Nataly Diniz de Lima Santos

ORCID: 0000-0001-9155-6773
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Research Areas
  • Insect Pest Control Strategies
  • Moringa oleifera research and applications
  • Insect Resistance and Genetics
  • Mosquito-borne diseases and control
  • Insect Utilization and Effects
  • Essential Oils and Antimicrobial Activity
  • Agricultural pest management studies
  • Studies on Chitinases and Chitosanases
  • Transgenic Plants and Applications
  • Ginger and Zingiberaceae research
  • Insect and Pesticide Research
  • Antimicrobial Peptides and Activities
  • Insect and Arachnid Ecology and Behavior
  • Antifungal resistance and susceptibility
  • Dermatology and Skin Diseases
  • Biochemical and Structural Characterization
  • Nail Diseases and Treatments
  • Glycosylation and Glycoproteins Research
  • Ethnobotanical and Medicinal Plants Studies
  • Plant Pathogenic Bacteria Studies
  • Plant Parasitism and Resistance
  • Environmental Sustainability and Education
  • Insect symbiosis and bacterial influences
  • Iron Metabolism and Disorders
  • Antibiotic Resistance in Bacteria

Universidade Federal de Pernambuco
2012-2025

Universidade Federal Rural de Pernambuco
2023-2025

Centro Universitário da Cidade
2013

Aedes aegypti larvae have developed tolerance to many insecticides used for mosquito control. Moringa oleifera seeds contain a water-soluble lectin (WSMoL) and this paper reports the effect of M. seed extracts (MoE(1-15)) WSMoL on development survival A. larvae. peptide from in-gel trypsin digestion is also described. MoE(1-15) showed hemagglutinating activity had similarity with flocculating proteins seeds. MoE(1) MoE(3) delayed larval which stopped in third instar (L3) MoE(6) MoE(15)....

10.1016/j.chemosphere.2009.08.022 article EN publisher-specific-oa Chemosphere 2009-09-11

Natural insecticides against the vector mosquito Aedes aegypti have been object of research due to their high level eco-safety. The water-soluble Moringa oleifera lectin (WSMoL) is a larvicidal agent A. aegypti. This work reports effects WSMoL on oviposition and egg hatching aegypti.WSMoL crude preparations (seed extract 0-60 protein fraction), at 0.1 mg/mL concentration, did not affect oviposition, while gravid females laid eggs preferentially (73%) in vessels containing isolated (0.1...

10.1371/journal.pone.0044840 article EN cc-by PLoS ONE 2012-09-06

The Alpinia purpurata inflorescence contains a lectin (ApuL), which has immunomodulatory activities on human cells. In the present work, it was evaluated antibacterial and antifungal effects of ApuL against pathogens. showed bacteriostatic activity non-resistant (UFPEDA-02) an oxacillin-resistant isolate (UFPEDA-672) Staphylococcus aureus with minimal inhibitory concentrations (MIC50) 50 400 μg/mL, respectively. addition, bactericidal effect (minimal concentration: 200 μg/mL). For Candida...

10.1016/j.micpath.2018.08.027 article EN publisher-specific-oa Microbial Pathogenesis 2018-08-22

The lesser mealworm, Alphitobius diaperinus, is a widespread pest in poultry farming, causing economic losses and facilitating the spread of pathogens. Current control methods rely heavily on synthetic insecticides, which raise environmental concerns contribute to resistance. This study investigated insecticidal potential Moringa oleifera seed preparations, including an aqueous extract (AE), protein-enriched fraction (PF), isolated lectin (WSMoL), against A. diaperinus. Contact assays...

10.3390/plants14040511 article EN cc-by Plants 2025-02-07

Spondias tuberosa is a plant that produces fruit crop with high economic relevance at Brazilian Caatinga. Its roots and leaves are used in folk medicine.Chemical composition of hexane extract from S. was evaluated by thin-layer chromatography (TLC), high-performance liquid (HPLC) 1H nuclear magnetic resonance (NMR). Antioxidant potential investigated DPPH ABTS assays. Antifungal action on Candida species determining the minimal inhibitory concentration (MIC50) putative mechanisms were...

10.1186/s12906-018-2350-2 article EN cc-by BMC Complementary and Alternative Medicine 2018-10-19

Moringa oleifera seed cake, which is the coproduct of oil extraction, may be a source lectin. This study reports purification lectin from M. cake (WSMoLC) and determination its effect on larvae, eggs oviposition Aedes aegypti. WSMoLC was isolated (purification fold: 3573) by treatment water extract with ammonium sulphate (60%) chromatography lectin-rich fraction chitin column. In gel trypsin, digestion followed mass spectrometry revealed similarity peptides other proteins. exerted...

10.1016/j.procbio.2016.06.026 article EN publisher-specific-oa Process Biochemistry 2016-06-29

The water-soluble Moringa oleifera lectin (WSMoL) exhibits larvicidal, ovicidal, and oviposition-stimulant effects on Aedes aegypti. Here, we evaluated the influence of gamma irradiation activity WSMoL against A. Irradiation with 10 mGy Gy did not result in loss protein molecules; however, irradiated samples presented a distinct profile gel filtration chromatography. Bis-ANS probe fluorescence was similar when incubated non-irradiated mGy-irradiated samples, but less intense observed...

10.1016/j.sajb.2018.05.001 article EN cc-by South African Journal of Botany 2018-05-18

Abstract Our objectives were to identify genes of the multi-drug efflux system and evaluate antimicrobial activities polypyrrole nanoparticles (PPy-NPs) aqueous extract Moringa oleifera against Staphylococcus spp. isolated from dairy farms in Northeast Brazil. Initially, 162 isolates subjected vitro sensitivity tests. Of these, 35 presented resistance phenotypes. These then referred for detection norA, norB, norC, msrA, mgrA, tet-38, lmrS genes, all which feature systems. In carrying minimum...

10.1017/s0022029920000874 article EN Journal of Dairy Research 2020-08-01

This work aimed to purify, characterize, and evaluate the immunomodulatory activity of a lectin from Aesculus hippocastanum seeds (AhSL). The was isolated saline extract through chromatography on DEAE-Sephadex column. Protein homogeneity subunit composition were evaluated with polyacrylamide gel electrophoresis (PAGE) under native denaturing (SDS-PAGE) conditions, respectively. AhSL for trypsin inhibitor activity, carbohydrate-binding specificity, effects cations (Ca2+, Mn2+, Mg2+),...

10.1016/j.crbiot.2022.03.003 article EN cc-by-nc-nd Current Research in Biotechnology 2022-01-01

The mosquito Aedes aegypti L. is a vector transmitting diseases such as dengue, chikungunya and Zika virus fever. water-soluble lectin from Moringa oleifera Lam. seeds (WSMoL) larvicidal, ovicidal can stimulate oviposition in A. aegypti. This study aimed to investigate whether WSMoL could bind membrane proteins legs. Initially, the legs were extracted using sodium deoxycholate, digitonin, dodecyl sulfate (SDS) or Triton X-100. protein concentration was found be higher extract obtained X-100,...

10.1016/j.ijbiomac.2020.06.189 article EN publisher-specific-oa International Journal of Biological Macromolecules 2020-06-23
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