A5069365973- Traditional Chinese Medicine Analysis
- Cosmology and Gravitation Theories
- Galaxies: Formation, Evolution, Phenomena
- Pharmacological Effects of Natural Compounds
- Chromatography in Natural Products
- Dark Matter and Cosmic Phenomena
- Natural product bioactivities and synthesis
- Online Learning and Analytics
- Radio Astronomy Observations and Technology
- Flavonoids in Medical Research
- Fluorine in Organic Chemistry
- Intelligent Tutoring Systems and Adaptive Learning
- Gut microbiota and health
- Sulfur-Based Synthesis Techniques
- Traditional Chinese Medicine Studies
- Metabolomics and Mass Spectrometry Studies
- Astronomy and Astrophysical Research
- Diet and metabolism studies
- Astrophysics and Cosmic Phenomena
- Ginseng Biological Effects and Applications
- Muscle metabolism and nutrition
- Phytochemistry and biological activity of medicinal plants
- Solar and Space Plasma Dynamics
- Phytochemistry and Bioactive Compounds
- Clinical Nutrition and Gastroenterology
Dali University
2022-2025
University of Southern California
2022-2025
Huazhong University of Science and Technology
2020-2025
Southern California University for Professional Studies
2024-2025
Union Hospital
2025
Bengbu Medical College
2024
Shanghai University of Traditional Chinese Medicine
2014-2024
Northwestern Polytechnical University
2021-2024
China Electronics Technology Group Corporation
2024
Beijing Sport University
2021-2024
Abstract Enantioselective trifluoromethylthiolation, especially of alkenes, is a challenging task. In this work, we have developed an efficient approach for enantioselective trifluoromethylthiolating lactonization by designing indane‐based bifunctional chiral sulfide catalyst and shelf‐stable electrophilic SCF 3 reagent. The desired products were formed with diastereoselectivities >99:1 good to excellent enantioselectivities. transformation represents the first trifluoromethylthiolation...
We present cosmological constraints from a gravitational lensing mass map covering 9400 sq. deg. reconstructed CMB measurements made by the Atacama Cosmology Telescope (ACT) 2017 to 2021. In combination with BAO (from SDSS and 6dF), we obtain amplitude of matter fluctuations $\sigma_8 = 0.819 \pm 0.015$ at 1.8% precision, $S_8\equiv\sigma_8({\Omega_{\rm m}}/0.3)^{0.5}=0.840\pm0.028$ Hubble constant $H_0= (68.3 1.1)\, \text{km}\,\text{s}^{-1}\,\text{Mpc}^{-1}$ 1.6% precision. A joint...
We present new measurements of cosmic microwave background (CMB) lensing over $9400$ sq. deg. the sky. These are derived from Atacama Cosmology Telescope (ACT) Data Release 6 (DR6) CMB dataset, which consists five seasons ACT temperature and polarization observations. determine amplitude power spectrum at $2.3\%$ precision ($43\sigma$ significance) using a novel pipeline that minimizes sensitivity to foregrounds noise properties. To ensure our results robust, we analyze an extensive set null...
Observations of the millimeter sky contain valuable information on a number signals, including blackbody cosmic microwave background (CMB), Galactic emissions, and Compton-y distortion due to thermal Sunyaev-Zel'dovich (tSZ) effect. Extracting new insight into cosmological astrophysical questions often requires combining multiwavelength observations spectrally isolate one component. In this work, we present arc-minute-resolution map, which traces out line-of-sight-integrated electron...
Student performance prediction (SPP) aims to evaluate the grade that a student will reach before enrolling in course or taking an exam. This problem is kernel task toward personalized education and has attracted increasing attention field of artificial intelligence educational data mining (EDM). paper provides systematic review SPP study from perspective machine learning mining. partitions into five stages, i.e., collection, formalization, model, prediction, application. To have intuition on...
We explore a self-interacting neutrino cosmology in which neutrinos experience delayed onset of free-streaming. use the effective field theory large-scale structure (LSS) to model matter distribution on mildly nonlinear scales within for first time. perform combined likelihood analysis BOSS full-shape galaxy clustering, weak lensing, and Lyman-$\ensuremath{\alpha}$ forest measurements, together with cosmic microwave background (CMB) data from Planck. find that full dataset strongly favors...
Cross-correlation between weak lensing of the Cosmic Microwave Background (CMB) and galaxies offers a way to place robust constraints on cosmological astrophysical parameters with reduced sensitivity certain systematic effects affecting individual surveys. We measure angular cross-power spectrum Atacama Cosmology Telescope (ACT) DR4 CMB galaxy measured by Dark Energy Survey (DES) Y3 data. Our baseline analysis uses convergence map derived from ACT-DR4 $\textit{Planck}$ data, where most...
