A5037385573- Neurotransmitter Receptor Influence on Behavior
- Receptor Mechanisms and Signaling
- Memory and Neural Mechanisms
- Photoacoustic and Ultrasonic Imaging
- Olfactory and Sensory Function Studies
- Cardiac electrophysiology and arrhythmias
- Neuroscience and Neuropharmacology Research
- Optical Imaging and Spectroscopy Techniques
- Tryptophan and brain disorders
- Neuroendocrine regulation and behavior
- Anesthesia and Neurotoxicity Research
- Advanced Chemical Sensor Technologies
National Institute on Drug Abuse
2018-2021
Icahn School of Medicine at Mount Sinai
2021
National Institutes of Health
2019
Oregon Health & Science University
2019
Cornell University
2019
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency ('incubate') over time. Animal models of incubation may help develop treatments to prevent relapse, but these have ubiquitously focused on the role conditioned stimuli (CSs) signaling delivery. Discriminative (DSs) are unique in that they exert stimulus-control both taking and seeking behavior difficult extinguish. For this reason, excitatory effects DSs signal availability, not yet...
Current functional imaging techniques, such as magnetic resonance imaging, rely upon activity-induced blood flood changes to neurons. This indirect measurement of neuronal activity inherently limits image resolution and specificity, however, advances in transgenic technology Photoacoustic (PA) methodology have offered new solutions. We previously demonstrated using PA conjunction with a Fos-LacZ rat model map activated neurons through selective formation PA-active X-gal product within...
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency ('incubate') over time. Animal models of incubation may help in developing treatments for relapse prevention. However, these have primarily focused on the role conditioned stimuli (CSs) signaling delivery and not discriminative (DSs), which signal availability are also known to play a major relapse. We recently showed that DS-controlled cocaine seeking rats incubates during...
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency ('incubate') over time. Animal models of incubation may help develop treatments to prevent relapse, but these have ubiquitously focused on the role conditioned stimuli (CSs) signaling delivery. From a translational perspective this is problematic because people encounter only during or after relapse. For reason, in response discriminative (DSs) that signal availability before not...