A5038709085- Marine Ecology and Invasive Species
- Developmental Biology and Gene Regulation
- Planarian Biology and Electrostimulation
- Aquatic Invertebrate Ecology and Behavior
- Marine Invertebrate Physiology and Ecology
- Marine Biology and Environmental Chemistry
- Marine Bivalve and Aquaculture Studies
- Neurobiology and Insect Physiology Research
- Genetics and Physical Performance
- Plant and Biological Electrophysiology Studies
- Marine Biology and Ecology Research
- Environmental DNA in Biodiversity Studies
- Insect Utilization and Effects
- Protist diversity and phylogeny
- 3D Printing in Biomedical Research
- Single-cell and spatial transcriptomics
- Physiological and biochemical adaptations
- Ocean Acidification Effects and Responses
- Morphological variations and asymmetry
- Insect and Arachnid Ecology and Behavior
Oxford Brookes University
2023-2025
University of Exeter
2024-2025
University of Vienna
2018-2022
University of Göttingen
2020
Many annelids can regenerate missing body parts or reproduce asexually, generating all cell types in adult stages. However, the putative stem populations involved these processes, and diversity of generated by them, are still unknown. To address this, we recover 75,218 single transcriptomes highly regenerative asexually-reproducing annelid Pristina leidyi. Our results uncover a rich type including specific as well novel types. Moreover, characterise transcription factors gene networks that...
Abstract Coloniality is a widespread growth form in cnidarians, tunicates, and bryozoans, among others. Colonies function as single physiological units despite their modular structure of zooids supporting tissues. A key question how structurally functionally distinct colony parts are generated. In the cnidarian Hydractinia symbiolongicarpus , colonies consist (polyps) interconnected by stolons attached to substrate. Using single-cell transcriptomics, we profiled ~200,000 cells, including two...
Abstract Annelids are a broadly distributed, highly diverse, economically and environmentally important group of animals. Most species can regenerate missing body parts, many able to reproduce asexually. Therefore, annelids generate all adult cell types in stages. However, the putative stem populations involved these processes, as well diversity generated by them, still unknown. Here, we recover 75,218 single transcriptomes Pristina leidyi , regenerative asexually-reproducing freshwater...
Allometry explores the relationship between an organism’s body size and its various components, offering insights into ecology, physiology, metabolism, disease. The cell is basic unit of biological systems, yet study cell-type allometry remains relatively unexplored. Single-cell RNA sequencing (scRNA-seq) provides a promising tool for investigating allometry. Planarians, capable growing degrowing following allometric scaling rules, serve as excellent model these studies. We used scRNA-seq to...
Ciliated trochophore-type larvae are widespread among protostome animals with spiral cleavage. The respective phyla often united into the superclade Spiralia or Lophotrochozoa that includes, for example, mollusks, annelids, and platyhelminths. Mollusks (bivalves, gastropods, cephalopods, polyplacophorans, their kin) in particular known morphological innovations lineage-specific plasticity of homologous characters (e.g., radula, shell, foot, neuromuscular systems), raising questions...
Abstract Coloniality is a widespread growth form in cnidarians, tunicates, and bryozoans, among others. Despite being modular, composed of multiple zooids supporting tissues, colonies function as single physiological unit. A major question the biology cellular mechanism generating structurally functionally distinct colony parts. The cnidarian Hydractinia establishes with different types (polyps), interconnected by gastrovascular system that attached to substrate known stolons. We obtained...
Revealing the mechanisms underlying breathtaking morphological diversity observed in nature is a major challenge Biology. It has been established that recurrent mutations hotspot genes cause repeated evolution of traits, such as body pigmentation or gain and loss structures. To date, however, it remains elusive whether contribute to natural variation size shape organs. As head morphology pervasive Drosophila, we studied molecular developmental basis differences compound eye two closely...
Mollusks are known for their highly diverse repertoire of body plans that often includes external armor in form mineralized hardparts. Representatives the Conchifera, one two major lineages comprises taxa which originated from a uni-shelled ancestor (Monoplacophora, Gastropoda, Cephalopoda, Scaphopoda, Bivalvia), particularly relevant regarding evolution mollusk shells. Previous studies have found shell matrix adult (teleoconch) is rapidly evolving and gene set involved formation...
Abstract Hox genes are key developmental regulators that involved in establishing morphological features during animal ontogeny. They commonly expressed along the anterior–posterior axis a staggered, or collinear, fashion. In mollusks, repertoire of body plans is widely diverse and current data suggest their involvement development landmark traits Conchifera, one two major lineages comprises those taxa originated from uni-shelled ancestor (Monoplacophora, Gastropoda, Cephalopoda, Scaphopoda,...
Abstract The mesoderm gives rise to several key morphological features of bilaterian animals including endoskeletal elements and the musculature. A number regulatory genes involved in and/or muscle formation (e.g., Brachyury ( Bra ), even-skipped eve Mox , myosin II heavy chain mhc )) have been identified chiefly from chordates ecdysozoans Drosophila Caenorhabditis elegans but data for non-model protostomes, especially those belonging ecdysozoan sister clade, Lophotrochozoa flatworms,...
Compound eyes in nocturnal or fossorial insects generally express visible light opsins at higher levels than diurnal insects. In this study, we tested whether dorsal (above water) and ventral (below of the four-eyed whirligig beetle Gyretes sericeus Laboulbène, 1853, resemble opsin expression function insect respectively. By immunocytochemistry, compared green LW-opsin rhabdoms ommatidia. Basal rhabdomeres (bR) showed comparable both contrast, inner proximal (R1p) distal (R1d) bR a weak...
Abstract Revealing the mechanisms underlying breath-taking morphological diversity observed in nature is a major challenge Biology. It has been established that recurrent mutations hotspot genes cause repeated evolution of rather simple traits, such as body pigmentation or gain and loss structures. To date, however, it remains elusive whether contribute to natural variation complex size shape organs. Since head morphology pervasive Drosophila , we studied molecular developmental basis...