- Vaccine Coverage and Hesitancy
- HIV Research and Treatment
- Viral Infections and Outbreaks Research
- HIV-related health complications and treatments
- HIV/AIDS drug development and treatment
- Disaster Response and Management
- Immune Cell Function and Interaction
- Travel-related health issues
- Influenza Virus Research Studies
- COVID-19 epidemiological studies
- Reproductive System and Pregnancy
Mildmay Uganda
2024-2025
Makerere University
2023-2025
University of Siena
2025
<title>Abstract</title> <bold>Introduction: </bold>Despite the effectiveness of female condoms (FCs) in preventing sexually transmitted infections, their use remains low. University students, at high risk for unsafe sex, need targeted interventions. This study assessed knowledge and utilization among undergraduates to inform policies strategies improving accessibility uptake higher education institutions. <bold>Methods: </bold>A cross-sectional was conducted 246 undergraduate students...
As the Coronavirus Disease 2019 (COVID-19) pandemic overwhelmed healthcare systems globally, integrating vaccination into primary health services became essential to expedite immunization efforts, especially in resource-constrained settings. This report explains multifaceted process of COVID-19 at Mildmay Hospital Uganda (MUgH), focusing on strategies, challenges and outcomes associated with this project. MUgH, a general hospital Uganda, implemented between March 2021 December 2022. Using 7...
<title>Abstract</title> <bold>Introduction:</bold> This study evaluated the effectiveness of Antiretroviral Therapy (ART) and associated factors on viral-suppression before, during, after pregnancy (maternal timeline).<bold>Methods</bold> We conducted a cohort study, retrospectively reviewing records 1,291 pregnant women ART. Descriptive statistics summarised demographics clinical characteristics. Chi-square, Fisher’s exact, Generalised Estimating Equations logistic regression assessed...
Introduction: Unrecognized Ebola Virus Disease (EVD) can lead to multiple chains of transmissions if the first caretakers are not trained and prepared. This study aimed assess healthcare workers (HCWs) preparedness in private hospitals located Kampala, detect, respond prevent EVD. Methodology: A descriptive cross-sectional was carried out among HCWs direct clinical care provision four hospitals, one Treatment Unit (ETU) using a self-administered questionnaire from March June 2020. Results:...
<title>Abstract</title> Dolutegravir (DTG), a key component of the recommended HIV treatment regimens in Uganda, has been associated with hyperglycemia. We evaluated its influence on hyperglycemia risk to create stratification tool guide patients’ monitoring. conducted prospective cohort study at three selected sites, involving 628 patients who had Tenofovir Disoproxyl Fumarate, Lamivudine, and (TLD). Patients were divided into those prior Nucleoside reverse transcriptase inhibitors...
Dolutegravir (DTG), a key component of the recommended human immunodeficiency virus (HIV) treatment regimens in Uganda, has been associated with hyperglycemia. We evaluated its influence on hyperglycemia risk to create stratification tool for patient monitoring.
<title>Abstract</title> Introduction: Cytokine dysregulation is a key feature of HIV-1 infection with plasma Interleukin 6 (IL-6) largely observed to enhance replication whereas Interferon gamma (IFN-γ) inhibits it. Notably, IL-6 IFN-γ secretion through the STAT3 pathway support survival. High IL-6: ratios may thus be linked persistence. Although these cytokines are often evaluated separately, we assessed ratio as predictor immune state and viral suppression. Methodology: A cross-sectional...
Despite the huge benefits of vaccination, vaccine uptake around globe is surprisingly suboptimal in most places; explanations include hesitancy and increasingly well-organized anti-vaccine groups. In addition, WHO identified structural gaps many countries for delivery vaccination services, specifically a lack scientifically sound NITAGs highest integrity, as well political will implementation. Here country systems were evaluated using simple 4×2 managerial criteria (having goals, one plan,...
We highlight a young vaccinologist's struggles upon returning to resource-limited country after training abroad. Despite the urgency of vaccination against endemic, epidemic, and pandemic diseases, daunting obstacles persist. also propose suggestions opportunities for meeting these challenges – making vaccines more accessible global public health.