Purpose: To evaluate the efficacies and treatment outcomes following intravitreal bevacizumab (IVB), ranibizumab (IVR), laser photocoagulation (LPC) in retinopathy of prematurity (ROP).Methods: This was a retrospective interventional case series study including data 134 infants (264 eyes) who were treated with IVB, IVR, or LPC for ROP. The collected from two major ROP centers Turkey without any randomization masking. Regression ROP, recurrence profile, complications after each modality,...

Purpose: To evaluate 2-year outcomes following intravitreal bevacizumab (IVB) as monotherapy for aggressive posterior retinopathy of prematurity (APROP). Methods: Medical records 40 infants were retrospectively reviewed. Group I included who had received IVB injections APROP. II underwent laser treatment Anatomic and refractive the presence anisometropia strabismus assessed at follow-up examinations. Results: 48 eyes 25 (11 males) with a mean gestational age (GA) 26.40 ± 1.82 weeks birth...

Purpose: To compare tear film osmolarity (TFO) and other dry eye tests between diabetic children normal healthy children.Materials Methods: Twenty-six (Group 1) 20 without any ocular and/or systemic disorder 2) were enrolled in the study. Detailed surface assessment including, disease index (OSDI) questionnaire, TFO measurement (Tear Lab Osmolarity System, San Diago, CA, USA), corneal epithelial thickness (CET) using anterior segment optical coherence tomography (OCT) (RTVue CAM, Optovue...

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

We have investigated the risk factors that lead to severe retinopathy of prematurity using statistical analysis and logistic regression as a form generalized additive model (GAM) with pairwise interaction terms (GA2M). In this process, we discuss trade-off between accuracy interpretability these machine learning techniques on clinical data. also confirm intuition expert neonatologists few factors, such gender, were previously deemed clinically not significant in RoP prediction.

Context: The presence of dry eye syndrome (DES) in ocular allergic diseases was evaluated several studies. Despite this, little exists about the tear film instability atopic children including patients with rhinitis (AR), conjunctivitis (AC) and asthma. This is a study which presents intriguing findings regarding relationship clinical aspects children.Objective: To determine AR, AC asthma.Materials methods: One hundred thirty-five consecutive asthma as group 45 without any systemic...

Purpose: To assess ocular biometric outcomes following intravitreal bevacizumab (IVB) monotherapy for retinopathy of prematurity (ROP) and compare these results with those laser photocoagulated infants the ones spontaneously regressed ROP.Materials methods: Premature including who underwent IVB (Group 1) or photocoagulation 2) ROP 3) were recruited study. Refractive errors parameters (Axial length [AL], anterior chamber depth [ACD], lens thickness [LT]) measured at adjusted 1 year age in all...

To demonstrate the clinical characteristics and treatment outcomes of severe retinopathy prematurity (ROP) in preterm infants with birth weight (BW) above 1500 g Turkey.A retrospective review 5920 ROP records was performed Zeynep Kamil Maternity Children's Diseases Training Research Hospital. The were obtained from center same institute between 2011 2016. data comprised demographic including, gestational age, BW, systemic risk factors, zone stage ROP, type, modality, inborn/outborn status...

Two patients with no symptoms of hypertension in their medical history before pregnancy were referred to the obstetrics emergency clinic and visual complaints. After physical examination laboratory tests, one was diagnosed severe preeclampsia while other HELLP syndrome (Hemolysis-Elevated Liver enzymes-Low Platelets). Ocular examinations performed after delivery due patients' worsening The preeclamptic patient showed bilateral serous retinal detachment (SRD) macular hemorrhage. Systemic...

To report the effectiveness and safety of primary 23-Gauge (G) vitreoretinal surgery for rhegmatogenous retinal detachment (RRD).In this retrospective study, 49 eyes consecutive patients who underwent 23-G transconjunctival sutureless vitrectomy (TSV) RRD between January 2007 July 2009 at our institution were evaluated.Mean follow-up time was 8.9±7.7 months (1-28 months). Retinal reattachment achieved with a single operation in 47(95.9%) eyes. In two (4.1%), redetachment due to new breaks...

To evaluate the central corneal thickness (CCT) measurements of premature infants.The infants who were born between 25-34wk gestational age (GA) retrieved for study. All CCT performed within first 2d their life under topical anesthesia by using an ultrasonic pachymeter.The mean 200 eyes was 647.79±63.94 µm. The right and left similar (647.30±64.72 µm 648.29±63.47 consecutively). girls 642.08±54.89 boys 653.07±71.14 µm, with no statistically significant difference (P>0.05). But there a...

