- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- Phytochemistry and Bioactivity Studies
- Insect Pest Control Strategies
- Bee Products Chemical Analysis
- Moringa oleifera research and applications
- Bioactive Natural Diterpenoids Research
- Psidium guajava Extracts and Applications
- Phytochemicals and Antioxidant Activities
- Science and Education Research
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Botanical Research and Applications
- Phytochemistry and Bioactive Compounds
- Pain Mechanisms and Treatments
- Ethnobotanical and Medicinal Plants Studies
- Pomegranate: compositions and health benefits
- Plant biochemistry and biosynthesis
- Parasitic Diseases Research and Treatment
- Bioactive Compounds and Antitumor Agents
- Healthcare during COVID-19 Pandemic
- Hibiscus Plant Research Studies
- Papaya Research and Applications
- Healthcare Regulation
Universidade Estadual da Paraíba
2023-2025
Universidade Federal de Pernambuco
2015-2025
Faculdade Brasil
2019
Universidade Federal do Pará
2018
Morus alba L. (white mulberry) is used in traditional medicine worldwide, including Brazil. The leaves of this plant are to treat inflammatory disorders. Universal interest necessitates studies on the toxicological safety and scientific substantiation medicinal properties M. alba. In previous work, we investigated acute toxicity orally administered ethanol extract mice.This work was designed investigate obtained from for when intraperitoneally administered, vivo genotoxicity, potential...
This work evaluated an ethanolic extract from Morus alba leaves for toxicity to Artemia salina , oral mice, and antimicrobial activity. Phytochemical analysis revealed the presence of coumarins, flavonoids, tannins, triterpenes in extract, which did not show A. nauplii. No mortality behavioral alterations were detected mice treated with (300 2000 mg/kg b.w.) 14 days. However, animals that received highest dose showed reduced MCV MCHC as well increased serum alkaline phosphatase In treatments...
This study aimed to provide a comprehensive understanding of the acute and subacute safety phytochemical profile pomegranate leaves, aligning with growing interest in sustainable, plant‐based therapeutics. The composition, toxicity spray‐dried hydroethanolic extract from leaves (SDE) were investigated using experimental animal models. Utilizing UV‐visible spectrophotometry liquid chromatography‐mass spectrometry (LC‐MS), diverse array tannins flavonoids, totaling 38 compounds, was...
The plant Moringa oleifera is used as food and medicine. M. flowers are source of protein, fiber, antioxidants, to treat inflammation tumors. This work evaluated the antitumor activity flower trypsin inhibitor (MoFTI) in sarcoma 180-bearing mice. Swiss female mice were inoculated with 180 cells. Seven days later, animals treated intraperitoneally for 1 week daily doses PBS (control) or MoFTI (15 30 mg/kg). For toxicity assessment, water consumption, body organ weights, histological...
High-fat diet (HFD) consumption has been linked to dyslipidemia, low-grade inflammation and oxidative stress. This study investigated the effects of a mixed formulation with Limosilactobacillusfermentum 139, L. fermentum 263 296 on cardiometabolic parameters, fecal short-chain fatty acid (SCFA) contents biomarkers stress in colon heart tissues male rats fed an HFD. Male Wistar were grouped into control (CTL, n = 6), HFD (n 6) (HFD-Lf, groups. The L.fermentum (1 × 109 CFU/mL each strain) was...
The purpose of this study was to evaluate the antibacterial and antivirulence activities an essential oil from E. stipitata (EsEO) leaves against Staphylococcus aureus as well its mechanism action. determination activity based on MIC MBC. explored with growth curve, synergistic effect, cell membrane permeability assays. In addition, antimicrobial in a model S. aureus-infected Tenebrio mollitor larvae cytotoxicity fibroblasts macrophages were evaluated. MBC EsEO 128–512 μg/mL 256–1024 μg/mL,...
In this study, the toxicity and antinociceptive effects of ethanolic extract Croton blanchetianus leaves were investigated in mice. Phytochemical analysis was performed by thin layer chromatography (TLC) high–performance liquid (HPLC) revealed presence alkaloids, reducing sugars, cinnamic derivatives, flavonoids, saponins, condensed tannins, terpenes, steroids. Acute evaluated administration a single dose 2000 or 5000 mg/kg b.w. (per os i.p.). The (50, 100, 200 per os) for genotoxicity...