A5087888185- Essential Oils and Antimicrobial Activity
- Medicinal Plant Extracts Effects
- Bee Products Chemical Analysis
- Pharmacological Effects of Natural Compounds
- Drug Solubulity and Delivery Systems
- Moringa oleifera research and applications
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Drug-Induced Hepatotoxicity and Protection
- Memory and Neural Mechanisms
- Ultrasound and Hyperthermia Applications
- Public Health in Brazil
- Seed and Plant Biochemistry
- Nanoparticles: synthesis and applications
- Analytical Chemistry and Chromatography
- Aquaculture disease management and microbiota
- Zebrafish Biomedical Research Applications
- Medicinal Plants and Neuroprotection
- Skin Protection and Aging
- Inflammatory Bowel Disease
- Chemistry Education and Research
- Nanoparticle-Based Drug Delivery
- Hydrogen's biological and therapeutic effects
Universidade Federal de Sergipe
2015-2021
Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Sul
2019
Propolis is a bee product widely used in folk medicine due to its numerous pharmacological properties. However, samples from different regions can differ chemical composition, effectiveness, and side effects. Despite the widespread use of Brazilian red propolis, which an isoflavone-rich variety, toxicity has not been carefully studied.To assess acute sub-acute hydroethanolic extract propolis (HERP) administered orally rats.HERP for (300mg/kg) (10, 100 200mg/kg) studies was rats according...
The diabetic key enzymes inhibition, nutritional, antioxidant activity and bioactive compounds identification of Passiflora subpeltata fruit pulp were investigated. Fifteen polyphenolic including protocatechuic acid, ferulic vanillic epicatechin, p-coumaric cinnamic eriodictyol quercetin-3-glucoside identified in the this species by using UHPLC-QqQ-MS/MS analysis. total carbohydrates crude protein contents 2.62 mg glucose equivalent/g sample 8.80 BSA pulp, respectively. fresh P. contained...
Polyphenolics (flavonoid and phenolic) rich plants are the effective source for treatment of acute chronic degenerative diseases including inflammatory bowel disease. This study was aimed to examine effects polyphenolics leaf acetone extract P. subpeltata against indomethacin induced ulcerative colitis in rats. Two consecutive days administration produced inflammation GIT tissues Further, plant 200 400 mg/kg were continued until 11th day. Then hematological, enzymatic antioxidants, MPO...
Twenty-four phenolic compounds including daidzein, epicatechin and artepillin C were identified in Passiflora leschenaultii DC. fruit by UHPLC-QqQ-MS/MS analysis. The aroma profile has been studied using the HS–SPME/GC–MS which revealed 67 volatile 13 terpenes, 18 alcoholics, 15 esters, ketones acids. Further, proximate composition, anti-radical anti-diabetic activities of pulp also determined. fresh P. registered higher total (691.90 mg GAE/g extract) tannin (313.81 contents it exhibited...
Passion fruit (Passiflora leschenaultii DC), an endemic species to peninsular India, is traditionally used treat various ailments such as dysentery, urinary stone disease and wounds. The present study aimed investigate the antioxidant, analgesic, anti-inflammatory, antipyretic activities chemical composition of leaf extracts P. leschenaultii. Bioactive secondary metabolites total phenolics, tannins flavonoids were quantified. Antioxidant determined by DPPH, ABTS+, FRAP, metal chelating...
Anxiety disorders appear to involve distinct neurobiological mechanisms and several medications are available against this mental health problem. However, pharmacological therapeutic approaches display undesirable side effects for patients, particularly when long-term therapy is required. Some evidences have suggested that Coriandrum sativum extract (CSE) provide sedative anxiolytic effects. We investigate if CSE could attenuate anxiety-like behaviors induced by novelty alarm substance...
Abstract Background and objective This study aimed to assess the effectiveness of treatment with alpha‐terpineol (αTPN) complexed beta‐cyclodextrin (βCD) on oral, blood, hepatic parameters in ligature‐induced periodontitis. Material Methods Forty female rats were distributed among following groups: control (vehicle solution), periodontitis (ligature + vehicle 5 mg/kg αTPN‐βCD (ligature), 25 (ligature). Compounds administered daily via intraperitoneal injection over a 20‐day period....
A gel containing the inclusion complex of quercetin and β-cyclodextrin was developed in order to verify its effects, isolated or using phonophoresis, on oxidative biomarkers after skeletal muscle injury. 30 male rats were divided into one five groups: Control (CTRL), Muscle Injury (MI), Therapeutic Pulsed Ultrasound (TPU), plus Quercetin (TPU gel-QUE) (QUE). complexed with β-Cyclodextrin (β-CD) chromatography (HPLC). TPU application occurred 2, 12, 24, 48, 72, 96 hours intervals...
Multiresistant bacteria represent a global health problem, encouraging the development of effective antimicrobial treatments. In this context, metallic nanoparticles like silver (AgNPs) can serve as an alternative to pathogenic bacterial growth control since AgNPs have minimal risk promoting resistance. The chemical methods synthesize involves toxic agents however, way obtain them would be employing plant extract due its redox ability. current study, Spondias tuberosa hydroethanolic leaf (...
O controle da qualidade de sólidos por meio ensaios físico-químicos apresenta grande importância na garantia medicamentos. Diante disto, este estudo teve como objetivo comparar a comprimidos nimesulida com β-ciclodextrina (Maxsulid®) e sem (Nisulid®) forma investigar se os testes vigentes aplicam às formas farmacêuticas que contenham complexos inclusão ciclodextrinas em sua composição. Para tal, foram realizados descritos Farmacopeia Brasileira 6ª edição para nimesulida. Frente ao exposto,...