Amaç: Klinik pratikte kullanılan iki el tipi taşınabilir otorefraktometre [Nidek HandyRef-K, Nidek, Tokyo, Japonya (HRK); Welch Allyn Spot Vision Screener, NewYork, ABD (WA)] ile pediatrik hasta grubunda elde edilen refraktif sonuçların karşılaştırılması amaçlandı. Gereç ve Yöntemler: Göz polikliniğine başvuran 1-10 yaş arasındaki çocuk hastalar, bu kesitsel gözlemsel çalışma kapsamına alındı. Yüz elli sekiz hastanın 158 gözünün refraksiyon değeri önce HRK sonra WA otorefraktometreleri...

INTRODUCTION: Retinopathy of prematurity (ROP) is one the main reasons preventable childhood blindness. In development ROP, MicroRNAs may be effective in balance factors that inhibit and activate angiogenic factors. We aimed to determine changes blood levels miR-146a, miR-143, miR-210, miR-21, miR-126, miR-211, miR-221, miR-106 let 7f investigate their association with ROP. hypothesed level these miRNAs changed significantly ROP cases. MATERIALS AND METHODS: This observational study was...

Purpose: To evaluate retinal nerve fiber layer thickness (RNFLT), ganglion cell (GCLT), subfoveal choroidal (SFCT), and central (CRT) in asthmatic children who were under inhaled corticosteroid treatment by using Swept-Source Optical Coherence Tomography (SS-OCT).Material methods: Fifty-three prospectively analyzed the study. Group 1 included 31 group 2 22 healthy children. Asthmatic received a dose 250 μg daily of fluticasone propionate (Flexotide, GlaxoSmithKline, Middlesex, UK). Allergy...

To define late-stage fluorescein angiography (FA) findings in patients who received anti-vascular endothelial growth factor (VEGF) agents (intravitreal bevacizumab or aflibercept) as a treatment for stage 3 retinopathy of prematurity (ROP) zone II. We also compared the untreated eyes.Infants with history ROP underwent were evaluated retrospectively. The divided into 2 groups: those anti-VEGF and regressed spontaneously without treatment. Vascular abnormalities, such vascular leakage, shunts...

We aimed to assess ocular surface characteristics in children with Hashimoto's thyroiditis without thyroid-associated ophthalmopathy and compare the results those of healthy children.Twenty-two (Group 1) 20 any and/or systemic disorder 2) were enrolled study. Ocular Surface Disease Index questionnaire, tear film osmolarity measurement (TearLab Osmolarity System, San Diego, CA, USA), Schirmer breakup time tests, meibography, conjunctival brush cytology performed compared between groups.The...

To evaluate the effect of a single intravitreal bevacizumab (IVB) injection on blood flow parameters in ophthalmic artery (OA) and middle cerebral (MCA) infants with retinopathy prematurity (ROP).This prospective interventional study included 15 ROP who were treated IVB. Peak systolic velocity (PSV), end-diastolic velocity, mean (MV) resistivity index measured using pulse wave Doppler ultrasonography (Philips En Visor C, Amsterdam, The Netherlands) OA MCA, before IVB 1 day, week month after...

Background: To assess Factor V Leiden (FVL) (rs6025), Prothrombin G20210A (rs1799963), MTHFR C677T (rs1801133), and A1298C (rs1801131) gene mutations as risk factors in the development of retinopathy prematurity (ROP).Materials methods: A total 105 children were included this cross-sectional study. Patients divided into two groups. The study group consisted 55 infants with a history ROP control comprised 50 healthy term birth. All subjects screened for presence certain (FVL, G20210A, A1298C)...

To evaluate changes in retrobulbar ocular blood flow parameters by using Colour Doppler Imaging (CDI) and foveal microvasculature Optical Coherence Tomography Angiography (OCTA) pediatric obese patients to compare them with a group of healthy children.Children diagnosed obesity without hypertension diabetes (39 subjects, group) age-matched controls (26 control underwent CDI OCTA imaging. Peak systolic velocity, end-diastolic velocity resistivity index from ophthalmic, central retinal...

Amaç: Prematüre retinopatisi (PR) sıklığı ve risk faktörlerinin belirlenmesi Gereç Yöntemler: Dört yıllık sürede (1 Ocak 2011 - 27 Aralık 2014) yenidoğan yoğun bakım ünitemizde takip edilen, gebelik yaşı ≤ 32 hafta veya doğum ağırlığı 1500 g 888 preterm yenidoğanın PR tarama sonuçları geriye dönük olarak değerlendirildi. Tedavi alan almayan pretermlerin verileri Student T Ki kare testleri ile karşılaştırıldı. tedavisi için anlamlı bulunan değişkenler bağımsız faktörleri açısından lojistik...