A5044299256- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Fish Biology and Ecology Studies
- Identification and Quantification in Food
- Fish Ecology and Management Studies
- Aquaculture disease management and microbiota
- Cancer-related molecular mechanisms research
- Advanced biosensing and bioanalysis techniques
- Mesenchymal stem cell research
- Epigenetics and DNA Methylation
- Advanced Nanomaterials in Catalysis
- Planetary Science and Exploration
- Environmental and Biological Research in Conflict Zones
- Plant and Fungal Species Descriptions
- Ecology and biodiversity studies
- Spaceflight effects on biology
- Protein Kinase Regulation and GTPase Signaling
- Genetic Syndromes and Imprinting
- Caveolin-1 and cellular processes
- Heat shock proteins research
- Physiological and biochemical adaptations
- Platelet Disorders and Treatments
- Pancreatic function and diabetes
- Kruppel-like factors research
- Nanoparticles: synthesis and applications
Chongqing University
2022
Army Medical University
2019-2022
Sichuan University
2012-2020
Xinqiao Hospital
2019
Background: Irradiation disrupts the vascular niche where hematopoietic stem cells (HSCs) reside, causing delayed reconstruction.The subsequent recovery of sinusoidal vessels is key to regeneration and a prerequisite for reconstruction.We hypothesize that resident bone marrow macrophages (BM-Mφs) are responsible repairing HSC upon irradiation injury.Methods: We examined survival activation BM-Mφs in C57BL/6 mice total body irradiation.After BM-Mφ depletion via injected clodronate-containing...
Irradiation can greatly inhibit osteogenesis of bone marrow mesenchymal stem cells (BM-MSCs).However, the mechanism remains unclear.Methods: We analyzed expression profile long noncoding RNAs (lncRNAs) in BM-MSCs using microarray data.LncRNA TUG1 (Taurine Upregulated Gene 1) was selected and tested radiated non-radiated BM-MSCs.Functional analyses (in vitro) were performed to confirm role osteogenic inhibition induced by irradiation.A RIP (RNA immunoprecipitation) assay detect interaction...
The complete mitochondrial genome of the stone loach Triplophysa stoliczkae is 16,571 bp in size, consisting 13 protein-coding genes, 22 transfer RNA (tRNA) two ribosomal (rRNA) and a noncoding control region. As other vertebrates, most genes are encoded on heavy strand, except for nd6 eight tRNA which light strand. overall base composition strand T. A: 28.1%, T: 29.0%, C: 25.0%, G: 17.9%. alignment species regions exhibited high genetic variability rich A+T content.
The complete mitochondrial genome of the Triplophysa robusta has been determined in this study. It is 16,572 bp size and consists 13 protein-coding genes, 22 tRNA two rRNA one non-coding control region (D-loop). overall base composition heavy strand T. was A: 28.20%, T: 28.27%, C: 25.37%, G: 18.16%. total length genes 11,428 bp. Analysis indicated high genetic variability among species.
The complete mitochondrial genome of the stone loach Triplophysa bleekeri collected from Anning River, a tributary Yalong in Sichuan Province was sequenced. is 16,573 bp length, consisting 13 protein-coding genes, 22 transfer RNA (tRNA) two ribosomal (rRNA) and noncoding control region. Most genes are encoded on heavy strand, except for ND6 eight tRNAs. overall base composition T. 28.1% A, 28.4% T, 25.5% C, 18.0% G, with slight A+T bias 56.5%. genetic variability high among different species...
Megakaryocytes (MKs) are the unique non-pathological cells that undergo polyploidization in mammals. The polyploid formation is critical for understanding MK biology, and transcriptional regulation involved differentiation maturation of MKs. However, little known about functions elongation factors polyploidization. In this study, we investigated role transcription factor EloA polyploidy during differentiation. We found was highly expressed erythroleukemia cell lines HEL K562. Knockdown line...
The complete mitochondrial DNA genome of Ptychobarbus kaznakovi was sequenced and characterized. is 16,842 bp in length. Similar with most teleosts, it has two ribosomal RNA (rRNA) genes, 13 protein-coding 22 transfer (tRNA) one displacement loop (D-loop) region. Conserved sequence blocks, including ETAS, CSB-B, D, E, F, CSB1-3, were identified the D-loop, which similar to other species Cypriniformes. Nevertheless, a 55 tandem repeat array also at 3' end first finding Schizothoracinae....
Bone marrow mesenchymal stem cells (BM-MSCs) are multipotent with the capacity for self-renewal and differentiating into multiple cell types. However, underlying regulatory mechanism has not been fully clarified. Krüppel-like factors 9 (KLF9), a potential key transcription factor relevant to numerous physiological processes, detected during BM-MSCs adipogenic differentiation by bioinformatics (integrated) analyses from four different datasets. Our results indicated that KLF9 could regulate...