- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Ion Transport and Channel Regulation
- Hormonal Regulation and Hypertension
- Insect Pest Control Strategies
- Acute Kidney Injury Research
- Renal and related cancers
- Renin-Angiotensin System Studies
- Apelin-related biomedical research
- Electrolyte and hormonal disorders
- Insect and Pesticide Research
- Fatty Acid Research and Health
- Sodium Intake and Health
- Insect Resistance and Genetics
- Circadian rhythm and melatonin
- Stress Responses and Cortisol
- Meat and Animal Product Quality
- Hormonal and reproductive studies
- Diet, Metabolism, and Disease
- Muscle metabolism and nutrition
- Pregnancy and Medication Impact
- Pesticide Exposure and Toxicity
- Cardiovascular and exercise physiology
- Moringa oleifera research and applications
- Heme Oxygenase-1 and Carbon Monoxide
Universidade Federal de Pernambuco
2016-2025
Universidade Federal do Rio de Janeiro
2011-2024
National Institute of Science and Technology for Structural Biology and Bioimaging
2009-2024
National Institute of Science and Technology in Regenerative Medicine
2024
Objetivo. Descrever o perfil de praticantes musculação Pernambuco que fazem uso esteroides (EAA). Método. Trata-se um estudo descritivo transversal natureza quantitativa, realizado em 14 academias localizadas na região metropolitana Recife, Pernambuco. Foram aplicados 358 questionários com 15 itens referentes a dados sociodemográficos; tempo prática atividade física; consumo suplementos dietéticos; adesão dietas; dosagem e utilização do anabolizante administrado; conhecimento sobre os...
Ethnomedicinal studies in the Amazon community and Northeast region of Brazil highlight use Libidibia ferrea fruits for treatment gastric problems. However, there are no data literature this pharmacological activity. Thus, aim paper is to provide a scientific basis dry extract L. pods (DELfp) peptic ulcers. Phytochemical characterization was performed by HPLC/MS. In vitro antioxidant activity assessed using DPPH, ABTS, phosphomolybdenum, superoxide radical scavenging The gastroprotective...
Background Several studies have correlated perinatal malnutrition with diseases in adulthood, giving support to the programming hypothesis. In this study, effects of maternal undernutrition during lactation on renal Na+-transporters and local angiotensin II (Ang II) signaling cascade rats were investigated. Methodology/Principal Findings Female received a hypoproteic diet (8% protein) throughout lactation. Control programmed offspring consumed containing 20% protein after weaning....
Background Several studies have correlated protein restriction associated with other nutritional deficiencies the development of cardiovascular and renal diseases. The driving hypothesis for this study was that Ang II signaling pathways in heart kidney are affected by chronic protein, mineral vitamin restriction. Methodology/Principal Findings Wistar rats aged 90 days were fed from weaning either a control or deficient diet mimics those used impoverished regions worldwide. Such...
In the present study, we investigated development of hypertension in prenatally undernourished adult rats, including mechanisms that culminate dysfunctions molecular signalling kidney. Dams were fed a low-protein multideficient diet throughout gestation with or without α-tocopherol during lactation. The time course followed male offspring was correlated alterations proximal tubule Na+-ATPase activity, expression angiotensin II (Ang II) receptors, and activity protein kinases C A. After...
Summary Intrauterine malnutrition has been linked to the development of adult cardiovascular and renal diseases, which are related altered Na + balance. Here we investigated whether maternal increases placental oxidative stress with subsequent impact on ATP‐dependent transporters in offspring. Maternal was induced rats during pregnancy by using a basic regional diet available north‐eastern Brazil. Placental evaluated measuring thiobarbituric acid‐reactive substances, were 35–40% higher...
Prenatal malnutrition is responsible for the onset of alterations in renal Na(+) transport adult offspring. Here we investigated molecular mechanisms by which increased formation reactive oxygen species during prenatal affects pathways that couple angiotensin II (Ang II) receptors (AT(1)R and AT(2)R) to kidney Na(+)-ATPase adulthood, how maternal treatment with α-tocopherol can prevent main regulatory cascade pump. The experiments were carried out on progeny control malnourished dams...
Background: Tissue healing consists of four main phases: coagulation, inflammation, proliferation, and remodeling. In diabetic patients, this process is stagnant in the inflammatory stage, leading to chronic wounds. The aim study evaluate an animal model biological evidence related use Rigenera® technology (Turin Italy), innovative mechanical procedure isolate autologous micrografts (AMG). Methods: Fifty male Wistar rats were divided into groups: control (C), treated with (CM), (DB), (DBM)....
Exposure to the herbicides Paraquat and Roundup® may cause cell lesions due an increase in oxidative stress levels different biological systems, even liver. The aim of this study was analyze effect melatonin on liver rats exposed herbicides. A total 35 were randomly divided into seven equal-sized groups: control, Paraquat, Roundup®, + melatonin, melatonin. Samples blood hepatic tissue collected at end seventh day exposure treatment with Body weight, hematological parameters,...
Paraquat (1,1'-dimethyl-4,4'-bipyridyl dichloride) is an herbicide widely used worldwide and officially banned in Brazil 2020. Kidney lesions frequently occur, leading to acute kidney injury (AKI) due exacerbated reactive O2 species (ROS) production. However, the consequences of ROS exposure on ionic transport regulator local renin-angiotensin-aldosterone system (RAAS) still need be elucidated at a molecular level. This study evaluated how acutely influences Na+-transporting ATPases renal...
Background High Na+ intake is a reality in nowadays and frequently accompanied by renal cardiovascular alterations. In this study, mechanisms underlying perinatal overload-programmed alterations transporters the renin/angiotensin system (RAS) were investigated, together with effects of short-term treatment enalapril terms reprogramming molecular kidney. Methodology/Principal Findings Male adult Wistar rats obtained from dams maintained throughout pregnancy lactation on standard diet drinking...