Leucio Duarte Vieira Filho

ORCID: 0000-0002-6041-1720
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About
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Research Areas
  • Birth, Development, and Health
  • Pregnancy and preeclampsia studies
  • Ion Transport and Channel Regulation
  • Hormonal Regulation and Hypertension
  • Insect Pest Control Strategies
  • Acute Kidney Injury Research
  • Renal and related cancers
  • Renin-Angiotensin System Studies
  • Apelin-related biomedical research
  • Electrolyte and hormonal disorders
  • Insect and Pesticide Research
  • Fatty Acid Research and Health
  • Sodium Intake and Health
  • Insect Resistance and Genetics
  • Circadian rhythm and melatonin
  • Stress Responses and Cortisol
  • Meat and Animal Product Quality
  • Hormonal and reproductive studies
  • Diet, Metabolism, and Disease
  • Muscle metabolism and nutrition
  • Pregnancy and Medication Impact
  • Pesticide Exposure and Toxicity
  • Cardiovascular and exercise physiology
  • Moringa oleifera research and applications
  • Heme Oxygenase-1 and Carbon Monoxide

Universidade Federal de Pernambuco
2016-2025

Universidade Federal do Rio de Janeiro
2011-2024

National Institute of Science and Technology for Structural Biology and Bioimaging
2009-2024

National Institute of Science and Technology in Regenerative Medicine
2024

Objetivo. Descrever o perfil de praticantes musculação Pernambuco que fazem uso esteroides (EAA). Método. Trata-se um estudo descritivo transversal natureza quantitativa, realizado em 14 academias localizadas na região metropolitana Recife, Pernambuco. Foram aplicados 358 questionários com 15 itens referentes a dados sociodemográficos; tempo prática atividade física; consumo suplementos dietéticos; adesão dietas; dosagem e utilização do anabolizante administrado; conhecimento sobre os...

10.11606/issn.1981-4690.2022e36183189 article PT cc-by Revista Brasileira de Educação Física e Esporte 2022-07-25

Ethnomedicinal studies in the Amazon community and Northeast region of Brazil highlight use Libidibia ferrea fruits for treatment gastric problems. However, there are no data literature this pharmacological activity. Thus, aim paper is to provide a scientific basis dry extract L. pods (DELfp) peptic ulcers. Phytochemical characterization was performed by HPLC/MS. In vitro antioxidant activity assessed using DPPH, ABTS, phosphomolybdenum, superoxide radical scavenging The gastroprotective...

10.1155/2019/1983137 article EN cc-by Oxidative Medicine and Cellular Longevity 2019-11-20

Background Several studies have correlated perinatal malnutrition with diseases in adulthood, giving support to the programming hypothesis. In this study, effects of maternal undernutrition during lactation on renal Na+-transporters and local angiotensin II (Ang II) signaling cascade rats were investigated. Methodology/Principal Findings Female received a hypoproteic diet (8% protein) throughout lactation. Control programmed offspring consumed containing 20% protein after weaning....

10.1371/journal.pone.0021232 article EN cc-by PLoS ONE 2011-07-01

Background Several studies have correlated protein restriction associated with other nutritional deficiencies the development of cardiovascular and renal diseases. The driving hypothesis for this study was that Ang II signaling pathways in heart kidney are affected by chronic protein, mineral vitamin restriction. Methodology/Principal Findings Wistar rats aged 90 days were fed from weaning either a control or deficient diet mimics those used impoverished regions worldwide. Such...

10.1371/journal.pone.0100410 article EN cc-by PLoS ONE 2014-07-01

In the present study, we investigated development of hypertension in prenatally undernourished adult rats, including mechanisms that culminate dysfunctions molecular signalling kidney. Dams were fed a low-protein multideficient diet throughout gestation with or without α-tocopherol during lactation. The time course followed male offspring was correlated alterations proximal tubule Na+-ATPase activity, expression angiotensin II (Ang II) receptors, and activity protein kinases C A. After...

10.1017/s0007114513004236 article EN British Journal Of Nutrition 2014-03-24

Summary Intrauterine malnutrition has been linked to the development of adult cardiovascular and renal diseases, which are related altered Na + balance. Here we investigated whether maternal increases placental oxidative stress with subsequent impact on ATP‐dependent transporters in offspring. Maternal was induced rats during pregnancy by using a basic regional diet available north‐eastern Brazil. Placental evaluated measuring thiobarbituric acid‐reactive substances, were 35–40% higher...

10.1111/j.1440-1681.2009.05212.x article EN Clinical and Experimental Pharmacology and Physiology 2009-05-19

Prenatal malnutrition is responsible for the onset of alterations in renal Na(+) transport adult offspring. Here we investigated molecular mechanisms by which increased formation reactive oxygen species during prenatal affects pathways that couple angiotensin II (Ang II) receptors (AT(1)R and AT(2)R) to kidney Na(+)-ATPase adulthood, how maternal treatment with α-tocopherol can prevent main regulatory cascade pump. The experiments were carried out on progeny control malnourished dams...

10.1016/j.abb.2010.09.025 article EN publisher-specific-oa Archives of Biochemistry and Biophysics 2010-09-30

Background: Tissue healing consists of four main phases: coagulation, inflammation, proliferation, and remodeling. In diabetic patients, this process is stagnant in the inflammatory stage, leading to chronic wounds. The aim study evaluate an animal model biological evidence related use Rigenera® technology (Turin Italy), innovative mechanical procedure isolate autologous micrografts (AMG). Methods: Fifty male Wistar rats were divided into groups: control (C), treated with (CM), (DB), (DBM)....

10.3390/diabetology4030026 article EN cc-by Diabetology 2023-07-28

Exposure to the herbicides Paraquat and Roundup® may cause cell lesions due an increase in oxidative stress levels different biological systems, even liver. The aim of this study was analyze effect melatonin on liver rats exposed herbicides. A total 35 were randomly divided into seven equal-sized groups: control, Paraquat, Roundup®, + melatonin, melatonin. Samples blood hepatic tissue collected at end seventh day exposure treatment with Body weight, hematological parameters,...

10.1093/toxres/tfaa087 article EN Toxicology Research 2021-01-01

Paraquat (1,1'-dimethyl-4,4'-bipyridyl dichloride) is an herbicide widely used worldwide and officially banned in Brazil 2020. Kidney lesions frequently occur, leading to acute kidney injury (AKI) due exacerbated reactive O2 species (ROS) production. However, the consequences of ROS exposure on ionic transport regulator local renin-angiotensin-aldosterone system (RAAS) still need be elucidated at a molecular level. This study evaluated how acutely influences Na+-transporting ATPases renal...

10.1590/0001-3765202420230971 article EN cc-by Anais da Academia Brasileira de Ciências 2024-01-01

Background High Na+ intake is a reality in nowadays and frequently accompanied by renal cardiovascular alterations. In this study, mechanisms underlying perinatal overload-programmed alterations transporters the renin/angiotensin system (RAS) were investigated, together with effects of short-term treatment enalapril terms reprogramming molecular kidney. Methodology/Principal Findings Male adult Wistar rats obtained from dams maintained throughout pregnancy lactation on standard diet drinking...

10.1371/journal.pone.0043791 article EN cc-by PLoS ONE 2012-08-22
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