Nihal Demirel

ORCID: 0000-0003-2044-2212
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About
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Research Areas
  • Neonatal Respiratory Health Research
  • Neonatal Health and Biochemistry
  • Congenital Diaphragmatic Hernia Studies
  • Infant Development and Preterm Care
  • Neuroscience of respiration and sleep
  • Metabolism and Genetic Disorders
  • Infant Nutrition and Health
  • Retinopathy of Prematurity Studies
  • Neonatal and Maternal Infections
  • Congenital Heart Disease Studies
  • Neonatal and fetal brain pathology
  • Genetic and rare skin diseases.
  • Sepsis Diagnosis and Treatment
  • Pediatric Hepatobiliary Diseases and Treatments
  • Streptococcal Infections and Treatments
  • Methemoglobinemia and Tumor Lysis Syndrome
  • Birth, Development, and Health
  • RNA regulation and disease
  • Heme Oxygenase-1 and Carbon Monoxide
  • Craniofacial Disorders and Treatments
  • Intestinal Malrotation and Obstruction Disorders
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Breastfeeding Practices and Influences
  • Gestational Diabetes Research and Management
  • Congenital Ear and Nasal Anomalies

Ankara Yıldırım Beyazıt University
2018-2025

Mayo Clinic in Florida
2024

Bilkent University
2023

Sağlık Bilimleri Üniversitesi
2019-2023

Zübeyde Hanim Maternity Hospital
2014-2023

Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi
2014-2020

University of Health Sciences
2019

Ministry of Health
2017

Eskişehir Osmangazi University
2017

Ankara University
2017

Background To evaluate the prevalence, risk factors and treatment of retinopathy prematurity (ROP) in Turkey to establish screening criteria for this condition. Methods A prospective cohort study (TR-ROP) was performed between 1 April 2016 30 2017 69 neonatal intensive care units (NICUs). Infants with a birth weight (BW)≤1500 g or gestational age (GA)≤32 weeks those BW>1500 GA>32 an unstable clinical course were included study. Predictors development ROP determined by logistic...

10.1136/bjophthalmol-2017-311789 article EN cc-by-nc British Journal of Ophthalmology 2018-03-08

Hypoxic ischemic encephalopathy (HIE) is a significant cause of mortality and short- long-term morbidities. Therapeutic hypothermia (TH) has been shown to be the standard care for HIE infants ≥36 weeks gestational age (GA), as it demonstrated reduce rates mortality, adverse neurodevelopmental outcomes. This study aims determine incidence in our country, assess TH management with HIE, present short-term outcomes these infants.The Turkish Ischemic Encephalopathy Online Registry database was...

10.1371/journal.pone.0295759 article EN cc-by PLoS ONE 2023-12-14

Objective: Preterm premature rupture of membranes (PPROM), associated with prematurity, is an important obstetric complication that may cause neonatal mortality and morbidity. The optimal delivery time controversial in cases the expectant approach. fetal effects long-term exposure to PPROM are unknown. This study aimed evaluate maternal outcomes expectantly-managed different latency periods at 240/7–346/7 weeks gestation.Material method: group consisted 206 patients gestation who met...

10.1080/14767058.2020.1731465 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2020-02-23

Objective: Surfactant therapy (ST) is commonly used in late preterm (LPT) infants with respiratory distress despite a lack of definitive recommendation for these infants. Our aim was to establish national prospective database evaluate the use surfactants LPT Materials and Methods: A multicenter, observational cohort study conducted among treated surfactant between January 1, 2022, December 31, 2022. Twenty neonatologists from 16 neonatal intensive care units (NICUs) participated study....

10.5152/turkarchpediatr.2025.24236 article EN cc-by-nc Turkish Archives of Pediatrics 2025-03-10

There are few data with respect to prothrombotic risk factors in neonates.To determine the associated factors, clinical features and outcome newborn infants diagnosed thrombo-embolism.Case records of 25 (17 full-term eight preterm) thrombo-embolism between January 2005 April 2008 a neonatal intensive care unit were reviewed.Of infants, 18 cases venous (72%) seven arterial (28%) recorded; it was central catheterisation. The sites thrombosis portal vein (15), right renal (one), femoral...

10.1179/027249309x12547917868961 article EN Annals of Tropical Paediatrics 2009-11-18

No consensus has been reached on which patent ductus arteriosus (PDAs) in preterm infants require treatment and if so, how when they should be treated. A prospective, multicenter, cohort study was conducted to compare the effects of conservative approaches medical options ductal closure at discharge, surgical ligation, prematurity-related morbidities mortality. Infants between 240/7–286/7 weeks gestation from 24 neonatal intensive care units were enrolled. Data PDA management patients'...

10.3389/fped.2020.00434 article EN cc-by Frontiers in Pediatrics 2020-07-31

A 4-day-old neonate presented with respiratory distress owing to chest wall deformity associated metabolic bone disease. He was found have congenital hyperparathyroidism and his mother suffering from post-surgical hypoparathyroidism vitamin D deficiency. The patient given calcium lactate maintenance doses of D. subsided, the parathyroid hormone level returned normal by 4 weeks age mineral content had improved. Congenital should be considered in neonates presenting deformity.

