A5008367443- Oral and Maxillofacial Pathology
- Bone Tumor Diagnosis and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Tumors and Oncological Cases
- Sarcoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Ear and Head Tumors
- Cutaneous Melanoma Detection and Management
- Soft tissue tumor case studies
- Head and Neck Cancer Studies
- Lymphoma Diagnosis and Treatment
- Cancer and Skin Lesions
- Oral Health Pathology and Treatment
- Cervical Cancer and HPV Research
- Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Infectious Diseases and Mycology
- Vascular Malformations and Hemangiomas
- Histiocytic Disorders and Treatments
- Mycobacterium research and diagnosis
- Cancer-related molecular mechanisms research
- Bone and Dental Protein Studies
- Oral and Craniofacial Lesions
- Bone health and treatments
- Oral and gingival health research
Centro de Epilepsia y Neurocirugía Funcional
2004-2025
University of Pretoria
2022
Hospital Universitario Reina Sofía
2020-2021
Centro Dermatológico Federico Lleras Acosta
2015-2021
Unidad de Cirugía Cardiovascular de Guatemala
2003-2020
Oregon Health & Science University
2017
Methodist University of Piracicaba
2017
Universidade Estadual de Campinas (UNICAMP)
2017
Indiana University – Purdue University Indianapolis
2017
Long Island Jewish Medical Center
2014
The combination of recessively inherited cone-rod dystrophy (CRD) and amelogenesis imperfecta (AI) was first reported by Jalili Smith in 1988 a family subsequently linked to locus on chromosome 2q11, it has since been second small family. We have identified five further ethnically diverse families cosegregating CRD AI. Phenotypic characterization teeth visual function the published new reveals consistent syndrome all seven families, link or are with linkage confirming existence genetically...
Santos-Silva A R, Ribeiro C P, Soubhia M Miyahara G I, Carlos Speight P M, Hunter K D, Torres-Rendon A, Vargas & Lopes (2011) Histopathology 58, 1127–1135High incidences of DNA ploidy abnormalities in tongue squamous cell carcinoma young patients: an international collaborative study Aims: This multi-centre analysis assessed the content TSCC 37 patients (<40 years) and 28 old (>50 determined correlation findings with clinicopathological data. Methods results: Image cytometry was carried out...
Aims To assess the DNA content of cases oral proliferative verrucous leukoplakia ( PVL ) and correlate ploidy findings with expression M cm2, geminin, K i67, clinicopathological data. Methods results quantification was performed by image cytometry using ACIS III A utomated C ellular I maging S ystem. Expression cm2 geminin determined immunohistochemistry. There were 21 , female/male ratio 6:1, average age 65.5 years. Seventeen patients (81.0%) did not report tobacco alcohol consumption. Nine...
Abstract Background Focal epithelial hyperplasia (FEH) is a rare oral HPV‐related disease, highly prevalent in certain ethnic communities. A previous study found 7.5% prevalence among school children from the Indian community Embera‐Chamí Colombia. Objective To determine and Human Papillomavirus (HPVs)‐type with FEH. Materials methods One hundred thirty‐eight students were screened. All FEH samples HPV‐tested by two PCR‐based systems. Results We identified 18 cases. β‐globin amplification...
Amyloidosis is associated with or caused by amyloid deposition. These fibrillar proteins may be deposited extracellularly causing tissue damage impairment.The aim of the study was to retrospectively review pathology archives in two oral diagnostic centers for cases fulfilling criteria amyloidosis and differentiate AA AL types amyloidosis.The clinicopathological features, alkaline Congo red staining, without pretreatment potassium permanganate, immunohistochemical (IHC) staining anti-AA,...
Verruciform xanthoma of the oral cavity is an uncommon benign lesion that usually affects palate and gingiva mainly as a well-circumscribed solitary yellowish to whitish plaque or nodule, which promptly recognized microscopically by identification sub-epithelial foamy macrophages. The aim this study was evaluate clinicopathologic immunohistochemical features 20 cases verruciform xanthoma. All were evaluated conventional hematoxylin/eosin staining six those submitted reactions for CD68, CD63,...
We investigated the reliability of combined DOG1 and mammaglobin immunohistochemistry compared with ETV6 fluorescence in situ hybridization (FISH) assessment salivary tumors previously diagnosed as acinic cell carcinoma (ACC). Ultrastructural features cases reclassified mammary analogue secretory (MASC) were assessed by transmission electron microscopy (TEM).Immunohistochemical (IHC) reactivity to was validated against FISH targeting gene all 14 cases.Three papillary cystic histomorphology...
The aim of this study was to analyze the histopathological and immunohistochemical characteristics 22 cases primary oral melanomas (OM).Twenty two melanoma were analyzed by description their features using antibodies S-100, HMB-45, Melan-A Ki-67.The mean age 58 years 14 female. main affected sites hard palate, followed upper gingiva. Microscopically, 15 presented level III invasion, 2 amelanotic 13 showed a mixed epithelioid plasmacytoid or spindle cells composition. Some necrosis,...
The aim of this study was to determine the expression fatty acid synthase (FASN) in oral nevi and melanomas, comparing results with correspondent cutaneous lesions.Expression FASN evaluated by immunohistochemistry 51 melanocytic lesions, including 38 intramucosal 13 primary 10 14 melanomas.Fatty strongly expressed only either mucosa or cutaneous. On other hand, most were negative, a few cases showing focal weak expression.Fatty is malignant melanocytes, it can be helpful marker distinguish...
Background Pilomatrixoma, craniopharyngioma, and calcifying cystic odontogenic tumor are the main entities presenting ghost cells as an important histological feature, in spite their quite different clinical presentation; it seems that they share a common pathway formation of these cells. The aim this study is to examine compare characteristics other form lesions. Methods Forty‐three cases including 21 pilomatrixomas, 14 craniopharyngiomas, eight tumors were evaluated by immunohistochemistry...
ABSTRACT Background Rhabdomyosarcoma (RMS), a rare malignant tumor, frequently affects pediatric patients, with 35%–40% occurring in the head and neck. This study analyzes clinicopathologic profile of neck rhabdomyosarcomas from Brazil, Guatemala, Mexico, South Africa. Methods We reviewed 44 cases 10 Oral Maxillofacial Pathology services, conducting immunohistochemical analyses desmin, myogenin, Myo‐D1, Ki67, quantification via QuPath software. Cases ≥ 50% myogenin expression were tested for...