Robson Raion de Vasconcelos Alves

ORCID: 0000-0002-7539-0491
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Research Areas
  • Moringa oleifera research and applications
  • Fungal Infections and Studies
  • Pineapple and bromelain studies
  • Academic Research in Diverse Fields
  • Phytochemistry Medicinal Plant Applications
  • Apelin-related biomedical research
  • Protein Interaction Studies and Fluorescence Analysis
  • Natural product bioactivities and synthesis
  • Genital Health and Disease
  • Bee Products Chemical Analysis
  • Male Reproductive Health Studies
  • Business and Management Studies
  • Traditional and Medicinal Uses of Annonaceae
  • Pomegranate: compositions and health benefits
  • COVID-19 and healthcare impacts
  • Biochemical and Structural Characterization
  • Health, Education, and Cultural Studies
  • COVID-19 and Mental Health
  • Psidium guajava Extracts and Applications
  • Nail Diseases and Treatments
  • Rabbits: Nutrition, Reproduction, Health
  • Phytochemical compounds biological activities
  • Antifungal resistance and susceptibility
  • Studies on Chitinases and Chitosanases
  • Sperm and Testicular Function

Universidade Federal de Pernambuco
2020-2025

In this study, we purified and characterized a trypsin inhibitor (CvLTI) from the leaves of Cissus verticillata subsp. verticillata. CvLTI was isolated using trypsin-agarose column evaluated for stability towards heating (30 to 100 °C) incubation at different pH values (2.0 10.0). Furthermore, investigated antibacterial activity against phytopathogens, hemolytic as well cytotoxicity immunomodulatory effects on peripheral blood mononuclear cells (PBMCs). (14.3 kDa, pI 5.3) showed sequence...

10.1002/cbdv.202403287 article EN Chemistry & Biodiversity 2025-03-08

Plant extracts can be therapeutic alternatives for depression and anxiety. However, some plant-derived preparations also toxic. Moringa oleifera leaves are used in human nutrition due to their high nutritional value antioxidant activity. This study investigated a saline extract from M. (MoLE) secondary metabolites, proteins, cytotoxicity, hemolytic activity, vivo acute oral toxicity, neurobehavioral effects. MoLE contains flavonoids (rutin vitexin), lectin, trypsin inhibitor. It is neither...

10.3390/nutraceuticals4010005 article EN cc-by Nutraceuticals 2024-02-04

Moringa oleifera Lam. (horseradish tree) leaves demonstrate high nutritional value, are rich in proteins, and widely used folk medicine food. This study investigated the presence of secondary metabolites antinutritional proteins leaf extract (LE) protein-rich fraction (PRF) derived from M. leaves, as well cytotoxicity to human cells, hemolytic activity, vivo acute toxicity genotoxicity mice. The flavonoids rutin vitexin trypsin inhibitors lectins were detected LE PRF. Neither sample...

10.3390/ph17081045 article EN cc-by Pharmaceuticals 2024-08-08

Maternal endotoxemia disturbs the intrauterine environment, impairs nephrogenesis, and increases risk of hypertension kidney disease in adulthood. Here, it was investigated whether maternal treatment with water extract Moringa oleifera seeds (WEMoS) or water-soluble M. seed lectin (WSMoL) prevents oxidative stress induced by lipopolysaccharide (LPS) pregnant rats, renal injury adult offspring. The administration WEMoS WSMoL prevented stimulatory effects LPS on lipid peroxidation...

10.1590/0001-3765202420231266 article EN cc-by Anais da Academia Brasileira de Ciências 2024-01-01

This work reports the in vivo investigation of telluride cadmium quantum dots (CdTe QDs) conjugated to plant lectins from Schinus terebinthifolia (SteLL) and Punica granatum (PgTeL) for acute toxicity genotoxicity healthy mice 24-h biodistribution sarcoma 180-bearing animals. Acute data indicated their safety, despite some histopathological alterations. Comet assay revealed that QDs-PgTeL group presented a higher damage index frequency than negative control. The micronucleus test did not...

10.1080/01480545.2024.2433074 article EN Drug and Chemical Toxicology 2024-11-27

Cryptococcus is a genus of dimorphic basidiomycete fungi found in the form yeasts and filaments. Cryptococcosis has as main etiological agents species neoformans gattii. This disease considered public health problem becoming more alarming because limitations antimicrobials available to its treatment, addition an increase reports fungal resistance. In this sense, present review sought survey information on resistance mechanisms spp. against drugs used cryptococcosis therapy well antimicrobial...

10.33448/rsd-v10i2.12819 article EN Research Society and Development 2021-02-24

BACKGROUND: Semen cryopreservation is a biotechnology used frequently in animal production; however, there are some obstacles, such as those caused by high levels of reactive oxygen species (ROS). Moringa oleifera (MO) known potent source antioxidants and might be an important adjuvant . OBJECTIVE: The objective this study was to determine the effect different concentrations MO extract supplementation on goat semen efficiency. MATERIALS AND METHODS: Ejaculates (n=6) from four breeders were...

10.54680/fr23310110712 article EN Cryoletters 2023-05-01

No Brasil, mais de 80% dos casos hemofilia são do tipo A. A infusão concentrado Fator VIII (FVIII) pode desenvolver anticorpos neutralizantes. O tratamento escolha para indivíduos que desenvolveram inibidor é a imunotolerância (IT). Este estudo objetivou avaliar conduta e eficácia da IT em pacientes com grave na Fundação Hematologia Hemoterapia Pernambuco (HEMOPE), no período 2012 2017. foi descritivo uma abordagem quantitativa análise prontuários grave. total 17 hemofílicos grave, 47% ainda...

10.17921/1415-6938.2021v25n2p252-258 article PT Ensaios e Ciência C Biológicas Agrárias e da Saúde 2021-06-29
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