10.1179/146532809x440770 article EN Annals of Tropical Paediatrics 2009-05-18

We investigated adiponectin levels in women with gestational diabetes mellitus (GDM) and normal glucose tolerance (NGT) at 24-28 weeks. Fasting serum adiponectin, glycated haemoglobin (HbA1c) were determined 88 pregnant women, 44 GDM NGT. Pre-pregnancy current body mass indices (BMI), weight gain pregnancy outcomes investigated. Serum was significantly reduced compared the NGT group (p = 0.000). Adiponectin negatively correlated age (r -0.419, p 0.000); -0.263, 0.013); HbA1c -0.274, 0.01);...

10.3109/01443615.2014.902430 article EN Journal of Obstetrics and Gynaecology 2014-04-16

Bart’s syndrome is characterized by aplasia cutis congenita and epidermolysis bullosa. We present the case of a newborn male who developed blisters on mucous membranes skin following congenital localized absence skin. (BS) diagnosed clinically based disorder’s unique signs symptoms but histologic evaluation can help to confirm final diagnosis. The patient was managed conservatively with topical antibacterial ointment wet gauze dressing. Periodic follow-up examinations showed complete...

10.1155/2015/549825 article EN cc-by Case Reports in Dermatological Medicine 2015-01-01

<b>Background</b> Retinopathy of prematurity (ROP) is a significant cause childhood blindness. <b>Aim</b> The aim this study to determine the feasibility remifentanil analgesia during laser treatment ROP performed in neonatal intensive care unit (NICU). <b>Patients and Methods</b> Remifentanil was infused continuously procedure starting with dose 0.2 µg/kg/min increased gradually 0.6 provide an adequate level analgesia. <b>Results</b> We enrolled 64 infants. at mean rate 0.4 ± 0.1 μg/kg/min....

10.1055/s-0034-1370348 article EN American Journal of Perinatology 2014-05-02

Objective: We examined the morbidities and oxidative stress statuses in preterms receiving either SMOFlipid or ClinOleic.Study design: This observational study was performed Etlik Zubeyde Hanim Hospital, Turkey. Infants received (5 months) ClinOleic (7 months). Two hundred twenty seven infants (SMOFlipid: 93, ClinOleic: 134) very low birth weighted were included. The status evaluated at risk of by total antioxidant capacity (TAC) oxidant (TOS) index (OSI; TAC/TOS/100) baseline, first week...

10.1080/14767058.2017.1300644 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2017-03-15

Abstract Objective A temporal relationship has been reported between necrotizing enterocolitis, anemia, and red blood cell transfusion (RBCT) in preterm neonates. However, the mechanism underlying this association is not clearly defined. Intestinal (I-) liver (L-) fatty acid binding proteins (FABPs) have proposed as plasma markers for detection of acute intestinal injury. This study aimed to investigate effect anemia RBCT on injury neonates by measuring serum I-FABP L-FABP levels. Study...

10.1055/s-0039-1683982 article EN American Journal of Perinatology 2019-04-04

Objective To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from intensive care units (NICUs) in Turkey. Material and methods A prospective cohort study was performed between April 1, 2016 30, 2017. The included VLBW admitted to level III NICUs. Perinatal data all born with a birth weight ≤1500 g were collected for who survived. Results Data 69 NICUs obtained. mean gestational age 1137±245 29±2.4 weeks, respectively. During period, 78%...

10.1371/journal.pone.0226679 article EN cc-by PLoS ONE 2019-12-18

Ocular hemorrhages (OHs) may cause visual disturbances and incidence vary from 18 to 39% in newborns. Precipitated/instrumental delivery perinatal asphyxia were predefined risk factors. Acidosis can interfere with coagulation disrupt the pressure of ocular capillaries put infants moderate acidosis or without hypoxic-ischemic encephalopathy at for OH. We aimed evaluate OH neonates fetal acidosis.

10.1055/s-0044-1780512 article EN American Journal of Perinatology 2024-02-16

Özcan B, Kavurt AS, Aydemir Ö, Gençtürk Z, Baş AY, Demirel N. SNAPPE-II and risk of neonatal morbidities in very low birth weight preterm infants. Turk J Pediatr 2017; 59: 105-112. Illness severity scores were described to estimate the mortality morbidity risks based on data obtained shortly after admission an intensive care unit. The aim this study is evaluate Scores for Neonatal Acute Physiology-Perinatal Extension-II (SNAPPE-II) as a predictors such bronchopulmonary dysplasia (BPD)...

10.24953/turkjped.2017.02.001 article EN The Turkish Journal of Pediatrics 2017-04-25

Abstract Background Preterm infants are scheduled to receive total feeding amount in either 3‐hour or 2‐hour intervals. A gavage may be required if the is not completed orally. Feedings every 2 hours one‐third smaller than feedings 3 hours. Thus, volume of each feed reduced by decreasing interval from hours, likelihood that infant completes orally increases, and probability requiring decreases. The impact with intervals on time achieve full oral preterm was investigated. Methods Infants...

10.1002/ncp.10244 article EN Nutrition in Clinical Practice 2019-01-15
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