancer/oral squamous cell carcinoma is among the top ten most common cancers globally, with over 500,000 new cases and 350,000 associated deaths every year worldwide. There a critical need for objective, novel technologies that facilitate early, accurate diagnosis. For this purpose, we have developed method to classify images as “suspicious” “normal” by performing transfer learning on Inception-ResNet-V2 generated automated heat maps highlight region of likely be involved in decision...

10.3390/cancers13061291 article EN Cancers 2021-03-14

Radiation-related caries is a unique form of rampant decay and complication head neck radiotherapy that frequently causes generalized dental destruction impairs quality life in cancer patients. The aim this study was to investigate the patterns demineralization irradiated patients establish whether direct radiogenic damage dentition might be important progression radiation-related caries. Teeth from who had concluded were examined histologically by polarized light microscopy, ultrastructure...

10.1159/000192799 article EN Caries Research 2009-01-01
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