A5057239850- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- Insect Pest Control Strategies
- Phytochemicals and Antioxidant Activities
- Phytochemistry and Biological Activities
- Bee Products Chemical Analysis
- Natural product bioactivities and synthesis
- Agricultural and Food Sciences
- Botanical Research and Applications
- Ethnobotanical and Medicinal Plants Studies
- Psidium guajava Extracts and Applications
- Pomegranate: compositions and health benefits
- Phytochemical compounds biological activities
- Plant biochemistry and biosynthesis
- Phytochemistry and Bioactivity Studies
- Antifungal resistance and susceptibility
- Moringa oleifera research and applications
- Bioactive Natural Diterpenoids Research
- Insect Utilization and Effects
- Mosquito-borne diseases and control
- Natural Antidiabetic Agents Studies
- Mycorrhizal Fungi and Plant Interactions
- Fungal Biology and Applications
- Phytochemicals and Medicinal Plants
- Microencapsulation and Drying Processes
Universidade Federal de Pernambuco
2016-2025
Universidade Católica de Pernambuco
2024
Universidade Federal do Rio Grande do Norte
2010-2020
Universidade de Pernambuco
2017
Instituto de Ciências Farmacêuticas
2012-2015
Universidade Federal de Goiás
2013
Universidade Federal de Jataí
2013
The traditional use of Eugenia uniflora L. ("Pitanga") is reported due to several properties, which have often been related its flavonoid content.The aim was evaluate analytical procedures for quantification total flavonoids content (TFCs) by ultraviolet-visible (UV-Vis) spectrophotometry in the herbal material (HM), crude extract (CE), and fractions from leaves E. uniflora.The method after complexation with aluminum chloride (AlCl3) evaluated: amount sample (0.25-1.5 g); solvent (40%-80%...
This study showed phytochemical composition and evaluates the anti-inflammatory, analgesic activities of crude extract (CE) fractions from E. uniflora Linn leaves.Polyphenols present in (CE), aqueous fraction (AqF), ethyl acetate (EAF) treated leaves were shown by chromatographic analysis order to conduct a characterization. Antibacterial activity was evaluated based on minimum inhibitory concentrations (MICs) determined using agar dilution method. Doses 50, 100, 200 mg/kg CE applied for...
Acanthospermum hispidum DC., Asteraceae, is widely used in folk medicine Brazil to treat respiratory diseases; this biological property has been attributed its phytosterol content. This study evaluated the spectrophotometric assay method quantify total content raw materials and extracts from roots of A. hispidum. The procedure was based on quantification at 625 nm after Liebermann-Burchard reaction. for linearity, repeatability, intermediate precision, accuracy robustness. date indicated...
Morus alba L. (white mulberry) is used in traditional medicine worldwide, including Brazil. The leaves of this plant are to treat inflammatory disorders. Universal interest necessitates studies on the toxicological safety and scientific substantiation medicinal properties M. alba. In previous work, we investigated acute toxicity orally administered ethanol extract mice.This work was designed investigate obtained from for when intraperitoneally administered, vivo genotoxicity, potential...
Eugenia uniflora L., Myrtaceae, popularly known as "pitanga", is used in traditional medicine due the properties attributed to its chemical content, these being mainly hydrolysable tannins and flavonoids. This study provides a qualitative quantitative evaluation of profile from leaves E. uniflora. The HPLC analysis was carried out on C18 column (4.6 mm × 250 mm, 5 μm) by gradient elution with methanol water (acidified trifluoracetic acid); silica gel Plates 60-F 254 10–12 μm 5–6 particles,...
The stem bark and pods of "jucá" are widely used in Brazilian folk medicine and, despite their therapeutic relevancies, there insufficient reports about quality control. Both herbal drugs from the species rich tannins, which showed a lot biological economic interest. Thus, purpose this study was to evaluate method for quantification tannins L. ferrea. performance tested against influence most relevant parameters (reaction time; amount drug; type precipitationagents; concentration reagents)....
