A5081001020- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Non-Invasive Vital Sign Monitoring
- Blood Pressure and Hypertension Studies
- Enhanced Recovery After Surgery
- Anesthesia and Sedative Agents
- Cardiovascular Health and Disease Prevention
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Heart Rate Variability and Autonomic Control
- Healthcare Technology and Patient Monitoring
- Anesthesia and Pain Management
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Cardiac pacing and defibrillation studies
- Cardiac Valve Diseases and Treatments
- Ultrasound in Clinical Applications
- Intensive Care Unit Cognitive Disorders
- Renal function and acid-base balance
- Artificial Intelligence in Healthcare and Education
- Cardiac Arrhythmias and Treatments
- Surgical Simulation and Training
- Respiratory Support and Mechanisms
- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Anesthesia and Neurotoxicity Research
University of California, Los Angeles
2016-2025
Ronald Reagan UCLA Medical Center
2017-2024
University of Vermont
2024
Foundation for the National Institutes of Health
2022
University of California, Irvine
2011-2021
UCLA Health
2017-2021
Université Libre de Bruxelles
2017-2021
Université Paris-Saclay
2019-2021
Université Paris Cité
2021
University of California, San Diego
2021
Background— Mechanical dyssynchrony is a potential means to predict response cardiac resynchronization therapy (CRT). We hypothesized that novel echocardiographic image speckle tracking can quantify and CRT. Methods Results— Seventy-four subjects were studied: 64 heart failure patients undergoing CRT (aged 64±12 years, ejection fraction 26±6%, QRS duration 157±28 ms) 10 normal controls. Speckle applied routine midventricular short-axis images calculated radial strain from multiple...
Respiratory arterial pulse pressure variations (PPV) are the best predictors of fluid responsiveness in mechanically ventilated patients during general anesthesia. However, previous studies were performed a small number and determined single cutoff point to make clinical discrimination. The authors sought test predictive value PPV large, multicenter study express it using gray zone approach.The studied 413 anesthesia mechanical ventilation four centers. PPV, central venous pressure, cardiac...
Abstract Editor’s Perspective What We Already Know about This Topic Article Tells Us That Is New Background With appropriate algorithms, computers can learn to detect patterns and associations in large data sets. The authors’ goal was apply machine learning arterial pressure waveforms create an algorithm predict hypotension. detects early alteration that herald the weakening of cardiovascular compensatory mechanisms affecting preload, afterload, contractility. Methods developed with two...
Several studies have demonstrated that perioperative hemodynamic optimization has the ability to improve postoperative outcome in high-risk surgical patients. All of these aimed at optimizing cardiac output and/or oxygen delivery period. We conducted a survey with American Society Anesthesiologists (ASA) and European Anaesthesiology (ESA) assess current management practices patients undergoing surgery Europe United States.A including 33 specific questions was emailed 2,500 randomly selected...
Perioperative fluid therapy remains a highly debated topic. Its purpose is to maintain or restore effective circulating blood volume during the immediate perioperative period. Maintaining and pressure are key components of assuring adequate organ perfusion while avoiding risks associated with either hypo- hyperperfusion. Relative therapy, three inescapable conclusions exist: overhydration bad, underhydration what we assume about status our patients may be incorrect. There wide variability...
The United States is in the midst of an opioid epidemic, and use disorder often begins with a prescription for acute pain. perioperative period represents important opportunity to prevent chronic use, recently there has been paradigm shift toward implementation enhanced recovery after surgery (ERAS) protocols that promote opioid-free multimodal analgesia. objective this study was assess impact ERAS intervention colorectal on discharge prescribing practices.We conducted historical-prospective...
Enhanced recovery may be viewed as a comprehensive approach to improving meaningful outcomes in patients undergoing major surgery. Evidence support enhanced pathways (ERPs) is strong colorectal There some controversy about the adoption of specific elements "bundles" because relative importance different components ERPs hard discern (a consequence multiple simultaneous changes clinical practice when are initiated). evidence that approaches fluid management better than alternatives surgery;...
