A5076730212- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Sodium Intake and Health
- Ion Transport and Channel Regulation
- Hormonal Regulation and Hypertension
- Cardiac electrophysiology and arrhythmias
- Dialysis and Renal Disease Management
- Blood Pressure and Hypertension Studies
- Acute Kidney Injury Research
- Heart Failure Treatment and Management
- Moringa oleifera research and applications
- Apelin-related biomedical research
- Ion channel regulation and function
- Cardiac Ischemia and Reperfusion
- Renal and Vascular Pathologies
- Renin-Angiotensin System Studies
- Venomous Animal Envenomation and Studies
- Electrolyte and hormonal disorders
- Muscle and Compartmental Disorders
- Cardiovascular Effects of Exercise
Universidade Federal de Pernambuco
2012-2024
Background High Na+ intake is a reality in nowadays and frequently accompanied by renal cardiovascular alterations. In this study, mechanisms underlying perinatal overload-programmed alterations transporters the renin/angiotensin system (RAS) were investigated, together with effects of short-term treatment enalapril terms reprogramming molecular kidney. Methodology/Principal Findings Male adult Wistar rats obtained from dams maintained throughout pregnancy lactation on standard diet drinking...
The Na+ -ATPase, a secondary pump in the proximal tubule, is only weakly responsive to angiotensin II adult offspring exposed perinatally high intake. We have investigated whether from mothers given 0.3 mol/L NaCl show an ineffective action increase blood pressure. It was hypothesized that functional alterations at life are associated with number of II-positive cells developing kidney, increased oxidative stress maternal/foetal organs, or morphometrical changes placentas. Wistar female rats...
Maternal endotoxemia disturbs the intrauterine environment, impairs nephrogenesis, and increases risk of hypertension kidney disease in adulthood. Here, it was investigated whether maternal treatment with water extract Moringa oleifera seeds (WEMoS) or water-soluble M. seed lectin (WSMoL) prevents oxidative stress induced by lipopolysaccharide (LPS) pregnant rats, renal injury adult offspring. The administration WEMoS WSMoL prevented stimulatory effects LPS on lipid peroxidation...
Abstract Maternal salt overload programs cardiovascular and renal alterations in the offspring. However, beneficial harmful effects of high dose vitamin E supplementation have been described humans animals. We investigated hypothesis as to whether cardiac can be programmed by gestational overload, become further modified during lactation after weaning. Male Wistar rats were used, being offspring mothers that drank either tap water or 0.3 mol/L NaCl for 20 days before pregnancy. α‐Tocopherol...