A5077031477- Pain Mechanisms and Treatments
- Pharmacological Effects of Natural Compounds
- Drug Solubulity and Delivery Systems
- Natural product bioactivities and synthesis
- Diagnosis and Treatment of Venous Diseases
- Crystallization and Solubility Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Public Health in Brazil
- Plant Toxicity and Pharmacological Properties
- Muscle metabolism and nutrition
- Healthcare and Venom Research
- Advanced Drug Delivery Systems
- Phytochemistry and Bioactive Compounds
- Pharmacology and Obesity Treatment
- 3D Printing in Biomedical Research
- Probiotics and Fermented Foods
- Lichen and fungal ecology
- Pressure Ulcer Prevention and Management
- Musculoskeletal pain and rehabilitation
- Bee Products Chemical Analysis
- Advancements in Transdermal Drug Delivery
- Drug-Induced Hepatotoxicity and Protection
- Essential Oils and Antimicrobial Activity
- Agricultural and Food Sciences
Universidade Federal de Sergipe
2016-2021
Chronic venous insufficiency is characterized by chronic reflux disorder of blood from the peripheral to central vein, with subsequent hypertension and resulting changes in skin. Traditionally, nonsurgical treatments relied on use compression therapy, more recently a variety flavonoids have been shown positive effects. There also developments effective drug delivery systems using various textiles nanotechnology provide new therapeutic options. Our objective was develop formulation containing...
Complexation with cyclodextrins (CDs) is a technique that has been extensively used to increase the aqueous solubility of oils and improve their stability. In addition, this convert into solid materials. This work aims develop inclusion complexes Copaifera multijuga oleoresin (CMO), which presents anti-inflammatory activity, β-cyclodextrin (β-CD) hydroxypropyl-β-cyclodextrin (HP-β-CD) by kneading (KND) slurry (SL) methods. Physicochemical characterization was performed verify occurrence...
Oral infections are associated with the appearance of systemic diseases. Among natural products, commercially used in dental formulations is thymol (TM). However, this compound presents low stability. In order to overcome these limitations, membranes were prepared using solvent evaporation method and TM/β-cyclodextrin liofilization technique. The results showed that presence inclusion complex causes considerable modifications physical-chemical, morphological, mucoadhesive properties....
Venous ulcers are a more severe complication of chronic venous insufficiency, significantly compromising patient quality life (QoL). Compressive stockings still the gold standard treatment method with alternative therapies currently being evaluated. In this perspective, we investigate influence compressive impregnated hesperetin-based nanocapsules in healing process ulcers. were applied to consenting for 6 months following all relevant ethical principles studies. The was evaluated at...
A Hipertensão Arterial Sistêmica (HAS) é uma condição clínica multifatorial caracterizada por níveis elevados e sustentados da pressão arterial. Um dos mecanismos para controle HAS meio do bloqueio receptores de angiotensina II (AII). losartana potássica (LP), exemplo clássico antagonistas subtipo AT1, um fármacos mais utilizados o tratamento HAS. As formulações obtidas em farmácias magistrais devem apresentar qualidade suficiente garantir a eficácia segurança paciente. Diante exposto,...
A segurança e eficácia de medicamentos produzidos em farmácias magistrais estão relacionadas diretamente com a uniformidade das doses unitárias. O gral o saco plástico são métodos bastante utilizados para garantir homogeneização pós na produção cápsulas, contudo, não há estudos relacionados padronização do tempo homogeneização. Diante disso, presente estudo teve como objetivo padronizar cápsulas paracetamol, fármaco este atualmente prescrito grande frequência. paracetamol seus excipientes...