A5102753745- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Spanish Literature and Culture Studies
- Early Modern Spanish Literature
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Historical Studies on Spain
- Cancer Treatment and Pharmacology
- Prostate Cancer Treatment and Research
- Body Contouring and Surgery
- Wound Healing and Treatments
- Historical Art and Architecture Studies
- Reconstructive Surgery and Microvascular Techniques
- Burn Injury Management and Outcomes
- Cinema History and Criticism
- Bladder and Urothelial Cancer Treatments
- Comparative Literary Analysis and Criticism
- Cultural and Mythological Studies
- Radiopharmaceutical Chemistry and Applications
- Economic and Financial Impacts of Cancer
- Photographic and Visual Arts
- Medieval and Early Modern Iberia
- Historical and Literary Analyses
- Cultural and Social Studies in Latin America
- Historical and Modern Theater Studies
Hospital Arnau de Vilanova
2012-2025
Hospital Juárez de México
2025
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
2020-2025
Hospital Universitari Arnau de Vilanova
2017-2025
Hospital Clínic de Barcelona
2023
Hospital Universitari i Politècnic La Fe
1992-2022
AstraZeneca (United Kingdom)
2021
Centre Hospitalier de Tourcoing
2021
Hospital Universitario Doctor Peset
2018-2020
Spanish Ovarian Cancer Research Group
2020
142 Background: Darolutamide, enzalutamide or apalutamide have demonstrated to prolong overall survival in patients with non-metastatic castration-resistant prostate cancer (nmCRPC). Despite their effectiveness, almost all progress mCRPC. In the last few years, several new options for treatment of advanced shown benefit. Darolutamide showed significantly prolonged metastasis-free compared placebo nmCRPC ARAMIS phase III trial. There is a lack data about patterns that after receiving...
720 Background: Urothelial cancer (UC) is the tenth most common globally. Standard first-line treatment for metastatic UC (mUC) involves enfotumab-vedotin + pembrolizumab or platinum-based chemotherapies, but some patients are ineligible to standard due significant comorbidities and poor performance status. Atezolizumab, an immune checkpoint inhibitor, has shown activity in clinical trials. This study evaluates real-world effectiveness safety of atezolizumab as a with locally advanced...
4588 Background: Combined-modality treatments are bladder-preserving alternatives for patients (pts) who not candidates radical cystectomy by medical reasons, refusal, or patient´s choice. Immune therapies seem to potentiate tumor-specific immune response induced radiotherapy (RT). Combination of RT with anti-PD-1/PD-L1 therapy appears safe and there signs promising activity. The aim this study is assess the efficacy safety atezolizumab (ATZ) concurrent external beam (EBRT) treatment...
In this study, absorption capacity of the most commonly used types wound dressings was measured with an objective, quantifiable, and easily reproducible method. The use objective measurements allowed us to perform comparison different dressings. An experimental study performed, in which absorptive polyurethane foams, alginate, hidrofiber, hydrocolloid by using a methodology designed researchers. Polyurethane foams showed higher than hidrofibers, alginates, hydrocolloids when similar surface...
Studies of patients with cancer affected by coronavirus disease 2019 (COVID-19) are needed to assess the impact in this sensitive population, and influence different treatments on COVID-19 infection seroconversion.We performed a retrospective analysis all hospitalized RT-PCR positive for our region prevalence describe their characteristics evolution (Cohort 1). Concurrently, transversal study was carried out active systemic treatment symptomatology seroprevalence (IgG/IgM ELISA-method)...
7055 Background: Significant interaction between XRCC1 genotype and age has been reported, with younger subjects having a greater risk of developing lung cancer. Carriers XRCC3 241 MetMet have higher levels DNA adducts, leading us to hypothesize that they would be more chemosensitive, especially patients. Methods: Real-time PCR assay was used determine from isolated baseline blood samples 878 stage IV NSCLC p (162 treated gem/cis; 716 doc/cis). Median age, 60; 266 (30%) <55; 239 (39%)...
Abstract Disruption of patellar tendon after total knee arthroplasty (TKA) is a devastating complication. If associated with infection or soft tissue defect, arthrodesis usually indicated. The purpose this study to analyze, by means an anatomical study, the feasibility our novel technique for reconstruction extensor apparatus TKA infections skin defects, combining gracilis (G) and semitendinosus (ST) autografts chimeric medial gastrocnemius-sural artery perforator (SAP) flap. In addition,...
This study investigated the use of endonasal infiltrative anesthesia for management pain associated with nasal bone fracture reduction. Fifty-two patients fractures were distributed in 2 groups. In first group, topical and external transcutaneous employed. second was also added. Visual analog scale scores related to different steps procedure registered. The addition a significant decrease (p < .05) during reduction maneuvers (6.71 vs. 4.83) packing (5.18 3.46). Addition is an effective...
Bacterial translocation is an important phenomenon in clinical medicine and leads to increase patient morbidity mortality by multiple organ failure. The selectin family plays role the pathogenesis of inflammation, causing leukocyte-endothelium interactions inducing a greater leukocyte's migration. This study considered effect sulfo derivative Sialyl-Lewis(X), GM 1998-016, that will block P- E-selectins interaction with ligand, valuing modulation systemic inflammatory response induced...
7053 Background: SNPs are the result of historical errors in DNA replication or repair that have been inherited through generations and now shared among individuals. ERCC1 belongs to nucleotide excision pathway. We examined whether 118 C/T C8092A affect cis lesions thereby influence survival cis-treated NSCLC p. Methods: SNP genotyping 118C/T was performed by TaqMan assay, results were correlated with median (MS) 706 cis/doc-treated stage IV Results: Characteristics: 590 male, 116 female;...
Abstract Facial paralysis is a condition caused by wide variety of etiologies, including neurologic, congenital, infectious, neoplastic, systemic, and iatrogenic causes. A patient suffering from long-term facial paralysis, with minimal innervation detected through electroneurography, who was successfully reanimated performing masseter-to-facial nerve transfer, presented in this study. had been after resection an acquired middle ear cholesteatoma more than 5 years before.
Some interesting plants from Eastern Andalusia II ( Malaga- Granada) Palabras clave. Flora, Andalucía, España. Key words. Andalusia, Spain.
4592 Background: Combined-modality treatments (CMTs) are bladder-preserving alternatives for patients (pts) ineligible radical cystectomy. CMTs combine maximal transurethral resection (TUR) of bladder tumor, radiotherapy (RT), and chemotherapy. Emerging immune therapies seem to enhance RT-induced tumor-specific response. RT combined with anti-PD-1/PD-L1 therapy shows promising efficacy acceptable toxicity. This ongoing study evaluates the safety atezolizumab (ATZ) concurrent external beam...
6089 Background: Febrile neutropenia (FN), a dose-limiting event for many myelosuppressive chemotherapy (CT) regimens, often causes subsequent CT dose delays (DD) and reductions (DR), lengthens hospital stay increases monitoring, diagnostic treatment costs. No studies are known to date on economic costs of FN in common clinical practice Spain. Methods: This is multicentre, retrospective, observational chart review adult patients with breast cancer, lung cancer or non-Hodgkin’s lymphoma (NHL)...
e18036 Background: Patients (p) with advanced NSCLC have few treatment options after progressing to 1st-line platinum doublet chemotherapy (PDC). Several preclinical and phase I studies suggested that sequential administration of erlotinib (E) docetaxel could avoid possible negative interactions optimize the benefit obtained against NSCLC. This randomized II was designed address clinical use intermittent E. Methods: 70 p previous PDC for disease were (1:1): Group A (n = 34): Docetaxel 75...