The aim of this research was to evaluate the process bone regeneration in rabbits, using chitosan and beta-tricalcium phosphate (β-TCP) independently combination. A total 12 New Zealand rabbits both sexes, with average weight 3.0 ± 0.57 kg were used. Animals randomly divided into two experimental time points, six animals euthanized 45 days after surgery 90 surgery. We performed osteotomies each tibia. left tibia used for (QUI) control groups, right β-TCP alone combination (QUI+TCP) groups....

The search for an effective and long-lasting strategy to treat osteochondral defects (OCD) is a great challenge. Regenerative medicine launched new era of research in orthopaedics restoring normal tissue functions. aim this study was test the healing potential Rigenera micrografting technology rat model OCD by investigating 2 cartilage donor sites.Full-thickness bilaterally created knee joints rats. Animals were randomly divided into groups based on anatomical site used micrograft...

A tomografia computadorizada quantitativa (TCQ) é uma técnica com alta sensibilidade, aplicabilidade e precisão no diagnóstico de perda massa óssea, entretanto a falta valores normalidade para animais silvestres limita sua aplicação clínica. O presente estudo objetiva estabelecer médios radiodensidade do osso trabecular das vértebras dorsais, pleural neural tartarugas marinhas juvenis hígidas utilizando TCQ. Para isso, utilizou-se um grupo experimental cinco que foram submetidos exames...

The aim of this study is to evaluate the possible alterations in radiodensity hepatic parenchyma and spleen resulting from corticotherapy with prednisone, correlating these findings serum biochemical transaminase activity. A clinical trial was performed on eight healthy dogs intent evaluating after prednisone therapy using quantitative computed tomography. All animals received orally at a dose 2mg/kg weight for 30 days. liver determined before period that medication administered. An increase...

Testou-se a hipótese de o alo-transplante bexiga devolver capacidade estrutural e funcional desse órgão, usando-se 10 cães machos, saudáveis, submetidos à cistectomia parcial com preservação do trígono vesical. Utilizou-se na reconstrução da vesícula urinária acompanhamento dos animais durante 60 dias. Aos oito dias pós-operatório, os apresentavam contenção micção espontânea. Houve aumento gradativo volume urinária, alcançando, aos dias, valores significativamente mais altos que observados...

The indiscriminate use of Anabolic Androgenic Steroids (AAS) causes harm to several systems such as reproductive, hepatic, skeletal muscle, endocrine, renal, cardiovascular and dermatological. Therefore, the present study aims investigate effects on morphology heart sedentary rats athletic using stanozolol. For this purpose, 40 male Wistar rats, 90 days old, were used, subdivided into four vehicle control groups (CV), treated with stanozolol (CT), exercise (EV) group (ET). Stanozolol was...

Os esteróides anabólicos androgênicos (EAA), derivados sintéticos da testosterona, têm diversas aplicações clínicas, incluindo a terapia de reposição testosterona. No entanto, seu uso indiscriminado por atletas e frequentadores academia em busca melhor desempenho físico estética corporal pode resultar várias alterações patológicas, como hipogonadismo oligospermia. Este estudo teve objetivo avaliar as possíveis morfofisiológicas ocasionadas pela dose suprafisiológica do estanozolol (ST) ratos...

Este trabalho tem como objetivo avaliar a eficácia do Trabalho Dirigido, uma metodologia ativa, facilitador aprendizado na disciplina de Fisiologia Especial dos Animais Domésticos para estudantes graduação em medicina veterinária. A pesquisa justifica-se pela complexidade da fisiologia animal, que demanda compreensão prévia diversas disciplinas e abordagem crítica sobre os processos orgânicos. atuação professor é essencial identificar resolver as dificuldades alunos, tornando o conhecimento...

Mesenchymal stem cells (MSCs), undifferentiated with high proliferative potential, are present in small quantities bodily secretions and various adult tissues. Their broad distribution lack of ethical concerns allow for their use diverse treatments, positioning them as a promising alternative to standard pharmaceutical therapies wound healing. Although the process obtaining culturing MSCs clinical application remains challenge, new technologies such Rigenera® simplify this stage, enabling...

Background: Pancreas cysts are liquid accumulations, rich in enzymes or blood, made by epithelial tissue of the affected organ, which grown for different causes, including injuries, neoplasms congenital diseases. In most cases, diagnosis is accidental, once patients can present nonspecific symptoms no evidence. Applying complementary exams, such as abdominal ultrasound and computed tomography, possible to visualize a structure located along pancreas topography, then promote patient's...