Natural products have always been important resources either as therapeutic agents or lead compounds for the production of pharmaceutical compounds. Osthole, 7-methoxy-8-(3-methyl-2-butenyl) coumarin, an ingredient a Traditional Chinese Medicine(TCM), has received considerable attention recently because its significant and diverse pharmacological activities, including anticancer, antisteoporotic, antiproliferative, which make it very promising natural compound new drug discovery. The present...
We constrain interacting dark matter and energy (IDMDE) models using a 450-degree-square cosmic shear data from the Kilo Degree Survey (KiDS) angular power spectra Planck's latest microwave background measurements. revisit discordance problem in standard Lambda cold ($\Lambda$CDM) model between weak lensing Planck datasets extend discussion by introducing sectors. The IDMDE are found to be able alleviate KiDS as previously inferred $\Lambda$CDM model, moderately favored combination of two datasets.
Predicting and understanding student learning performance has been a long-standing task in science, which can benefit personalized teaching learning. This study shows that the progress towards this be accelerated by using record data to feed deep model considers intrinsic course association structured features. We proposed multi-source sparse attention convolutional neural network (MsaCNN) predict grades general formulation. MsaCNN adopts multi-scale convolution kernels on grade records...
Ban‐Xia‐Xie‐Xin‐Tang (BXXXT) is a classical formula from Shang‐Han‐Lun which one of the earliest books TCM clinical practice. In this work, we investigated therapeutic mechanisms BXXXT for treatment multiple diseases using network pharmacology approach. Here three representative (colitis, diabetes mellitus, and gastric cancer) were discussed, focus on in silico methods that integrate drug‐likeness screening, target prioritizing, multilayer extending. A total 140 core targets 72 compounds...
Chronic atrophic gastritis (CAG) is characterized by the loss of gastric glandular cells, which are replaced intestinal-type epithelium and fibrous tissue. Ginsenoside Rg1 (Rg1) prevalent ginsenoside in ginseng, with a variety biological activities, usually added to functional foods. As novel form programmed cell death (PCD), pyroptosis has received substantial attention recent years. Despite numerous beneficial effects, curative impact on CAG whether its putative mechanism partially via...
Abstract Enantioselective trifluoromethylthiolation, especially of alkenes, is a challenging task. In this work, we have developed an efficient approach for enantioselective trifluoromethylthiolating lactonization by designing indane‐based bifunctional chiral sulfide catalyst and shelf‐stable electrophilic SCF 3 reagent. The desired products were formed with diastereoselectivities >99:1 good to excellent enantioselectivities. transformation represents the first trifluoromethylthiolation...
If a fraction $f_{\rm dcdm}$ of the Dark Matter decays into invisible and massless particles (so-called "dark radiation") with decay rate (or inverse lifetime) $\Gamma_{\rm dcdm}$, such will leave distinctive imprints on cosmological observables. With full consideration Boltzmann hierarchy, we calculate decay-induced impacts not only CMB but also redshift distortion kinetic Sunyaev-Zel'dovich effect, while providing detailed physical interpretations based evaluating evolution gravitational...
The interacting dark energy (IDE) model, which considers the interaction between and matter, provides a natural mechanism to alleviate coincidence problem can also relieve observational tensions under $\Lambda$CDM model. Previous studies have put constraints on IDE models by observations of cosmic expansion history, microwave background large-scale structures. However, these data are not yet enough distinguish from effectively. Because non-linear structure formation contains rich...
Spatial variations in the cosmic electron density after reionization generate microwave background anisotropies via Thomson scattering, a process known as ``patchy screening" effect. In this paper, we propose new estimator for patchy screening effect that is designed to mitigate biases from dominant foreground signals. We use it measure cross-correlation between \textit{unWISE} galaxies and screening, latter measured by Atacama Cosmology Telescope \textit{Planck} satellite. report first...
Purpose The purpose of this study was to observe the effects metformin on human esophageal cancer cell and investigate its possible mechanisms. Materials Methods Cell viability detected by using a Counting Kit-8, while cycle apoptosis were assessed flow cytometry western blot used measure expression related proteins. RNAi knockout pyruvate kinase muscle isozyme 2 (PKM2). An Eca109 tumor model established evaluate antitumor effect in vivo. Immunohistochemistry determined based PKM2 Bim...