A5059815957- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Liver Disease and Transplantation
- Peptidase Inhibition and Analysis
- Long-Term Effects of COVID-19
- Cerebral Venous Sinus Thrombosis
- Pancreatitis Pathology and Treatment
- Antifungal resistance and susceptibility
- Hemodynamic Monitoring and Therapy
- Chronic Myeloid Leukemia Treatments
- ECG Monitoring and Analysis
- Lymphoma Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Cardiac, Anesthesia and Surgical Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Dermatological and COVID-19 studies
- Cancer-related molecular mechanisms research
Case Western Reserve University
2020-2023
Massachusetts General Hospital
2022-2023
Cleveland Clinic
2013-2022
Orthopedic Institute
2022
Cleveland Eye Clinic
2020
COVID-19 has been associated with liver injury, and a small subset of patients recovering from severe disease have shown persistent markedly elevated biochemistries for months after infection.To characterize biliary injury COVID-19.A search the pathology archives identified 7 post-COVID-19 clinical, radiologic, pathologic features were assessed.All in this cohort presented respiratory symptoms had complicated clinical course acute elevation biochemistries. Alkaline phosphatase (ALP) was...
Purpose: To develop and train a deep learning-based algorithm for detecting disorganization of retinal inner layers (DRIL) on optical coherence tomography (OCT) to screen cohort patients with diabetic retinopathy (DR). Methods: In this cross-sectional study, subjects over age 18, ICD-9/10 diagnoses type 2 diabetes without Cirrus HD-OCT imaging performed between January 2009 September 2019 were included in study. After inclusion exclusion criteria applied, final total 664 (5992 B-scans from...
Sorsby's fundus dystrophy (SFD) is an inherited blinding disorder caused by mutations in the tissue inhibitor of metalloproteinase-3 (TIMP3) gene. The SFD pathology macular degeneration with subretinal deposits and choroidal neovascularization (CNV) closely resembles that more common age-related (AMD). objective this study was to gain further insight into molecular mechanism(s) which mutant TIMP3 induces CNV. In we demonstrate hyaluronan (HA), a large glycosaminoglycan, elevated plasma...
Patients with chronic liver disease (CLD) were significantly affected by COVID-19. Despite evidence of acute hepatic injury and increased mortality, the long-term effects COVID-19 hospitalization on natural history CLD patients are unknown.
Disorganization of retinal inner layers (DRIL) is a potential spectral-domain optical coherence tomography (SD-OCT) imaging biomarker with clinical utility in diabetic retinopathy (DR).
A 58-year-old man with a history of hypertension and psoriasis presented acute-onset heart failure an ejection fraction 25%-30%. During the work-up, cardiac magnetic resonance imaging showed pattern inflammation consistent sarcoidosis, which was confirmed (18)F-fluorodeoxyglucose positron emission tomography . The patient recently initiated on ixekizumab for psoriasis, then discontinued. This discontinuation resulted in complete resolution establishment normal fraction. result suggests...
This study aimed to investigate the efficacy and safety of subcutaneous injection peginterferon lambda in patients hospitalized with COVID-19.In this (NCT04343976), admitted hospital COVID-19 confirmed by RT-PCR from nasopharyngeal swab were randomly assigned within 48 h receive or placebo a 1:1 ratio. Participants subcutaneously injected saline at baseline day 7 followed up until 14.We enrolled 14 participants; 6 participants (85.7%) group 1 participant (14.3%) treated remdesivir prior...