A5032558301- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- AI in cancer detection
- Advanced MRI Techniques and Applications
- COVID-19 and healthcare impacts
- Digital Radiography and Breast Imaging
- Global Cancer Incidence and Screening
- Hepatocellular Carcinoma Treatment and Prognosis
- Lipoproteins and Cardiovascular Health
- Cancer Cells and Metastasis
- Cardiac electrophysiology and arrhythmias
- Cancer Risks and Factors
- Ultrasound and Hyperthermia Applications
- Multiple and Secondary Primary Cancers
- Liver Disease Diagnosis and Treatment
- Optical Imaging and Spectroscopy Techniques
- Gastric Cancer Management and Outcomes
- Ultrasound Imaging and Elastography
- Computational Drug Discovery Methods
- Soft tissue tumor case studies
- Thyroid Cancer Diagnosis and Treatment
- Radiology practices and education
Sapienza University of Rome
2011-2024
Policlinico Umberto I
2007-2022
Howard Hughes Medical Institute
2019
Wellcome Trust
2019
University of Salento
2014-2016
Purpose To prospectively compare gadoxetate disodium–enhanced magnetic resonance (MR) imaging with multiphasic 64-section multidetector computed tomography (CT) in the detection of hepatocellular carcinoma (HCC) patients cirrhosis. Materials and Methods Institutional review board approval informed patient consent were obtained for this prospective study. Fifty-eight (39 men, 19 women; mean age, 63 years; age range, 35–84 years) underwent MR CT. The examinations performed within 30 days each...
Abstract Background Breast cancer (BC) includes different pathological and molecular subtypes. This study aimed to investigate whether multiparametric magnetic resonance imaging (mpMRI) could reliably predict the status of BC, comparing mpMRI features with immunohistochemical results. Methods retrospective included 156 patients an ultrasound-guided biopsy-proven who underwent breast (including diffusion-weighted imaging) on a 3-T scanner from 2017 2020. Histopathological analyses were...
Abstract Background To assess the reliability and comprehensibility of breast radiology reports simplified by artificial intelligence using large language model (LLM) ChatGPT-4o. Methods A radiologist with 20 years’ experience selected 21 anonymized reports, 7 mammography, ultrasound, magnetic resonance imaging (MRI), categorized according to reporting data system (BI-RADS). These underwent simplification prompting ChatGPT-4o “Explain this medical report a patient simple language”. Five...
Background Ductal carcinoma in situ (DCIS) is often reclassified as invasive cancer the final pathology report of surgical specimen. It significant clinical relevance to acknowledge possibility underestimating disease when utilizing preoperative biopsies for a DCIS diagnosis. In cases where such histologic upgrades occur, it imperative consider them planning process, including potential inclusion sentinel lymph node biopsy due risk axillary metastasis. Purpose To assess capability breast...
Abstract Objectives The Node-RADS score was recently introduced to offer a standardized assessment of lymph node invasion (LNI). We tested its diagnostic performance in accurately predicting LNI breast cancer (BC) patients with magnetic resonance imaging. study also explores the consistency across three readers. Materials and methods A retrospective conducted on BC who underwent preoperative contrast-enhanced imaging dissection between January 2020 2023. Sensitivity, specificity, positive...
The purpose of this study was to investigate MRI features triple-negative breast cancer (TNBC) compared with non-TNBC, predict histopathological results. In the study, 26 patients TNBC and 24 non-TNBC who underwent multiparametric on a 3 T magnet over 10-months period were retrospectively recruited. MR imaging sets evaluated by two experienced radiologists in consensus classified according 2013 American College Radiology (ACR) BI-RADS lexicon. comparison between groups performed using...
The aim of this prospective study was to compare the diagnostic performance contrast-enhanced mammography (CEM) versus digital (DM) combined with breast ultrasound (BUS) in women dense breasts. Between March 2021 and February 2022, patients eligible for CEM composition category ACR BI-RADS c-d at DM an abnormal finding (BI-RADS 3-4-5) and/or BUS were considered. During CEM, a nonionic iodinated contrast agent (Iohexol 350 mg I/mL, 1.5 mL/kg) power-injected intravenously. Images evaluated...
To evaluate the accuracy in lesion detection and size assessment of Unenhanced Magnetic Resonance Imaging combined with Digital Breast Tomosynthesis (UE-MRI+DBT) Dynamic Contrast Enhanced (DCE-MRI), women known breast cancer.A retrospective analysis was performed on 84 patients histological diagnosis cancer, who underwent MRI a 3T scanner DBT over 2018-2019, our Institution. Two radiologists, 15 7 years experience imaging respectively, reviewed DCE-MRI UE-MRI (including DWI T2-w) + images...
The role of functional techniques, such as magnetic resonance spectroscopy (H-MRS), noninvasive tools to increase breast MR imaging reliability has been widely investigated during the last 2 decades. Considering growing interest in tumor biology and its influence on parameters, aim this study was investigate relationship between H-MRS parameters cancer biomarkers evaluate whether results at 3 T can correlate with established prognostic factors our clinical experience.One hundred two patients...
Penetration and abscess formation in an adjacent parenchymal organ as presentation of a colon cancer is very uncommon. We report rare case pyogenic liver the first manifestation infiltrative penetrating hepatic flexure carcinoma without metastases. A 50-year-old woman was admitted with right abdominal pain, fever chills. The initial diagnosis abscess. Subsequent CT scan colonoscopy evidenced abscessed within segment 6 liver. Eight months after colectomy resection there no evidence disease....
The cholesteryl ester transfer protein (CETP) mediates the of esters from high-density lipoproteins (HDL) to triglyceride (TG)-rich lipoproteins. A consistent number investigations has suggested an association between TaqIB polymorphism CETP gene, plasma HDL-C levels and risk cardiovascular disease, but results are controversial. aim this study was determine if might be related presence atrial fibrillation (AF). We conducted a case-control study, enrolling 109 Caucasian unrelated patients...
To investigate the association between body composition parameters, sarcopenia, obesity and prognosis in patients with metastatic ER+/HER2- breast cancer under therapy cyclin-dependent kinase (CDK) 4/6 inhibitors.92 biopsy-proven cancer, treated CDK inhibitors 2018 2021 at our center, were included this retrospective analysis. Visceral Adipose Tissue (VAT), Subcutaneous (SAT) Skeletal Muscle Index (SMI) measured before starting (Palbociclib, Abemaciclib or Ribociclib). Measurements performed...
The aim of this study was to evaluate the added value digital breast tomosynthesis (DBT) when combined with mammography (DM) in BI-RADS assessment and follow-up management.From February 2014 January 2015, 214 patients underwent DM DBT, acquired a Siemens Mammomat Inspiration unit. 2 expert readers independently reviewed studies steps: DM+DBT, according rate. Patients 0, 3, 4, 5 were recalled for work-up. Inter-reader agreement rate work-up evaluated using Cohen's kappa.Inter-reader (κ value)...