A regeneração dos componentes articulares configura-se como um grande desafio clínico devido aos aspectos morfofisiológicos intrínsecos tecidos relacionados, e a falha durante o processo reparativo pode ocasionar uma incapacidade funcional grave nas regiões afetadas. medicina regenerativa, baseada na utilização de células-tronco mesenquimais, vem exibindo potencial transpor as limitações vistas em tratamentos medicamentosos cirúrgicos disponíveis atualmente prática veterinária. Nesta...

Quantitative computed tomography was used to determine the radiodensity of bony plates. The CT scans provided information regarding plates and allowed verify uniformity bone mineral density in their scope. proposed methodology should be considered as another tool for determining resistance these biomaterials.

Endoscopy is a diagnosis method par excellence because it secure, fast and non-invasive, leading to benefits not reached by other methods in several digestive system diseases. Esophageal stricture usually occurs secondary esophagitis that results deep scar tissue formation. The main clinical sign regurgitation, right after feed intake. Diagnosis supported medical record, signs, esophagogram esophagoscopy. A 10-year-old mongrel dog presented dry food which bad began one year earlier, surgical...

Este estudo caracteriza a radiodensidade do cortex renal de 10 caes e gatos adultos, clinicamente saudaveis, por meio exames tomografia computadorizada helicoidal. Em cada rim, foi estimada pelo valor medio das tres regioes interesse na regiao cortical, selecionados no polo cranial, caudal hilo renal. A media nos foi, respectivamente, 28,4±4,7 22,4±3,6 unidades Hounsfield (HU). Verificou-se que os possuem hipoatenuante quando comparado com caes, um fato esta associado maior deposicao...

In the fetal nervous system training period faults can occur, leading to problems after birth, as persistence of fontanelle, which is due no calcification cranial sutures. Hydrocephalus a type genetic defect caused by inadequate circulation cerebrospinal fluid that build up promotes increased volume and consequent dilation cerebral ventricles. It be congenital or acquired, most predisposed breeds dogs are those small. Among common clinical signs hydrocephalus deformities in skull, eye...

Background: Coxofemoral dysplasia (CFD) is the abnormal development of hip joint, mostly affecting large breeds, and characterized by subluxation or complete luxation femoral head. Among conservative therapeutic options, cell therapies with stem cells for CFD provides potential countless possibilities application, especially those related to chronic and/or degenerative diseases treatment, which could be a key point bone joint repair. The objective was report bilateral case in dog, treated...

RESUMO Defeitos ósseos constituem um problema de saúde global. O sistema Rigenera permite a extração microenxertos ricos em células-tronco mesenquimais (CTMs). Objetivou-se avaliar o processo regeneração óssea por enxertos obtidos pelo defeitos críticos na calvária ratos. Foram utilizados 18 ratos Wistar, machos, pesando 285±29g, distribuídos três grupos (n=6), sendo cada animal controle si mesmo, denominados G15-Controle e G15-Tratado (15 dias); G30-Controle G30-Tratado (30 dias)...

Vaginal and vulvar neoplasms are the most common tumors in reproductive tract of bitches. This article describes case an eleven-year-old non-spayed Chow bitch with clinical signals ischuria, stranguria, fecal tenesmus. Ultrasonographic tomographic exams showed a mass within pelvic cavity that projected to caudal abdominal region displaced bladder cranially, partial obstruction urethra descending colon. fibroma was diagnosed after ultrasonography-guided biopsy histological analysis tissue...

This article discusses the use of platelet-rich fibrin as an alternative for treatment rotator cuff injuries. Recent studies show that these products reduces lesion recurrence and improves clinical outcomes. The purpose this study was to perform a systematic review in partial complete From initial search 703 articles on electronic platforms, seven were selected full reading inclusion. Simple arthroscopy most common type surgical intervention used. sample sizes ranged from minimum 20 maximum...

ABSTRACT: This study assessed the efficacy of an intra-articular injection allogeneic adipose tissue-derived from mesenchymal stem cells (AD-MSCs) for treatment hip dysplasia in dogs. The group included 12 otherwise healthy dogs different breeds, ages, weights, and degrees diagnosed using radiography. An orthopedic assessment was performed on all before at 30, 60, 90 days after infusion AD-MSCs(2 × 106cells). On same days, each dog’s owner answered a questionnaire based theHelsinkiChronic...