Abstract Plectranthus barbatus Andrews (Lamiaceae) is widely distributed in the world and has a range of popular therapeutic indications. This work aimed to evaluate phytochemical characterization two leaf extracts P. barbatus, their antimicrobial, antineoplastic immunomodulatory potential. After collection, herborization obtainment aqueous extract (PBA) acetone:water 7:3 organic (PBO), was performed by high-performance liquid chromatography (HPLC). The antimicrobial activity determine...
This study aimed to provide a comprehensive understanding of the acute and subacute safety phytochemical profile pomegranate leaves, aligning with growing interest in sustainable, plant‐based therapeutics. The composition, toxicity spray‐dried hydroethanolic extract from leaves (SDE) were investigated using experimental animal models. Utilizing UV‐visible spectrophotometry liquid chromatography‐mass spectrometry (LC‐MS), diverse array tannins flavonoids, totaling 38 compounds, was...
In the original publication [...]
The aim of this work was to find how medicinal plants play an important role as source new bioactive molecules. To evaluate the antifungal activity 10 from northeastern Brazil, traditionally used anti-infective agents. 30 crude extracts (water; ethanol:water, 1:1; acetone:water, 1:1) against four standard species Candida yeasts (Candida albicans ATCC 90028, dubliniensis 7289, glabrata 2001 and krusei 6258) investigated by Minimal Inhibitory Concentration (MIC), using microdilution method...
Trichophyton rubrum and mentagrophytes complex, or spp. are the main etiologic agents of dermatophytosis, whose treatment is limited by high cost antifungal treatments, their various side effects, emergence resistance amongst these species. This study evaluated in vitro antidermatophytic activity 23 crude extracts from nine plant species semiarid vegetation (caatinga) found Brazil. The were tested at concentrations ranging 1.95 to 1,000.0 mg/mL broth microdilution assay against reference...
This study evaluated the influence of extract Eugenia uniflora in adhesion to human buccal epithelial cells (HBEC) biofilm formation and cell surface hydrophobicity (CSH) Candida spp. isolated from oral cavity kidney transplant patients. To evaluate virulence attributes vitro, nine yeasts were grown presence absence 1000 μg/mL extract. Adhesion was quantified using number adhered 150 HBEC determined by optical microscope. Biofilm two methodologies: XTT...
Candida albicans is a diploid yeast that in some circumstances may cause oral or oropharyngeal infections. Yeasts virulence factors contribute for both the maintenance of colonizing strains addition to damage and tissue invasion, thus establishment infection occurs. The limited arsenal antifungal drugs treatment candidiasis turn investigation natural products mandatory discovery new targets drug development. Therefore, tropical countries emerge as important providers with potential...
The aim of this work was to evaluate the spectrophotometric methodology for determining total flavonoid content (TFC) in herbal drug and derived products from Bauhinia monandra Kurz. Several analytical parameters method grounded on complex formed between flavonoids AlCl 3 were evaluated such as amount (0.25 1.25 g); solvent composition (ethanol 40 80%, v/v); well reaction time concentration (2 9%, w/v). adjusted aqueous extractives its performance studied through precision, linearity...
Complexation with cyclodextrins (CDs) is a technique that has been extensively used to increase the aqueous solubility of oils and improve their stability. In addition, this convert into solid materials. This work aims develop inclusion complexes Copaifera multijuga oleoresin (CMO), which presents anti-inflammatory activity, β-cyclodextrin (β-CD) hydroxypropyl-β-cyclodextrin (HP-β-CD) by kneading (KND) slurry (SL) methods. Physicochemical characterization was performed verify occurrence...
Spondias tuberosa is a plant that produces fruit crop with high economic relevance at Brazilian Caatinga. Its roots and leaves are used in folk medicine.Chemical composition of hexane extract from S. was evaluated by thin-layer chromatography (TLC), high-performance liquid (HPLC) 1H nuclear magnetic resonance (NMR). Antioxidant potential investigated DPPH ABTS assays. Antifungal action on Candida species determining the minimal inhibitory concentration (MIC50) putative mechanisms were...