A5003981455- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
- Urticaria and Related Conditions
- Autoimmune Bullous Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Ocular Oncology and Treatments
- Ocular Diseases and Behçet’s Syndrome
- RNA and protein synthesis mechanisms
- Nonmelanoma Skin Cancer Studies
- Gastrointestinal Tumor Research and Treatment
- Retinal Imaging and Analysis
- Connective tissue disorders research
- Antimicrobial Peptides and Activities
- Gastric Cancer Management and Outcomes
- Drug-Induced Ocular Toxicity
- Food Allergy and Anaphylaxis Research
- Ocular Infections and Treatments
- Diversity and Career in Medicine
- Acne and Rosacea Treatments and Effects
- Medical and Biological Ozone Research
- Colorectal Cancer Treatments and Studies
McGill University
2014-2025
Université de Montréal
2018-2025
Harvard University
2023-2025
Boston University
2025
Centre Hospitalier de l’Université de Montréal
2015-2024
Johns Hopkins Medicine
2020-2021
Johns Hopkins University
2020-2021
University College London
2021
Moorfields Eye Hospital
2021
Moorfields Eye Hospital NHS Foundation Trust
2021
Purpose: Corneal blindness is mainly treated by cornea transplantation. However, there a shortage of donors for surgeries in many countries. Even with accessible donors, patients suffering from severe pathologies causing inflammation may not benefit as they are at high risk graft rejection. The Griffith laboratory the first to use acellular human collagen implants regenerate high‐risk corneas group patients. For broader clinical applications, scalable collagen‐like peptide (CLP) synthetic...
Purpose: Corneal blindness is mainly treated by cornea transplantation. However, there a shortage of donors for surgeries in many countries. Even with accessible donors, patients suffering from severe pathologies causing inflammation may not benefit as they are at high risk graft rejection. The Griffith laboratory the first to use acellular human collagen implants regenerate high‐risk corneas group patients. For broader clinical applications, scalable collagen‐like peptide (CLP) synthetic...
Purpose: To report a case of herpes zoster ophthalmicus (HZO) reactivation after recombinant vaccination. Methods: A 78-year-old woman, with history HZO 20 years ago, was referred for progressive corneal thinning in her left eye that started 1 week second dose Results: At presentation, visual acuity counting fingers. Corneal sensation markedly decreased. Slit lamp examination revealed temporal paracentral epithelial defect 1.5 × 2.0 mm size 40% and surrounding stromal inflammation suggestive...
The aim of this study was to determine the frequency clinically unsuspected ocular surface squamous neoplasia (OSSN) in cases biopsied pterygium (PT).We reviewed 15,016 presented at Henry C. Witelson Ocular Pathology Laboratory during period 1993-2013. All with a clinical diagnosis PT were included. Histopathological diagnoses and demographic data retrieved from histopathological request forms. associated OSSN re-evaluated independently by two pathologists. classification made based on Armed...
Purpose: We report, for the first time, 2 cases of corneal ulceration and perforation after treatment with dupilumab atopic dermatitis. Methods: A 30-year-old woman a 44-year-old man developed unilateral severe while on therapy 3 9 months, respectively. Results: Corneal cultures were negative in both except scanty growth Staphylococcus species enrichment. Both progressed to despite intensive topical antibiotic treatment. The case required tectonic keratoplasty restore globe integrity failed...
Purpose: To evaluate the outcomes of transscleral cyclophotocoagulation (CPC) in control glaucoma eyes with a Boston keratoprosthesis (KPro) type 1. Methods: This study is retrospective case series patients who have undergone at least 1 CPC treatment after KPro implantation. Eighteen 17 were included. Intraocular pressure (IOP) (assessed by digital palpation) and number classes medications recorded week, to 3 months, 4 6 year postoperatively. Optic nerve status, visual field parameters,...
This study describes the management of patients with bilobar colorectal liver metastases (CRLM).A retrospective collection data on all CRLM who were considered for staged resection (n= 85) from January 2003 to 2011 was performed. Patients underwent one hepatic have had a failed (FSR), whereas those second or third produce cure successful (SSR). Survival calculated date diagnosis metastases. Complete follow-up and dates death obtained Government Quebec population database.Median survival 46...
