A5047181320- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- Pomegranate: compositions and health benefits
- Agricultural and Food Sciences
- Phytochemistry and Biological Activities
- Insect Pest Control Strategies
- Bioactive Natural Diterpenoids Research
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Microencapsulation and Drying Processes
- Psidium guajava Extracts and Applications
- Phytochemical compounds biological activities
- Curcumin's Biomedical Applications
- Ethnobotanical and Medicinal Plants Studies
- Oral health in cancer treatment
- Bee Products Chemical Analysis
- Antioxidants, Aging, Portulaca oleracea
- Carcinogens and Genotoxicity Assessment
- Migration, Racism, and Human Rights
- Plant tissue culture and regeneration
- Heavy Metals in Plants
- Moringa oleifera research and applications
- Plant-Derived Bioactive Compounds
- Geography and Environmental Studies
- Natural Antidiabetic Agents Studies
Universidade Federal de Pernambuco
2017-2025
This study aimed to provide a comprehensive understanding of the acute and subacute safety phytochemical profile pomegranate leaves, aligning with growing interest in sustainable, plant‐based therapeutics. The composition, toxicity spray‐dried hydroethanolic extract from leaves (SDE) were investigated using experimental animal models. Utilizing UV‐visible spectrophotometry liquid chromatography‐mass spectrometry (LC‐MS), diverse array tannins flavonoids, totaling 38 compounds, was...
In this study, the toxicity and antinociceptive effects of ethanolic extract Croton blanchetianus leaves were investigated in mice. Phytochemical analysis was performed by thin layer chromatography (TLC) high–performance liquid (HPLC) revealed presence alkaloids, reducing sugars, cinnamic derivatives, flavonoids, saponins, condensed tannins, terpenes, steroids. Acute evaluated administration a single dose 2000 or 5000 mg/kg b.w. (per os i.p.). The (50, 100, 200 per os) for genotoxicity...
Croton blanchetianus Baill, commonly known as "marmeleiro", is native to the Brazilian Caatinga traditional used treat joint pain and gastrointestinal disorders. The aim of study was identify chemical constituents by HPLC-DAD determine antioxidant activity spray-dried extract (SDE) aqueous (AqF) ethyl acetate (EAF) fractions obtained from leaves C. blanchetianus; acute (single dose, 2000 or 5000 mg/kg, p.o) subacute (repeated 250, 500 1000 toxicities, genotoxicity (1000 EAF in mice. In oral...
The chemical composition, the antioxidant and antimicrobial potential of crude extract from leaves Cinnamomum verum their enriched fractions was studied. Phytochemical analyses were performed by TLC HPLC, capacity verified DPPH• ABTS•+. Minimal Inhibitory/Bactericidal Concentration conducted against twenty-two bacteria to select five strains susceptible extracts/fractions resistant antibiotics tested. Interference Ethyl Acetate Fraction (EAF) in resistance synthetic antibiotic assayed...
The extracts of Spondias mombin leaves were obtained to study the influence drug amount and ethanol proportion on extract performance. optimized was dried by spray drying, contributions studied Box–Behnken design evaluate their drying yield product properties. factorial data indicated importance both factors responses optimal conditions employing 10 g herbal drug, 80% possible recovery high total polyphenols content (20.47 ± 0.08 g%), suitable dry residue (2.56 0.04 great extraction...
This work aimed to evaluate the chemical composition, antioxidant and antimicrobial activities from crude extract fractions leaves of Eugenia uniflora Linn. The was obtained by turbo extraction their partitioning. Chromatographic analysis were performed, capacity verified two methods (DPPH• ABTS•+). Minimal Inhibitory/Bactericidal Concentration conducted against twenty-two bacteria, selecting five strains susceptible extract/fractions resistant antibiotics tested. Ampicillin, azithromycin,...
Jacaranda rugosa (Bignoniaceae) is an endemic tree in Brazil with a limited distribution restricted to Caatinga. This study aimed evaluate ethanolic extracts of branches (BE) and leaves (LE) J. uncover the phytochemical profile using thin layer chromatography (TLC) high performance liquid (HPLC). In addition, were evaluated for antibacterial activity broth microdilution, antioxidant against free radicals DPPH ABTS+, oral acute toxicity (2000 mg/kg) mice, vivo anti-inflammatory effects...