Background The Hypotension Prediction Index (the index) software is a machine learning algorithm that detects physiologic changes may lead to hypotension. original validation used case control (backward) analysis has been suggested be biased. This study therefore conducted cohort (forward) and compared this the technique. Methods A retrospective of data from previously reported studies was conducted. All were analyzed identically with two different methodologies, receiver operating...
The imbalance in anesthesia workforce supply and demand has been exacerbated post-COVID due to a surge for care, especially non–operating room anesthetizing sites, at faster rate than the increase clinicians. consequences of this or labor shortage compromise healthcare facilities, adversely affect cost worsen burnout, disrupt procedural surgical schedules, threaten academic missions ability educate future anesthesiologists. In developing possible solutions, one must examine emerging trends...
Respiratory variations in pulse oximetry plethysmographic waveform amplitude (DeltaPOP) are related to respiratory pressure (DeltaPP) and sensitive changes preload. The authors hypothesized that DeltaPOP can predict fluid responsiveness mechanically ventilated patients during general anesthesia.Twenty-five referred for cardiac surgery were studied after induction of anesthesia. Hemodynamic data (cardiac index, central venous pressure, pulmonary capillary wedge DeltaPP, DeltaPOP) recorded...
In Brief BACKGROUND: Respiratory variations in arterial pulse pressure (ΔPP) are accurate predictors of fluid responsiveness mechanically ventilated patients. The aim our study was to assess the ability a novel algorithm for automatic estimation stroke volume variation (SVV) predict METHODS: We studied 25 patients referred coronary artery bypass grafting. SVV continuously displayed by Vigileo/FloTrac system. All were under general anesthesia, mechanical ventilation and also monitored with...
Respiratory variation in arterial pulse pressure is a reliable predictor of fluid responsiveness mechanically ventilated patients with circulatory failure. The main limitation this method that it requires an invasive catheter. Both and oximetry plethysmographic waveforms depend on stroke volume. We conducted prospective study to evaluate the relationship between respiratory (POP) waveform amplitude.This clinical investigation was 22 patients. POP amplitude were recorded simultaneously...
WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: The authors tested the hypothesis that deep neural networks trained on intraoperative features can predict postoperative in-hospital mortality.The data used to train and validate algorithm consists of 59,985 patients with 87 extracted at end surgery. Feed-forward a logistic output were using stochastic gradient descent momentum. 80% data, 20% reserved for testing. assessed improvement network by adding American Society Anesthesiologists...
In Brief BACKGROUND: Respiratory variations in the pulse oximeter plethysmographic waveform amplitude (ΔPOP) are sensitive to changes preload and can predict fluid responsiveness mechanically ventilated patients. However, they cannot be easily calculated from a bedside monitor. Pleth variability index (PVI, Masimo Corp., Irvine, CA) is new algorithm that automatically calculates ΔPOP. The aim of our study was test ability this device continuously monitor METHODS: Twenty-five patients were...
Abstract Background: The perioperative surgical home model highlights the need for trainees to include modalities that are focused on entire experience. focus of this study was design, introduce, and evaluate integration a whole-body point-of-care (POC) ultrasound curriculum (Focused periOperative Risk Evaluation Sonography Involving Gastroabdominal Hemodynamic Transthoracic ultrasound) into residency training. Methods: For 2 yr, anesthesiology residents (n = 42) received lectures using...
Unrecognized malposition of the endotracheal tube (ETT) can lead to severe complications in patients under general anesthesia. The focus this double-blinded randomized study was assess accuracy point-of-care ultrasound verifying correct position ETT and compare it with auscultation.Forty-two adult requiring anesthesia were consented. Patients right main bronchus, left or tracheal intubation. After randomization, placed via fiber-optic visualization. Next, location assessed using auscultation...