Calcium phosphates, due to their similarity the inorganic fraction of mineralized tissues, are great importance in treatment bone defects. In order improve biological activity hydroxyapatite (HAP), its fluoride-substituted modification (FAP) was synthesized using sol-gel method and calcined at three different temperatures range 800–1200 °C. Physicochemical properties were evaluated indicate which material would support regeneration best. X-ray diffraction (XRD), scanning electron microscopy...

Purpose: This study was conducted in order to evaluate the clinical utility of MRI detecting cartilage lesions and its dependence on anatomical location lesion grade. Methods: A retrospective analysis reports arthroscopic findings performed 190 consecutive patients treated one orthopaedic department. protocols were prepared by 18 radiologists from 10 different centers with use 1.5 T magnets. The image selected reading radiologists. Four hundred fifty-three chondral five anatomic locations...

Revision surgeries several years after the implantation of prosthesis are unfavorable from patient’s point view as they expose him to additional discomfort, risk complications and expensive. One factors responsible for aseptic loosening is gradual degradation cement material a result working under considerable loads, in an aggressive environment human body. Contaminants present surgical field may significantly affect durability bone and, consequently, entire bone-cement-prosthesis system....

Traumatic injuries are a significant global health concern, with profound medical and socioeconomic impacts. This study explores the patterns of trauma-related hospitalizations in Lublin Province Poland, particular focus on periods before during COVID-19 pandemic. The primary aim this research was to assess trends trauma admissions, average length hospital stays, mortality rates associated different types injuries, comparing urban rural settings over two distinct time periods: 2018-2019...

According to some authors, serum selenium levels are strongly associated with the severity of liver diseases, including cirrhosis. The aim this study was determine relationship between concentration and pro-inflammatory profibrotic cytokines-interleukin-6 (IL-6) growth differentiation factor 15 (GDF-15) in patients alcoholic parameters studied were determined 99 cirrhosis divided based on disease according Child-Turcotte-Pugh criteria. In cirrhosis, statistically lower, whereas IL-6 GDF-15...

The BIRC5 gene encodes a survivin protein belonging to class III of inhibitors apoptosis, IAP. This serves dual role. First, it regulates cell death, and second, is an important regulator mitosis progression, although its physiological regulatory function has not been fully understood. Many studies have shown confirmed that practically absent in mature tissues nature, while overexpression reported many cancerous tissues. There little information about the significance expression normal adult...

Abstract Background Acute myeloid leukemia (AML) is a heterogenic lethal disorder characterized by the accumulation of abnormal progenitor cells in bone marrow which results hematopoietic failure. Despite various efforts detection and treatment, many patients with AML die this cancer. That why it important to develop novel therapeutic options, employing strategic target genes involved apoptosis tumor progression. Methods The aim study was evaluate PARP1, PARP2, PARP3, TRPM2 gene expression...

The paper presents the results of experimental strength tests specimens made two commercially available bone cements subjected to compression, that is a typical variant load this material during use in human body, after it has been used for implantation prostheses or supplementation defects. One factors analysed detail was duration cement seasoning Ringer's solution simulates aggressive environment body and degradation caused by it. study also focused on parameters quantitative deviation...

The COVID-19 pandemic demanded changes in healthcare systems worldwide. lockdown brought about difficulties access. However, trauma still required further attention considering its modifications. presented study aims to investigate the variances epidemiological patterns of during and previous year, with a view better understand modifications provision. authors analyzed data from first 2020 (12 March–30 May) same period 2019 35 hospitals Lublin Province. A total 10,806 patients 5212 were...

A novel fluorapatite/glucan composite ("FAP/glucan") was developed for the treatment of bone defects. Due to presence polysaccharide polymer (β-1,3-glucan), is highly flexible and thus very convenient surgery. Its physicochemical microstructural properties were evaluated using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), mercury intrusion, mechanical testing compared with reference material, which a hydroxyapatite/glucan ("HAP/glucan") hydroxyapatite...