The aim of this study was to evaluate the phytochemical composition, antioxidant, and antimicrobial potential crude extract fractions Punica granatum leaves. produced by turbo extraction, after which hexanic, ethyl acetate, aqueous were obtained partitioning. chemical analyses performed thin layer chromatography high-performance liquid chromatography, antioxidant activities assayed DPPH. ABTS.+ . Minimal inhibitory bactericidal concentrations (MIC/MBC) applied twenty-two bacteria. Most...
In this study was evaluated the influence of extraction factors on extract's properties to improve recovery high concentrations phytochemicals important for biological activities from pods Libidibia ferrea (Mart.ex Tul.) L. P. Queiroz.The extracts were obtained by turbo-extraction and a factorial design 3 2 used importance drug amount (5, 10 or 15 g) solvent (Ethanol 40, 60 80%, v/v) variables response, optimization performed Response Surface Methodology (RSM) Desirability...
In this study, we investigated the influence of mixture design on chemical profile Eugenia unifloraleaves, evaluating antioxidant and antimicrobial activities, toxic hemolytic potential, with focus improvement polyphenol’s extraction for incorporation extract in semi-solid forms antifungal action. The analysis was evaluated by UV-Vis HPLC. antimicrobial, antioxidant, activities were monitored. flavonoid content ranged from 2.63-7.98 %w/w tannins 5.42-18.29 %w/w. consisted gallic acid...
Currently, one of the main strategies to reduce incidence arboviruses such as Zika, dengue, and chikungunya is through population control their vector, Aedes aegypti. Lectins are carbohydrate-binding proteins with several biological properties, including insecticidal activity against A. Punica granatum sarcotesta contains a chitin-binding lectin (PgTeL), which prompted our evaluation its toxicity Here, we analyzed effects saline extract from P. PgTeL on survival aegypti larvae. Saline was...
Curcumin, contained at Turmeric (Curcumalonga), can exert many beneficial pleiotropic activities in the gastrointestinal tract. This study evaluated antioxidant and anti-inflammatory activity of C. longa on 5-fluorouracil (5-FU)-induced oral mucositis (OM) hamsters. Phytochemical analysis crude extract (CLE) was performed to detect presence curcumin by TLC HPLC. Golden Syrian hamsters were orally pre-treated with CLE (5, 50, or 100mg/kg). Cheek pouch samples subjected macroscopic...
The fruit of Spondias mombin (cajazeira) is widely consumed in the northeast region Brazil. In this work, three different extraction methods, namely ultrasound-assisted (UAE), turbo-extraction (TE) and pressurized hot water (PHWE), were evaluated order to investigate potential cajazeira leaves as an alternative source bioactive compounds. methods compared terms yield, chemical composition total phenolic content (TPC) extracts. highest yields TPC values obtained by TE with a mixture ethanol:...
The aim of this study is to demonstrate the stability-indicating capacity an analytical method for Eugenia uniflora, enhance understanding stability myricitrin, and assess effect degradation spray-dried extract (SDE) on antioxidant antifungal activities. Validation was carried out through a forced SDE standard myricitrin. activities were evaluated both before after degradation. quantification described found be accurate precise in measuring myricitrin levels from E. with excellent...
Acanthospermum hispidum DC (Asteraceae), popularly known as "espinho-de-cigano", is a plant species used in folk medicine to treat gastrointestinal and respiratory disorders. These activities can be related the presence of secondary metabolites, which also play toxicity. Considering that, objective this work was evaluate toxicity crude extract from roots A. hispidum. The herbal material collected, ground, obtained with acetone: water (7:3, v/v) at 10% (w/v) by turbo extraction. Phytochemical...
Phytochemical analysis of Croton blanchetianus leaves was performed by. After that, a high performance liquid chromatography method developed and validated for the determination rutin in herbal drug products C. blanchetianus. The separation achieved on C18 column, mobile phase composed ultrapure water methanol (acidified with trifluoroacetic acid) gradient 0.8 ml/min. following international guidelines. chemical revealed presence flavonoids. Among them used as standard validation. In HPLC...