A5108166940- Head and Neck Cancer Studies
- Oral health in cancer treatment
- Cancer Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Oral Health Pathology and Treatment
- Laser Applications in Dentistry and Medicine
- Salivary Gland Tumors Diagnosis and Treatment
- Dental Implant Techniques and Outcomes
- Bone Tumor Diagnosis and Treatments
- Soft tissue tumor case studies
- Ear and Head Tumors
- Salivary Gland Disorders and Functions
- Peptidase Inhibition and Analysis
- Patient-Provider Communication in Healthcare
- Head and Neck Surgical Oncology
- Viral-associated cancers and disorders
- Tumors and Oncological Cases
- Dental Radiography and Imaging
- Oral microbiology and periodontitis research
- Oral and gingival health research
- Reconstructive Facial Surgery Techniques
- Advanced Proteomics Techniques and Applications
- Sarcoma Diagnosis and Treatment
- HIV/AIDS oral health manifestations
- Reconstructive Surgery and Microvascular Techniques
Instituto do Câncer do Estado de São Paulo
2016-2025
Universidade de São Paulo
2016-2025
Universidade Estadual de Campinas (UNICAMP)
2014-2024
Hospital Sírio-Libanês
2020-2024
Hospital São Paulo
2024
Methodist University of Piracicaba
2024
Centro Hospitalar de Vila Nova de Gaia
2024
Universidade Brasil
2018-2023
Hospital Braga
2023
National Medical Research Center of Dentistry and Maxillofacial Surgery
2022
Abstract Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological and molecular characteristics limiting the standard tumor−node−metastasis prognosis classification. Therefore, defining biological signatures that allow assessing prognostic outcomes for OSCC patients would be great clinical significance. Using histopathology-guided discovery proteomics, we analyze neoplastic islands stroma from invasive tumor front (ITF) inner to identify differentially...
Abstract The development and progression of oral cavity squamous cell carcinoma (OSCC) involves complex cellular mechanisms that contribute to the low five-year survival rate approximately 20% among diagnosed patients. However, biological processes essential tumor are not completely understood. Therefore, detecting alterations in salivary proteome may assist elucidating modulated OSCC improve clinical prognosis disease. whole saliva extracellular vesicles (EVs) from patients with healthy...
Aims: Polymorphous low‐grade adenocarcinoma of the minor salivary glands is an infiltrative neoplasm characterized by bland‐looking tumour cells arranged in diverse architectural patterns. It considered to be malignant potential that nodal metastases are seen only a minority, and distant spread rare. Even more unusual transformation polymorphous histologi‐cally high‐grade carcinoma, i.e. dedifferentiation. In this paper, we describe clinicopathological immunohistochemical findings two...
Head and neck cancers, including oral squamous cell carcinoma (OSCC), are the sixth most common malignancy in world characterized by poor prognosis a low survival rate. Saliva is fluid with intimate contact OSCC. Besides non‐invasive, simple, rapid to collect, saliva potential source of biomarkers. In this study, we build an SRM assay that targets fourteen OSCC candidate biomarker proteins, which were evaluated set clinically‐derived samples. Using Skyline software package, demonstrated...
While altered protein glycosylation is regarded a trait of oral squamous cell carcinoma (OSCC), the heterogeneous and dynamic glycoproteome tumor tissues from OSCC patients remain unmapped. To this end, we here employ an integrated multi-omics approach comprising unbiased quantitative glycomics glycoproteomics applied to cohort resected primary with (n = 19) without 12) lymph node metastasis. all displayed relatively uniform N-glycome profiles suggesting overall stable global N-glycosylation...
This study aimed to explore perceived barriers early diagnosis and management of oral cancer, as well potential pathways for improvement in Latin America the Caribbean (LAC).
Santos-Silva A R, Ribeiro C P, Soubhia M Miyahara G I, Carlos Speight P M, Hunter K D, Torres-Rendon A, Vargas & Lopes (2011) Histopathology 58, 1127–1135High incidences of DNA ploidy abnormalities in tongue squamous cell carcinoma young patients: an international collaborative study Aims: This multi-centre analysis assessed the content TSCC 37 patients (<40 years) and 28 old (>50 determined correlation findings with clinicopathological data. Methods results: Image cytometry was carried out...
Amyloidosis is associated with or caused by amyloid deposition. These fibrillar proteins may be deposited extracellularly causing tissue damage impairment.The aim of the study was to retrospectively review pathology archives in two oral diagnostic centers for cases fulfilling criteria amyloidosis and differentiate AA AL types amyloidosis.The clinicopathological features, alkaline Congo red staining, without pretreatment potassium permanganate, immunohistochemical (IHC) staining anti-AA,...