According to some authors, the serum selenium level is strongly associated with severity of liver diseases including cirrhosis. The aim study was determine relationship between concentration and pro-inflammatory profibrotic cytokines – interleukin-6 (IL-6) growth differentiation factor 15 (GDF-15) in patients alcoholic parameters studied were determined 99 cirrhosis divided based on disease according Child-Turcotte-Pugh criteria. In cirrhosis, statistically lower whereas IL-6...

Background: There is a lack of research on social image, prestige, and the position paramedic profession in structure. The main objective study was to determine place hierarchy prestige professions as viewed by public. In operationalizing term ‘prestige’, we deemed word ‘respect’ best fit sense subjective evaluation with regard profession. Material methods: data comes from cross-sectional survey-based research. carried out group 600 people over 18 years age. sample random nature, selection...

Some reports in the literature show advantages of fluoride-containing apatite ceramics over hydroxyapatite (HAP), at least some aspects. While HAP has been used extensively treatment bone defects, fluoridated hardly tested vivo. In order to verify biological properties fluoride-doped and assess its therapeutic potential, we synthesized fluorapatite (FAP) applied it as a filling defects experimental animals (rabbits). The effects were evaluated on extracted bones after 3 6 months from...

Abstract Biomaterials for bone tissue regeneration, including polymer‐based composites, are typically evaluated in vitro prior to the clinical trials. However, such composites tested vivo may behave different due specific body conditions. For example, some implanted into acidified transient postoperative inflammation unexpectedly swell which delays wound healing. Such massive swelling acidic medium was previously observed new elastic hydroxyapatite (HAp)/β‐glucan biomaterial. further cases...

Head and neck injuries are a heterogeneous group in terms of both clinical course prognosis. For years, there have been attempts to create an ideal tool predict the outcomes severity injuries. The aim this study was evaluation use selected artificial intelligence methods for outcome predictions head injuries.6,824 consecutive cases patients who sustained injuries, treated hospitals Lublin Province between 2006-2018, whose data provided by National Institute Public Health / Hygiene, were...

Abstract Introduction. Injuries are an extremely important public health problem, in both developed and developing countries. Various traumas contribute to some one third of deaths the entire human population followed by cardiovascular diseases cancer only. Understanding epidemiology trauma might improve hospitals’ ability provide proper diagnoses treatment. Aim. The aim this study was epidemiological characteristics injuries analyzed group patients. Material methods. A retrospective...

Injuries are an extremely important problem in public life and account for up to one-third of deaths the entire human population. Available trauma scoring systems provide a good estimation mortality; however, some factors affect their utility daily practice. Therefore, new easily applicable any given country system has been developed proposed this study.A retrospective study medical records 485 patients were evaluated, together with diagnostic performance regard mortality, was calculated...

Abstract Background: Acute myeloid leukemia (AML) is a heterogenic lethal disorder characterized by the accumulation of abnormal progenitor cells in bone marrow which results hematopoietic failure. Despite various efforts detection and treatment, many patients with AML die this cancer. That why it important to develop novel therapeutic options, employing strategic target genes involved apoptosis tumor progression. Methods: The aim study was evaluate PARP1, PARP2, PARP3, TRPM2 gene expression...

The heterogeneous population of patients affected by trauma is extremely difficult to systematize. This due the diversity mechanisms injury, nature and severity injury population, which relate injuries, diverse in terms gender, age, presence comorbidities that make up final a certain degree danger life.To develop universal method assess loss life resulting from their consequences, using parameters available Polish administrative databases, similar diagnostic efficacy as other used scales...

Abstract Introduction. Parental alcohol abuse hinders a child’s development, which means that these children are more exposed to mental health problems. Aim. The aim of this study was analyze the link between intensity eating disorders in youngsters and family alcoholism. Material methods. conducted among adolescents Lubelskie province. 1766 students, aged 12 22 were participants study. authors used method called Eating Disorder Inventory, as well self-designed questionnaire included...