Abstract Purpose To report the refractive outcomes of long (≥25.00 mm) and short (≤22.00 axial length (AL) eyes undergoing immediately sequential bilateral cataract surgery (ISBCS). Methods In this retrospective cohort study, patients who underwent ISBCS were identified with ALs included. Pre- postoperative biometry, autorefraction, ocular comorbidities or complications recorded. The primary outcome was mean prediction error. Results Thirty-seven (74 eyes) 18 (36 means ± standard deviations...
This JAMA Insights Clinical Update summarizes the various types of refractive surgical procedures performed in US, including LASIK, photorefractive keratectomy, and small incision lenticule extraction.
Purpose: To report the ocular findings of a rare case mutation in nuclear-encoded mitochondrial aminoacyl-tRNA synthetase IARS2. Methods: A 33-year-old woman known for infantile cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia was referred to us multiple failed corneal grafts severe eye dryness. Results: The patient found have neurotrophic keratitis opacification. Conclusions: Patients with this very present myriad findings,...
The purpose of this non-comparative, prospective, observational study was to evaluate the post-US Food and Drug Administration approval outcomes epithelium-off, full-fluence, Dresden protocol corneal collagen crosslinking (CXL) for treatment progressive keratoconus (KCN) post-refractive ectasia at a US academic tertiary medical center. This involved 125 eyes 97 patients with KCN 13 12 which underwent CXL between November 2016 September 2019. Best spectacle-corrected visual acuity (BSCVA)...
Purpose: To describe a surgical technique of Descemet membrane endothelial keratoplasty (DMEK) using an endothelium-in pull-through with novel infusion forceps and report 6-month clinical outcomes. Methods: This is retrospective case series 33 cases Fuchs corneal dystrophy who underwent either DMEK alone (n = 5), combined phacoemulsification 27), or intraocular lens exchange 1) performed by surgeons at the beginning learning curve. Best-corrected visual acuity (BCVA), manifest refraction,...
It was the aim of this study to determine diagnostic accuracy high-risk prognostic factors and morphological characteristics retinoblastomas using digital whole slide images (WSI) generated by a scanner.Forty-seven H&E sections glass slides with features retinoblastoma were analyzed. Slides scanned as WSI reviewed. The results compared those obtained after reviewing regular microscope gold standard. McNemar's test (MT), percentage agreement (POA), sensitivity (S) specificity (Sp)...
To describe the occurrence of corneal thinning in a patient following intrastromal injection bevacizumab to treat lipid keratopathy.A 36-year-old female presented with decreased vision her right eye central posterior haze and underwent treatment regimen including artificial tears, cyclosporine 0.05% drops, prednisolone 1% oral Valacyclovir 1g no improvement. Neovascularization was noted at 18 months follow up treated injections 24 months. The feeder vessel attenuated 3- 6-months...
Purpose: This study aimed to compare outcomes and early complications using an endothelium-in pull-through Descemet membrane endothelial keratoplasty (DMEK) technique with preloaded versus surgeon-loaded donor tissue. Methods: Data from 163 eyes of 125 patients at the Wilmer Eye Institute diagnosed Fuchs corneal dystrophy who underwent DMEK or without cataract extraction tissue (n = 83) 80) were reviewed. Best-corrected visual acuity postoperative including small graft detachment (less than...
Describe three-year outcomes of spherical implantable Collamer lens (ICL) followed by excimer laser enhancement (bioptics) in eyes with high myopic astigmatism.Retrospective case series thirty-four cases that underwent bioptics at the Johns Hopkins Wilmer Eye Institute. All had a preoperative sphere -6.00 D or more cylinder least 2.00 D. Uncorrected and corrected distance visual acuity (UDVA CDVA), manifest equivalent refraction (MSE), ICL vault measurements central corneal thickness (CCT)...
The purpose of this study is to provide a comprehensive review the clinical characteristics in chronic Stevens-Johnson syndrome (SJS) patients within United Kingdom population, their causative factors, treatment profile and prognosis. This retrospective series included 91 with SJS treated at Moorfields Eye Hospital (London, Kingdom). A chart visual acuity presence findings (including lid abnormalities ocular surface findings). All medical surgical treatments were also recorded. Approximately...
To report the first case of acute angle closure due to a high-pressure Descemet membrane detachment following deep anterior lamellar keratoplasty (DALK) using "big bubble" technique. A 25-year-old man underwent DALK surgery for keratoconus technique in which an air bubble is injected stroma promote dissection underlying from stroma. Surgery was uneventful and patient discharged home good conditions. On post-operative day 1, came back with severe periocular pain. Intra-ocular pressure found...