A5055807719- Essential Oils and Antimicrobial Activity
- Venomous Animal Envenomation and Studies
- Exercise and Physiological Responses
- Pain Mechanisms and Treatments
- Cardiac Ischemia and Reperfusion
- Asthma and respiratory diseases
- Bee Products Chemical Analysis
- Neuropeptides and Animal Physiology
- Phytochemistry Medicinal Plant Applications
- Adipose Tissue and Metabolism
- Pancreatitis Pathology and Treatment
- Healthcare and Venom Research
- Apelin-related biomedical research
- Reproductive System and Pregnancy
- Fatty Acid Research and Health
- Marine Invertebrate Physiology and Ecology
- Natural product bioactivities and synthesis
- Laser Applications in Dentistry and Medicine
- Phytochemicals and Antioxidant Activities
- Ion channel regulation and function
- Antimicrobial Peptides and Activities
- Natural Antidiabetic Agents Studies
- Biological Stains and Phytochemicals
- Moringa oleifera research and applications
- Wound Healing and Treatments
Universidade Federal de Sergipe
2016-2025
Antea Group (France)
2024
Frontier Science Foundation-Hellas
2024
Long Island University
2024
Alpha Omega Electromagnetics (United States)
2024
Institute of Electrical and Electronics Engineers
2024
Atlantic Industries (Canada)
2024
Cedar Rapids Public Library
2024
Chapter Arts Centre
2024
Gillette Children's Specialty Healthcare
2024
Background and purpose: Recent findings suggest that the noxious gas H 2 S is produced endogenously, physiological concentrations of are able to modulate pain inflammation in rodents. This study was undertaken evaluate ability endogenous exogenous carrageenan‐induced synovitis rat knee. Experimental approach: Synovitis induced Wistar rats by intra‐articular injection carrageenan into knee joint. Sixty minutes prior injection, were pretreated with indomethacin, an inhibitor formation ( dl...
(1) Background: Species of the genus Cymbopogon and its essential oil are known for their antioxidant hypoglycemic effects. This study aimed to investigate impact flexuosus (EOCF), major component, citral, on glycemic, lipid, parameters, oxidative stress in a type 1 diabetes (DM1) rat model. (2) Methods: Initially, EOCF was analyzed by Gas chromatography-mass spectrometry (GC-MS) activity citral evaluated. Next, male Wistar rats (3 months old, 200–250 g) induced with DM1 using Streptozotocin...
Validate a model of high-fat diet-induced obesity, low cost, easy reproducibility, that could express characteristics observed in human, and would enable subsequent therapy proposals.Sixteen Swiss mice received standard diet (DP) or (DH) for 10 weeks.Although the DP group had greater water (p < 0.01) feed 0.001) consumption, DH body weight 0.5) adipose tissue gain 0.001), favoring higher adiposity index glucose 0.01), area under curve insulin tolerance tests.A obesity has been validated,...
Rose-oxide is a fragrance found in roses and rose oil. There are no reports about the pharmacological activity of this molecule. The present study was undertaken to evaluate whether rose-oxide (RO) has anti-inflammatory properties investigate possible mechanisms involved with its effects. RO first suggested by formalin test mice, an inflammatory pain model, because intraperitoneal (i.p.) administration (50 100mg/kg) inhibited only late phase test. To further RO, complete Freund's adjuvant...
No specific therapeutics are available for the treatment of sepsis-induced liver dysfunction, a clinical complication strongly associated with high mortality rate septic patients. This study investigated effect essential oil Hyptis crenata (EOHc), lamiaceae plant used to treat disturbances in Brazilian folk medicine, on function during early sepsis. Sepsis was induced by cecal ligation and puncture (CLP) model. Rats were divided into four groups: Sham, Sham+EOHc, CLP, CLP+EOHc. EOHc (300...
Flavanone derivatives utilize the fundamental flavanone framework to enhance and target distinct bioactivities, rendering them valuable precursors in synthesis development of pharmaceuticals. Here we explore enzyme-catalyzed intramolecular C(sp3)-H...
Physical exercise reduces the deleterious effects of cardiovascular and inflammatory disorders. The purpose present study was to evaluate beneficial physical training on responses following lung ischaemia–reperfusion (IR) in rats. Male Wistar rats were divided into sham-operated animals sedentary trained submitted IR. run programme consisted 5 sessions·week<sup>−1</sup>, each lasting 60 min·day<sup>−1</sup>, at 66% maximal oxygen consumption for 8 weeks. left pulmonary artery, bronchus vein...
Caesalpinia pyramidalis Tul., Fabaceae, is a plant with an anti-inflammatory activity that used in folk medicine. To evaluate the mechanism of action this plant, studies were performed on its antinociceptive and properties using ethanol extract (EE) made from inner bark. Oral treatment mice EE (100, 200, 400 mg/kg) decreased their acetic acid-induced abdominal writhes (p<0.001) formalin-induced paw licking both first second phases (p<0.001). This increased reaction time hot-plate test (400...
Caesalpinia pyramidalis Tul. (Fabaceae) is a plant found in the Northeast of Brazil that popularly used to treat inflammation. Acute pancreatitis (AP) an inflammatory disease for which abdominal pain relevant symptom. As there no specific therapy AP, we investigated effect ethanol extract from inner bark C. (EECp) on AP induced by common bile duct obstruction (CBDO) rats.AP was male Wistar rats (200-250 g, n=6-8) through laparotomy and subsequent CBDO. Animals were euthanized after 6 (G6h)...
Citronellal is a monoterpene present in the oil of many species, including Cymbopogon winterianus Jowitt (Poaceae).The study investigated effect citronellal on inflammatory nociception induced by different stimuli and examined involvement NO-cGMP-ATP-sensitive K⁺ channel pathway.We used male Swiss mice (n = 6 per group) that were treated intraperitoneally with (25, 50 or 100 mg/kg) 0.5 h after subplantar injection 20 μl carrageenan (CG; 300 µg/paw), tumor necrosis factor-α (TNF-α; pg/paw),...
Introduction: Acute pancreatitis (AP) may be severe and cause hospitalization or death, the available treatment is insufficient to control pancreatic inflammation pain. Rutin a natural flavonoid with potential treat AP via anti-inflammatory, antinociceptive, antioxidant activities.Aim: This study investigated beneficial effects of rutin on experimental induced by l-arginine administration in mice.Methods: The l-arginine-induced model was used Swiss mice (n = 6–8). Mice submitted induction...